Search

This article discusses strategies to strengthen elective surgery systems during the SARS-CoV-2 pandemic. It explores adaptations such as the hub-and-spoke model and weekend surgeries to support the continuation of elective surgery. The study identifies six strategies to expand surgical capacity, emphasizing the need for tailored approaches and planning. The text also discusses the dependence on contract conditions and the importance of workforce and financing. The article concludes by suggesting areas for future research and the need for diverse perspectives in decision-making. Additionally, a document is provided that covers various studies and articles on COVID-secure sites for elective surgeries, discussing feasibility, outcomes, and experiences in different surgical specialties. [Extracted from the article]

This document discusses the importance of reliable electricity in healthcare facilities, particularly operating theatres, in the Global South. The lack of access to clean and secure energy can have significant impacts on vulnerable populations, such as women and children. The document presents data from a global assessment of surgical preparedness, showing that unreliable electricity supply is more common in low- and middle-income countries compared to high-income countries. The authors emphasize the need to prioritize clean energy for operating theatres in the Global South as a step towards decarbonizing healthcare and improving overall healthcare capacity. [Extracted from the article]

Aims: The cell adhesion protein, P-cadherin is known to be abnormally expressed in ulcerative (UC) and Crohn's (Cr) colitis. Our aim was to determine whether placental (P) cadherin and β-catenin was aberrantly expressed in UC dysplastic and neoplastic lesions (UCCRC). Methods: Archival paraffin-embedded sections consisted of the following: 18 UCCRC (six well; eight moderately and four poorly differentiated adenocarcinomas) and nine dysplastic lesions. Immunohistochemistry was carried out using P-cadherin and β-catenin. The distribution of P-cadherin and β-catenin was classified according to their distribution in the nuclei, cell membrane or cytoplasm. Results: P-cadherin and β-catenin were expressed in the cytoplasm and basal cell membrane of all the dysplastic, well and moderately differentiated carcinomas. There was no expression in the poorly differentiated carcinomas. There was nuclear expression of β-catenin in two well and two moderately differentiated carcinomas. Conclusions: Aberrant P-cadherin is associated with UCCRC and dysplasia, and is seen in the absence of β-catenin nuclear translocation. Interestingly, both these features are absent in poorly differentiated tumours. Although the numbers are small, this might indicate a specific role for P-cadherin in early UC-related neoplasia. [ABSTRACT FROM AUTHOR]