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The Annual Scientific Meeting of the Association of Surgeons of Great Britain and Ireland takes place this year at Bournemouth International Centre, Bournemouth, UK (14th - 16th May 2008), under the presidency of Professor Brian J Rowlands. To view all abstracts of oral presentations from this meeting, please click the pdf link on this page. Copyright © 2008 British Journal of Surgery Society Ltd. Published by John Wiley & Sons, Ltd. [ABSTRACT FROM AUTHOR]

The Annual Scientific Meeting of the Association of Surgeons of Great Britain and Ireland takes place this year at Bournemouth International Centre, Bournemouth, UK (14th - 16th May 2008), under the presidency of Professor Brian J Rowlands. To view all abstracts of poster presentations from this meeting, please click the pdf link on this page. Copyright © 2008 British Journal of Surgery Society Ltd. Published by John Wiley & Sons, Ltd. [ABSTRACT FROM AUTHOR]

The Annual Scientific Meeting of the Association of Surgeons of Great Britain and Ireland takes place this year at Manchester Central (18th - 20th April 2007), under the presidency of Professor Brian J Rowlands. To view all abstracts of oral presentations from this meeting, please click the pdf link on this page. [ABSTRACT FROM AUTHOR]

The Annual Scientific Meeting of the Association of Surgeons of Great Britain and Ireland takes place this year at Manchester Central (18th - 20th April 2007), under the presidency of Professor Brian J Rowlands. To view all abstracts of poster presentations from this meeting, please click the pdf link on this page. [ABSTRACT FROM AUTHOR]

The Vascular Society AGM was held at the Bournemouth International Centre, Bournemouth, UK 23rd - 25th November 2005. To view all abstracts from this meeting, please click the pdf link on this page. [ABSTRACT FROM AUTHOR]

The Annual Meeting of the Society of Academic and Research Surgery was held at the University of Nottingham Medical School, Nottingham, on Wednesday 4th and Thursday 5th January 2012 under the Presidency of Professor J Andrew Bradley. The Patey Prize was awarded to Miss M Mallik from the University Department of Surgery, Addenbrooke's Hospital, Cambridge Biomedical Research Centre, Cambridge, for her presentation entitled REGULATORY B CELLS INDUCE LONG-TERM ALLOGRAFT SURVIVAL IN A MOUSE MODEL OF CHRONIC REJECTION. The Norman Williams Prize for the best clinical paper was awarded to Miss S A Hosgood from University of Leicester, Department of 31s, Transplant Group for her presentation entitled PLACEBO CONTROLLED DOUBLE BLIND RANDOMISED CLINICAL TRIAL OF TRANSVERSUS ABDOMINIS PLANE BLOCK IN LIVE DONOR NEPHRECTOMY. The Kevin Burnand Prize for the best experimental/basic science paper was awarded to Mr S Buczacki from Cancer Research UK, Cambridge Research Institute, Cambridge, for his presentation entitled CHARACTERISATION OF QUIESCENT INTESTINAL STEM AND CANCER STEM CELLS. The President's Poster Prize was awarded to Mr S Awad from Division of Gastrointestinal Surgery, Nottingham University Hospitals, Queen's Medical Centre, Nottingham for his poster presentation entitled PREOPERATIVE ORAL CARBOHYDRATE LOADING IN ELECTIVE SURGERY: A META-ANALYSIS. Copyright © 2012 British Journal of Surgery Society Ltd. Published by John Wiley & Sons, Ltd. [ABSTRACT FROM AUTHOR]

The Annual Meeting of the Society of Academic and Research Surgery was held at the Botanical Gardens, Birmingham on 9th to 11th January 2008. The Patey Prize was awarded to Ms Dearbhaile Collins (Department of Surgical Research, RCSI & Beaumont Hospital, Dublin, Ireland) for a paper entitled 'Proteomic analysis of the proto-oncogene C-MYC unfolds a mechanism of receptor cross-talk that drives tumour recurrence'. All Patey Prize abstracts are reproduced in the British Journal of Surgery ( Br J Surg 2008; 95: 934-938). To view all other abstracts from this meeting, please click the pdf link on this page. Copyright © 2008 British Journal of Surgery Society Ltd. Published by John Wiley & Sons, Ltd. [ABSTRACT FROM AUTHOR]

The 2007 Annual Meeting of the Society of Academic and Research Surgery was held at Robinson College, Cambridge, UK 10-12th January 2007. The Patey Prize was won by B Modarai et al. (King's College and Imperial College, London, UK) for a paper entitled 'Adenvirus-mediated VEGF gene therapy enhances venous thrombus recanalisation and resolution'. All Patey Prize abstracts are reproduced in the British Journal of Surgery ( Br J Surg 2007; 94: 1048-1052). To view all other abstracts from this meeting, please click the pdf link on this page. [ABSTRACT FROM AUTHOR]

Background: This paper reports a 7-year experience of cryoablation for colorectal and non-colorectal liver metastases. Methods: A retrospective review was undertaken of patients treated in two adjacent UK centres in the north-west of England. Results: Over a 7-year period (1993-2000), 57 patients underwent cryotherapy for malignant hepatic tumours (41 colorectal, 16 non-colorectal). In the patients with colorectal metastases, preoperative carcinoembryonic antigen (CEA) levels fell significantly, from a mean of 444.1 to 6.22 μg/1 (P = 0.002). One patient died, two developed cryoshock and six had cardiorespiratory complications. All patients with colorectal metastases subsequently received 5-fluorouracil-based chemotherapy. The remaining 16 patients with non-colorectal tumours (seven neuroendocrine metastases, five hepatocellular carcinomas, three sarcomas, one cholangiocarcinoma) all received cryotherapy alone, with no major complications. The median survival for patients with non-colorectal metastases was 37 months, compared with 22 months for those with colorectal metastases (P = 0.005). Conclusion: Hepatic cryotherapy is effective and safe, as demonstrated by the significant reduction in postoperative CEA concentration and the low risk of complications. However, this initial short-term success was not reflected in 5-year survival rates. Cryotherapy for non-colorectal metastases had a greater long-term survival benefit and is a useful means of controlling symptoms. [ABSTRACT FROM AUTHOR]

Background: Hereditary non-polyposis colorectal cancer (HNPCC) is an inherited genetic condition associated with microsatellite instability; it accounts for around 5 per cent of all cases of colorectal cancer. This review examines recent data on management strategies for this condition. Methods: A Medline-based literature search was performed using the keywords 'HNPCC' and 'microsatellite instability'. Additional original papers were obtained from citations in articles identified by the initial search. Results and conclusion: The Amsterdam criteria identify patients in whom the presence of an inherited mutation should be investigated. Those with a mutation should be offered counselling and screening. The role of prophylactic surgery has been superseded by regular colonoscopy, which dramatically reduces the risk of colorectal cancer. Screening for extracolonic malignancy is also advocated, but the benefits are uncertain. Chemoprevention may be of value in lowering the incidence of bowel cancer in affected patients, but further studies are required. [ABSTRACT FROM AUTHOR]

Summary Background Some patients with irritable bowel syndrome (IBS) may undergo unnecessary cholecystectomy. This paper describes the prevalence of cholecystectomy and IBS in a sample of British adults in Teesside. Associations between the two conditions and their relationship to consultation behaviour and socioeconomic status are described. The results are compared with those from Bristol in an attempt to determine the influence of service-related factors on the prevalence of cholecystectomy. Methods A postal questionnaire was sent to 4432 adults aged 20–69 years registered with six general practices. The Standard Occupational Classification was used as a proxy for socioeconomic status. Results In Teesside cholecystectomy was reported by 4·1 per cent of women and 1·3 per cent of men. Some 22·9 per cent of the women had IBS, and 10·5 per cent of men. Cholecystectomy was more common in patients with IBS (odds ratio 1·9 (95 per cent confidence interval 1·2–3·2); P < 0·01). The prevalence of cholecystectomy, of IBS and of consultation for symptoms of IBS was not influenced by socioeconomic status. Conclusion Symptoms of IBS may cause diagnostic confusion and unproductive surgery. Cholecystectomy may cause IBS-like symptoms, a single underlying disorder may produce symptoms in both gastrointestinal and biliary tracts, or the associations might be due to a combination of these factors. Presented as a poster to the World Congress of Gastroenterology, Vienna, Austria, September 1998, and published in abstract form as Digestion 1998; 59: A5029. [ABSTRACT FROM AUTHOR]