1. Do contemporary imaging and biopsy techniques reliably identify unilateral prostate cancer? Implications for hemiablation patient selection.
- Author
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Johnson, David, Yang, Jason, Kwan, Lorna, Barsa, Danielle, Mirak, Sohrab, Pooli, Aydin, Sadun, Taylor, Jayadevan, Rajiv, Zhou, Steve, Priester, Alan, Natarajan, Shyam, Bajgiran, Amirhossein, Shakeri, Sepideh, Sisk, Anthony, Felker, Ely, Raman, Steven, Marks, Leonard, and Reiter, Robert
- Subjects
focal therapy ,hemiablation ,magnetic resonance imaging ,patient selection ,prostatectomy ,prostatic neoplasms ,unilateral ,Humans ,Image-Guided Biopsy ,Male ,Middle Aged ,Patient Selection ,Prostatic Neoplasms ,Retrospective Studies ,Ultrasound ,High-Intensity Focused ,Transrectal - Abstract
BACKGROUND: Hemiablation is a less morbid treatment alternative for appropriately selected patients with unilateral prostate cancer (PCa). However, to the authors knowledge, traditional diagnostic techniques inadequately identify appropriate candidates. In the current study, the authors quantified the accuracy for identifying hemiablation candidates using contemporary diagnostic techniques, including multiparametric magnetic resonance imaging (mpMRI) and MRI-fusion with complete systematic template biopsy. METHODS: A retrospective analysis of patients undergoing MRI and MRI-fusion prostate biopsy, including full systematic template biopsy, prior to radical prostatectomy in a single tertiary academic institution between June 2010 and February 2018 was performed. Hemiablation candidates had unilateral intermediate-risk PCa (Gleason score [GS] of 3+4 or 4+3, clinical T classification ≤T2, and prostate-specific antigen level
- Published
- 2019