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Start Over Author "I P Ganshina" Journal bulletin of experimental biology and medicine
1 results on '"I P Ganshina"'

1. Variations in the number of regulatory T cells (CD4+CD25+) in patients with breast cancer during herceptin therapy

Author

Slavina Eg, I. P. Ganshina, A. I. Chertkova, M. R. Lichinitser, and T. N. Zabotina

Subjects
Oncology, Adult, medicine.medical_specialty, T-Lymphocytes, Population, Antineoplastic Agents, Breast Neoplasms, Antibodies, Monoclonal, Humanized, General Biochemistry, Genetics and Molecular Biology, Interleukin 21, Breast cancer, Trastuzumab, Internal medicine, Medicine, Humans, In patient, IL-2 receptor, skin and connective tissue diseases, education, education.field_of_study, biology, business.industry, Interleukin-2 Receptor alpha Subunit, Antibodies, Monoclonal, General Medicine, Middle Aged, medicine.disease, Monoclonal, CD4 Antigens, biology.protein, Female, Antibody, business, medicine.drug
Abstract

We studied the effect of Herceptin therapy on the population composition of lymphocytes and percentage of CD4+CD25+ cells (regulatory T cells) in breast cancer patients. Herceptin treatment decreased the number of "professional" T suppressors (CD4+CD25+ cells and regulatory T cells) in the peripheral blood.

Published
2006

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