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1. Toward a better understanding of T cells in cancer

Author

David Y. Oh, Lawrence Fong, Evan W. Newell, Mary Jo Turk, Hongbo Chi, Howard Y. Chang, Ansuman T. Satpathy, Benjamin Fairfax, Bruno Silva-Santos, and Olivier Lantz

Subjects
Cancer Research, Oncology, Neoplasms, T-Lymphocytes, Humans, Immunotherapy
Abstract

T cells mediate anti-tumor immune responses and are the key target of immune checkpoint therapy, but they can also promote immune tolerance. A clear understanding of the specific contributions and biology of different T cell subsets is required to fully harness the curative potential of immunotherapies. Experts discuss the state of the field and key challenges for moving forward.

Published
2021

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