1. From anatomical to biological target volumes: the role of PET in radiation treatment planning.
- Author
-
Schinagl DA, Kaanders JH, and Oyen WJ
- Subjects
- Cell Hypoxia, Clinical Trials as Topic, Fluorodeoxyglucose F18 pharmacokinetics, Humans, Image Interpretation, Computer-Assisted, Magnetic Resonance Imaging, Misonidazole analogs & derivatives, Misonidazole pharmacokinetics, Neoplasms metabolism, Neoplasms pathology, Neoplasms radiotherapy, Observer Variation, Radiation Tolerance, Radiopharmaceuticals pharmacokinetics, Reproducibility of Results, Sensitivity and Specificity, Tomography, X-Ray Computed, Tumor Burden, Neoplasms diagnostic imaging, Patient Care Planning, Positron-Emission Tomography methods, Radiotherapy
- Abstract
Progress in radiation oncology requires a re-evaluation of the methods of target volume delineation beyond anatomical localization. New molecular imaging techniques for tumour visualisation such as positron emission tomography (PET) provide insight into tumour characteristics and can be complementary to the anatomical data of computed tomography or magnetic resonance imaging. In this review, three issues are discussed: First, can PET identify a tumour more accurately? Second, can biological tumour characteristics be visualised? Third, can intratumoural heterogeneity of these characteristics be identified?, ((c) International Cancer Imaging Society.)
- Published
- 2006
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