29 results on '"Pao, William"'
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2. EPHA2 Blockade Overcomes Acquired Resistance to EGFR Kinase Inhibitors in Lung Cancer
3. Abstract 752: Elucidating the mechanisms of acquired resistance in lung adenocarcinomas
4. Acquired Resistance to the Mutant-Selective EGFR Inhibitor AZD9291 Is Associated with Increased Dependence on RAS Signaling in Preclinical Models
5. Abstract PR16: Spatio-temporal heterogeneity in the tumor microenvironment influences the evolutionary dynamics of drug resistance
6. Abstract 956: Elucidating the mechanisms of acquired resistance in lung adenocarcinomas
7. Abstract 1722: Investigating resistance to AZD9291
8. Abstract 1106: Mechanism for activation of mutated EGF receptors in lung cancer.
9. Abstract 2438: Mechanisms of sensitivity and resistance to Sym004, a novel anti-EGFR antibody mixture, in EGFR mutant lung cancer.
10. Abstract 933: Modeling acquired resistance to EGFR-directed therapies in mouse models of lung cancer.
11. Abstract 1897: RAS signaling pathway gene mutations and acquired resistance to EGFR tyrosine-kinase inhibitors in EGFR mutant lung cancer
12. Abstract 5102: Identifying targets for melanoma therapy: Biological and clinical implications of BRAF L597 mutants
13. Abstract 5479: Somatic driver mutations among never smoking female lung cancer cases in China identify unique mutation pattern that may be associated with household coal burning
14. Insights into ALK-Driven Cancers Revealed through Development of Novel ALK Tyrosine Kinase Inhibitors
15. Abstract LB-236: Identifying novel kinase fusions via targeted DNA capture and next-generation sequencing
16. Abstract 2417: A new mouse model for epithelial ear neoplasms based upon expression of mutant EGFRL858R/T790M
17. Abstract 731: Nuclear factor-κB activation and cetuximab-resistance in HNSCC cell lines
18. Abstract 4689: Inhibition of IL-6/Jak/Stat3 signaling: a novel and potent targeting therapy for lung cancer
19. Abstract 2836: Rapamycin prolongs overall survival and progression-free survival in a mouse model of lung cancer in never smokers resistant to erlotinib
20. Abstract 4977: Targeted next-generation sequencing of DNA regions proximal to a conserved GXGXXG signaling motif enables discovery of a novel C6orf204-PDGFRβ fusion in a patient with T-ALL and eosinophilia
21. Abstract 231: Upregulation of HER3 (ErbB3) levels and function counteracts the antitumor effect of HER2 and PI3K inhibitors
22. Abstract 1774: Selection for the EGFR T790M gatekeeper resistance mutation may vary among different small molecule EGFR TKIs
23. Abstract 1784: Erlotinib at a dose of 25 mg daily for non-small cell lung cancers with EGFR mutations
24. Abstract 624: Synergistic effects of combining the Akt inhibitor triciribine with erlotinib in EGFR TKI-resistant NSCLC
25. Abstract 1788: Preclinical development of a selective, potent small molecule ALK inhibitor
26. PTEN Loss Contributes to Erlotinib Resistance in EGFR-Mutant Lung Cancer by Activation of Akt and EGFR
27. Genetic Predictors of MEK Dependence in Non–Small Cell Lung Cancer
28. Novel MEK1 Mutation Identified by Mutational Analysis of Epidermal Growth Factor Receptor Signaling Pathway Genes in Lung Adenocarcinoma
29. Serum levels of surfactant protein D are increased in mice with lung tumors.
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