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Your search keyword '"Saskia J Santegoets"' showing total 1 results
Start Over Author "Saskia J Santegoets" Journal cancer immunology, immunotherapy : cii
1 results on '"Saskia J Santegoets"'

1. The common HLA class I-restricted tumor-infiltrating T cell response in HPV16-induced cancer

Author

Saskia J, Santegoets, Marij J P, Welters, Deborah S, Schrikkema, Manon R, Freriks, Hanna, Kok, Bianca, Weissbrich, Anouk, van den Branden, Carsten, Linnemann, Ton N, Schumacher, Sabina, Adhikary, Gavin, Bendle, and Sjoerd H, van der Burg

Abstract

Immunotherapies targeting truly tumor-specific targets focus on the expansion and activation of T cells against neoantigens or oncogenic viruses. One target is the human papilloma virus type 16 (HPV16), responsible for several anogenital cancers and oropharyngeal carcinomas. Spontaneous and vaccine-induced HPV-specific T cells have been associated with better clinical outcome. However, the epitopes and restriction elements to which these T cells respond remained elusive. To identify CD8

Published
2022

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