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The purpose of this quasi-experimental study was to compare two teaching methods of a predialysis educational program, namely on-site and by distance. This program was offered to patients with chronic kidney disease (CKD) stage 3. The experimental group one received the on-site program, whereas the experimental group two received the teaching program by distance. This study uses a pre-test post-test design. Measures included a Sociodemographic Information Form, the Degree of Knowledge Integration (Aucoin-Gallant, 1998), and the Knowledge Satisfaction Scale (Aucoin, 1998). In this study, both groups are homogenous from a sociodemographic perspective and have similar creatinine clearance values. Findings demonstrate an increase with knowledge integration and satisfaction with knowledge that is statistically significant for both groups of subjects. Participants in group two learned as much as participants in group one. This study highlights that knowledge integration leads to satisfaction in both groups of subjects. The results demonstrate that predialysis teaching delivered on-site or by distance promotes knowledge integration for patients with CKD stage 3.