1. Ductal carcinoma in situ (DCIS) of the breast: is there an optimal management?
- Author
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Kanavou, Theodora, Lazoura, Olga, Tsilikas, Konstantinos, Karanikas, Christos, and Vassiou, Katerina
- Subjects
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CARCINOMA in situ , *DUCTAL carcinoma , *AXILLARY lymph node dissection , *MAGNETIC resonance imaging , *LUMPECTOMY , *RADIOTHERAPY - Abstract
The last decades, due to the systematic mammographic screening control, the incidence of DCIS has impressively increased and it consists almost 20% of breast carcinomas. A number of pathologic features have been identified which are useful for classification of ductal in situ carcinoma (DCIS) and better understanding of its pathogenesis and biological behavior. Recent advances in the diagnosis of DCIS include magnetic resonance imaging as an adjunct to mammography, which remains the gold standard for DCIS detection. The optimal management of DCIS remains an issue of controversy. Mastectomy that was practiced for long has been replaced in most cases by breast conserving-surgery with or without radiotherapy; radiotherapy significantly reduces local recurrence. Axillary lymph node dissection is generally not recommended. Tamoxifen appears to reduce the risk of local recurrence and should be considered in the management of selected patients with DCIS. [ABSTRACT FROM AUTHOR]
- Published
- 2009