1. Assessment of Vascular Endothelial Function With Peripheral Arterial Tonometry
- Author
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Jeffrey T. Kuvin, Eshan Patvardhan, Morgan I. Soffler, Jenny M. Ruan, Richard H. Karas, and Kevin S. Heffernan
- Subjects
medicine.medical_specialty ,Endothelium ,Manometry ,Pulsatile flow ,Arterial tonometry ,Vasodilation ,Fingers ,Internal medicine ,Humans ,Medicine ,Endothelial dysfunction ,business.industry ,Surrogate endpoint ,Arteries ,Equipment Design ,General Medicine ,Atherosclerosis ,medicine.disease ,Peripheral ,medicine.anatomical_structure ,Pulsatile Flow ,Cardiology ,Endothelium, Vascular ,Cardiology and Cardiovascular Medicine ,business ,Function (biology) - Abstract
Endothelial dysfunction is an important component in the pathogenesis of atherosclerosis. The ability to assess the endothelium in a meaningful manner has been the subject of intense investigation over decades. Since the function of endothelial cells is a gauge of vascular health, assessment of vascular function is emerging as a useful tool for predicting cardiovascular risk and as a surrogate outcome measure for cardiovascular reduction intervention studies. This review highlights techniques for assessing endothelial function, focusing on a novel method of determining peripheral vascular reactivity via arterial tonometry.
- Published
- 2010
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