1. Osteoblast differentiation and phenotype expressions on chitosan-coated Ti-6Al-4V
- Author
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Hsin-Yi Lin and Jing-Huei Chen
- Subjects
food.ingredient ,Polymers and Plastics ,Biocompatibility ,Pectin ,Alginates ,Cell Survival ,Anti-Inflammatory Agents ,macromolecular substances ,Mineralization (biology) ,Collagen Type I ,Fluorescence ,Chitosan ,chemistry.chemical_compound ,food ,Coated Materials, Biocompatible ,Glucuronic Acid ,Materials Testing ,Alloys ,Materials Chemistry ,medicine ,Animals ,Humans ,Pentoxifylline ,Composite material ,Cell Shape ,Cell Proliferation ,Titanium ,Osteoblasts ,Staining and Labeling ,Hexuronic Acids ,Organic Chemistry ,technology, industry, and agriculture ,Cell Differentiation ,Osteoblast ,Alkaline Phosphatase ,Extracellular Matrix ,Cross-Linking Reagents ,Phenotype ,medicine.anatomical_structure ,chemistry ,Pectins ,Alkaline phosphatase ,Calcium ,Swelling ,medicine.symptom ,Type I collagen ,Nuclear chemistry - Abstract
Chitosan (C), alginate-crosslinked chitosan (CA), and pectin-crosslinked chitosan (CP) were covalently bonded to Ti-6Al-4V surfaces and tested for their biocompatibility. Compared to the clinically treated Ti-6Al-4V surface (Ti64), C, CA, and CP, had higher contact angles and promoted higher cell proliferation, type I collagen deposition, and mineralization after two weeks (all p
- Published
- 2013
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