1. Cholestyramine in treatment of postvagotomy diarrhoea--double-blind controlled trial
- Author
-
R. I. Russell and J G Allan
- Subjects
Diarrhea ,Male ,medicine.medical_specialty ,Postvagotomy diarrhoea ,Cholestyramine Resin ,Vagotomy ,Placebo ,Gastroenterology ,law.invention ,Double blind ,Randomized controlled trial ,law ,Internal medicine ,Medicine ,Humans ,Statistical analysis ,General Environmental Science ,Clinical Trials as Topic ,Cholestyramine ,business.industry ,General Engineering ,General Medicine ,Endocrinology ,General Earth and Planetary Sciences ,Drug Evaluation ,Female ,business ,medicine.drug ,Research Article - Abstract
A double-blind controlled trial was performed to assess the effectiveness of cholestyramine in treating severe continuous postvagotomy diarrhoea. Each patient and a clinician assessed the results, and those treated with cholestyramine showed a considerable improvement over those given placebo. There were no significant side effects or changes in laboratory values in the cholestyramine group. Although the numbers were too small for statistical analysis, these results suggest that cholestyramine may be of value in the management of some patients with severe continuous postvagotomy diarrhoea who are unresponsive to other forms of treatment.
- Published
- 1977