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2 results on '"Lambroza A"'

1. Treatment-related esophageal stricture in pediatric patients with cancer

Author

Ellenhorn, Joshua D.I., Lambroza, Arnon, Lindsley, Karen L., and LaQuaglia, Michael P.

Subjects
Cancer in children -- Complications, Chemotherapy -- Complications, Esophagus -- Motility, Antineoplastic agents -- Adverse and side effects, Health
Abstract

Background. Intensive antineoplastic regimens have enhanced long-term survival in pediatric patients with cancer, but can result in long-term complications. Esophageal stricture formation is one such complication. Methods. We reviewed the experience with benign esophageal stricture in pediatric patients with cancer over the past 15 years in a major cancer center. Clinical course, along with endoscopic, radiologic, and manometric esophageal studies, was reviewed. Results. Esophageal strictures formed in five pediatric patients who were treated with radiation and/or chemotherapy. Stricture formation was associated with abnormal esophageal motility in four out of the five patients. Repeated esophageal dilation was performed from 3-50 times and resulted in stricture resolution in only 2 of the 5 patients. Conclusions. Esophageal stricture formation in this population is rare, but is associated with long-term morbidity.

Published
1993

2. Treatment-related esophageal stricture in pediatric patients with cancer

Author

Karen L. Lindsley, Joshua D. I. Ellenhorn, Michael P. LaQuaglia, and Arnon Lambroza

Subjects
Cancer Research, medicine.medical_specialty, education.field_of_study, business.industry, Esophageal disease, medicine.medical_treatment, Population, Cancer, medicine.disease, Surgery, Radiation therapy, Stenosis, medicine.anatomical_structure, Oncology, Esophageal motility disorder, Esophageal stricture, medicine, Esophagus, business, education
Abstract

Background. Intensive antineoplastic regimens have enhanced long-term survival in pediatric patients with cancer, but can result in long-term complications. Esophageal stricture formation is one such complication. Methods. We reviewed the experience with benign esophageal stricture in pediatric patients with cancer over the past 15 years in a major cancer center. Clinical course, along with endoscopic, radiologic, and manometric esophageal studies, was reviewed. Results. Esophageal strictures formed in five pediatric patients who were treated with radiation and/or chemotherapy. Stricture formation was associated with abnormal esophageal motility in four out of the five patients. Repeated esophageal dilation was performed from 3–50 times and resulted in stricture resolution in only 2 of the 5 patients. Conclusions. Esophageal stricture formation in this population is rare, but is associated with long-term morbidity.

Published
1993

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