1. Have incidence rates of liver cancer peaked in the United States?
- Author
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Petrick, Jessica L, Florio, Andrea A, Loomba, Rohit, and McGlynn, Katherine A
- Subjects
Humans ,Hepatitis C ,Carcinoma ,Hepatocellular ,Cholangiocarcinoma ,Bile Duct Neoplasms ,Liver Neoplasms ,Registries ,SEER Program ,Adult ,Aged ,Aged ,80 and over ,Middle Aged ,United States ,Female ,Male ,Surveillance ,Epidemiology ,and End Results ,age-standardized incidence rates ,hepatocellular carcinoma ,intrahepatic cholangiocarcinoma ,Digestive Diseases ,Hepatitis ,Cancer ,Rare Diseases ,Infectious Diseases ,Liver Cancer ,Liver Disease ,Chronic Liver Disease and Cirrhosis ,Good Health and Well Being ,Surveillance ,Epidemiology ,and End Results ,Oncology and Carcinogenesis ,Public Health and Health Services ,Oncology & Carcinogenesis - Abstract
BackgroundLiver cancer incidence has increased for several decades in the United States. Recently, reports have suggested that rates of hepatocellular carcinoma (HCC), the dominant form of liver cancer, had declined in certain groups. However, to the authors' knowledge, the most recent histology-specific liver cancer rates have not been reported to date.MethodsThe authors examined the incidence of HCC and intrahepatic cholangiocarcinoma (ICC) from 1992 through 2016 using data from the Surveillance, Epidemiology, and End Results registries. Age-standardized incidence rates were calculated by histology, sex, race and/or ethnicity, and age. Trends were analyzed using the National Cancer Institute's Joinpoint Regression Program to estimate the annual percent change.ResultsBetween 2011 and 2016, HCC rates significantly declined (annual percent change, -1.9%), with more prominent declines noted among males, Asian/Pacific Islanders, and individuals aged
- Published
- 2020