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Your search keyword '"Kamiński, Kamil"' showing total 2 results
Start Over Author "Kamiński, Kamil" Publication Year Range Last 10 years Publication Type Academic Journals Journal carbohydrate polymers
2 results on '"Kamiński, Kamil"'

2. Chitosan-based hydrogel implants enriched with calcium ions intended for peripheral nervous tissue regeneration.

Author

Nawrotek, Katarzyna, Tylman, Michał, Rudnicka, Karolina, Balcerzak, Jacek, and Kamiński, Kamil

Subjects
*HYDROGELS, *CHITOSAN, *CALCIUM ions, *NERVOUS system regeneration, *PERIPHERAL nervous system, *ELECTROPLATING, *HYDROXYAPATITE, *SOLUTION (Chemistry)
Abstract

A new method for fabrication of chitosan-based hydrogel implants intended for peripheral nervous tissue regeneration was developed. The method is based on an electrodeposition phenomenon from a solution of chitosan and organic acid. In order to increase the mechanical strength of the implant, the solution was enriched with hydroxyapatite. Hydroxyapatite served as a source of calcium ions too. The influence of the concentration of the polymer and the additive on chemical, mechanical as well as biological properties of the obtained implant was evaluated. The study showed great dependence of the initial solution composition mainly on the physicochemical properties of the resulting structure. Basic in vitro cytotoxic and pro-inflammatory assays showed biocompatibility of manufactured implants, therefore, animal experimentations may be considered. [ABSTRACT FROM AUTHOR]

Published
2016
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