1. Correlation between Total Solar Irradiance and Glycated Hemoglobin 2 to 3 Months Later in Patients with Diabetes: A Big-Data Analysis
- Author
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Kazuhiko Kotani, Yukiko Maruguchi, Shigesumi Kinchiku, Anna Aikou, Shouko Kajiya, and Hitoshi Uenomachi
- Subjects
Male ,medicine.medical_specialty ,Correlation coefficient ,Endocrinology, Diabetes and Metabolism ,Statistics as Topic ,Population ,030209 endocrinology & metabolism ,Type 2 diabetes ,Solar irradiance ,Medical Records ,03 medical and health sciences ,chemistry.chemical_compound ,0302 clinical medicine ,Endocrinology ,Diabetes mellitus ,Internal medicine ,Internal Medicine ,medicine ,Humans ,030212 general & internal medicine ,education ,Glycemic ,Glycated Hemoglobin ,education.field_of_study ,Type 1 diabetes ,business.industry ,General Medicine ,Middle Aged ,Prognosis ,medicine.disease ,Surgery ,Diabetes Mellitus, Type 1 ,Diabetes Mellitus, Type 2 ,chemistry ,Sunlight ,Female ,Glycated hemoglobin ,business ,Biomarkers ,Follow-Up Studies - Abstract
Objectives Much attention has been paid recently to a relationship between glucose metabolism and weather. This study investigated the temporal correlation between total solar irradiance (TSI) and glycated hemoglobin (A1C) values in patients with diabetes. Methods In 1531 patients with diabetes who received follow-up care between 2009 and 2013 (type 1 diabetes, 123 patients; type 2 diabetes, 1408 patients; male 53.6%; mean age, 61.2 years), A1C levels were measured a total of 58,830 times. The correlation between mean monthly TSI and mean A1C values from 1 to 4 months later was then examined. Results The mean values for TSI and A1C throughout the entire study period were 13.7 MJ/m 2 and 7.7%, respectively. The correlation coefficient between TSI and mean monthly A1C values at 1 to 4 months was −0.516, −0.734, −0.726 and −0.475, respectively (all p Conclusions There was a highly negative correlation between TSI and mean A1C values 2 to 3 months later in this population; thus, this fact may need to be considered when using A1C levels as a glycemic control index in patients with diabetes. Further studies are warranted.
- Published
- 2016
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