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Start Over Author "Leroux D" Journal cancer genetics and cytogenetics
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6. Bloom's syndrome: in vitro correction of the sister chromatid exchange rate by normal cells.

Author

Leroux D, Chmara D, and Jalbert P

Subjects
Adult, Cells, Cultured, Female, Fibroblasts physiology, Humans, Skin physiopathology, Bloom Syndrome genetics, Crossing Over, Genetic, Sister Chromatid Exchange
Abstract

A significant decrease of sister chromatid exchange (SCE) frequencies was observed in Bloom's syndrome(BS) fibroblasts by cocultivation with normal fibroblasts at 5:1, 1:1, 1:5 ratios, and by culture in medium previously used to support normal fibroblasts. On the other hand, the SCE rate of normal fibroblasts was not modified. These results are compared with those from other studies and discussed.

Published
1984
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