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Your search keyword '"Verardo, Giancarlo"' showing total 6 results
Start Over Author "Verardo, Giancarlo" Journal canadian journal of chemistry
6 results on '"Verardo, Giancarlo"'

1. Exploring the reaction of formaldehyde with α-N-protected amino acid hydrazides

Author

Verardo, Giancarlo, Geatti, Paola, Mancuso, Marta, and Strazzolini, Paolo

Subjects
Condensation -- Research, Amino acids -- Properties -- Research, Formaldehyde -- Properties -- Research, Chemistry, Research, Properties
Abstract

Abstract: The reaction of formaldehyde with enantiomerically pure α-N-protected amino acid hydrazides is described. The system has been investigated in different solvents, including both aqueous formaldehyde and paraformaldehyde, with the [...]

Published
2008

2. Sodium borohydride: a versatile reagent in the reductive N-monoalkylation of [alpha]-amino acids and [alpha]-amino methyl esters

Author

Verardo, Giancarlo, Geatti, Paola, Pol, Elena, and Giumanini, Angelo G.

Subjects
Chemical tests and reagents, Amino acids, Oxidation-reduction reaction -- Analysis, Nitrogen, Boron, Sodium compounds, Esters, Chemical research -- Analysis
Abstract

[alpha]-Amino acids and [alpha]-amino methyl esters are easily converted to their N-monoalkyl derivatives by a reductive condensation reaction using several carbonyl compounds in the presence of sodium borohydride. This reducing agent has shown a wide versatility with minor but essential procedural variations. The reaction allows the [alpha]-monodeuterium labeling of the new N-substituent by use of sodium borodeuteride. Key words: [alpha]-amino acid, [alpha]-amino methyl esters, sodium borohydride, reductive N-monoalkylation, carbonyl compounds.

Published
2002

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