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Your search keyword '"Thomalla, J"' showing total 11 results
Start Over Author "Thomalla, J" Journal cancer research
11 results on '"Thomalla, J"'

1. Abstract PD2-07: mRNA signatures predict response to durvalumab therapy in triple negative breast cancer (TNBC)– Results of the translational biomarker programme of the neoadjuvant double-blind placebo controlled GeparNuevo trial

Author

Loibl, S, primary, Sinn, BV, additional, Karn, T, additional, Untch, M, additional, Treue, D, additional, Sinn, H-P, additional, Weber, KE, additional, Hanusch, CA, additional, Fasching, PA, additional, Huober, J, additional, Zahm, D-M, additional, Jackisch, C, additional, Thomalla, J, additional, Blohmer, J-U, additional, Marmé, F, additional, Klauschen, F, additional, Rhiem, K, additional, Felder, B, additional, von Minckwitz, G, additional, Burchardi, N, additional, Schneeweiss, A, additional, and Denkert, C, additional

Published
2019
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2. Abstract PD5-05: Pre-therapeutic PD-L1 expression and dynamics of Ki-67 and gene expression during neoadjuvant immune-checkpoint blockade and chemotherapy to predict response within the GeparNuevo trial

Author

Sinn, BV, primary, Loibl, S, additional, Karn, T, additional, Untch, M, additional, Kunze, CA, additional, Weber, KE, additional, Treue, D, additional, Wagner, K, additional, Hanusch, CA, additional, Klauschen, F, additional, Fasching, PA, additional, Huober, J, additional, Zahm, D-M, additional, Jackisch, C, additional, Thomalla, J, additional, Blohmer, J-U, additional, van Mackelenbergh, M, additional, Rhiem, K, additional, Felder, B, additional, von Minckwitz, G, additional, Burchardi, N, additional, Schneeweiss, A, additional, and Denkert, C, additional

Published
2019
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3. Abstract P1-16-06: Improved survival of patients with metastatic breast cancer in routine care is restricted to tumors with positive hormone receptor and/or Her2-expression. Survival analysis of 1,321 patients treated between 1995 and 2017 in oncology group practices

Author

Weide, R, primary, Rendenbach, B, additional, Laubenstein, H-P, additional, Braun, U, additional, Hünermund, K, additional, Burkhard, O, additional, Ehscheidt, P, additional, Feiten, S, additional, Chakupurakal, G, additional, Friesenhahn, V, additional, Kleboth, K, additional, Köppler, H, additional, Lutschkin, J, additional, Thomalla, J, additional, van Roye, C, additional, and Heymanns, J, additional

Published
2019
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4. Abstract P6-15-01: Withdrawn

Author

Loibl, S, primary, Untch, M, additional, Denkert, C, additional, Huober, J, additional, Blohmer, JU, additional, Grischke, E-M, additional, Furlanetto, J, additional, Tesch, H, additional, Hanusch, C, additional, Rezai, M, additional, Jackisch, C, additional, Schmitt, WD, additional, von Minckwitz, G, additional, Thomalla, J, additional, Kümmel, S, additional, Rautenberg, B, additional, Fasching, PA, additional, Rhiem, K, additional, Burchardi, N, additional, and Schneeweiss, A, additional

Published
2018
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5. Abstract P5-16-01: A randomised phase III trial comparing two dose-dense, dose-intensified approaches (ETC and PM(Cb)) for neoadjuvant treatment of patients with high-risk early breast cancer (GeparOcto)

Author

Schneeweiss, A, primary, Möbus, V, additional, Tesch, H, additional, Hanusch, C, additional, Denkert, C, additional, Lübbe, K, additional, Huober, J, additional, Klare, P, additional, Kümmel, S, additional, Untch, M, additional, Kast, K, additional, Jackisch, C, additional, Ingold-Heppner, B, additional, Thomalla, J, additional, Blohmer, J-U, additional, Rezai, M, additional, Nekljudova, V, additional, von Minckwitz, G, additional, and Loibl, S, additional

Published
2017
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11. Patient Reported Outcomes after Breast Cancer Surgery and Adjuvant Therapy from a German Breast Cancer Centre.

Author

Feiten, S., Dünnebacke, J., Heymanns, J., Köppler, H., Thomalla, J., van Roye, C., Wey, D., and Weide, R.

Subjects
*BREAST cancer research, *BREAST cancer patients, *ADJUVANT treatment of cancer, *HORMONE therapy, *TAMOXIFEN
Abstract

Objectives: Evaluation of the subjectively experienced physical, psychological, social and job-related consequences of breast cancer. Methods: Standardized paper pencil interview of patients with the initial diagnosis of breast cancer who had their primary surgery between 01/2006 and 12/2010 at an accredited breast cancer centre followed by systemic adjuvant treatment. The data collection was conducted with the help of a self-developed scanner-readable questionnaire which had been evaluated in a pretest. Results: 1260 patients were contacted, 871 completed questionnaires (return rate 72%) were analyzed. Median age of the patients (99.5% women) at the time of the interview was 65 years (30-91). 6% relapsed during the observation period. 91% were "satisfied" or "very satisfied" with the surgical result. 67% indicated a complete freedom of pain. 23% received lymphatic drainage at the time of the questioning (11/2011), 33% complained about limitations of arm and/or shoulder function. 76% received anti-hormonal therapy, 13% stopped the anti-hormonal medication prematurely. Patients received a mean of 1.3 different anti-hormonal therapies, 54% took Tamoxifen. Psychological distress, cognitive limitations and physical consequences were rated on a scale from 1--"not at all" to 4--"very much". The highest average values were found for the items sleep disturbances (2.3) and exhaustion (2.3), the lowest for depression (1.7) and word-finding difficulties (1.8). After therapy only 39% described a complete recovery of their physical capacity, 62% regained their previous mental capacity. 44% were in employment before their disease. 67% returned to their workplace but only 65% of them with their previous number of hours. 15% indicated disadvantages in their workplace due to the breast cancer disease. For 75% their partnership did not change, 12% experienced a deterioration, 13% an improvement. Before the illness 9% consulted a psychiatrist/psychotherapist, after the illness 18%. Before the diagnosis of breast cancer 13% received antipsychotic drugs, after the disease 25%. Conclusions: Breast cancer diagnosis and therapy leads to long lasting impairment of physical, psychological, social and job-related functioning in a significant number of patients. [ABSTRACT FROM AUTHOR]

Published
2012
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