828 results
Search Results
2. Digital consent to improve patient perception of shared decision-making: comparative study between paper and digital consent processes in patients undergoing breast surgery.
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St John, Edward Robert, Ezzat, Ahmed, Holford, Nicholas, Rizki, Hirah, Hogben, Katy, and Leff, Daniel Richard
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ELECTRONIC paper , *PATIENTS' attitudes , *BREAST surgery , *INFORMED consent (Medical law) , *COMPARATIVE studies , *DIGITAL mammography - Published
- 2022
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3. Short Papers.
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- 2021
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4. Short Papers.
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RESTORATIVE proctocolectomy , *SURGICAL site infections , *HYPONATREMIA , *MEDICAL personnel , *WILCOXON signed-rank test , *PATIENT reported outcome measures , *CHILD patients - Abstract
Only 8 patients (5.9%) had a new finding on second or subsequent visits (colonic polyp in 6 patients, renal cancer in one patient and benign adrenal adenoma in one patient). For patient with screen and surveillance detected AAA the median times from diagnosis to first clinic review was 8-days and 17-days; and from diagnosis to surgery 43-days (7 [59%] of patients were operated on within 40-days) and 76-days (only 20 [30%] of patients were operated on within 40-days) respectively. WS 6.3 Patient reported surgical site infection after elective colorectal surgery - patient reported... Lydia Newton, Ffion Dewi, Harry Dean, Cara Swain, Dawn Gane, Anne Pullyblank North Bristol NHS Trust Aims: 30-day surgical site infection (SSI) after colorectal resection is difficult to measure as patients are discharged quickly within enhanced recovery programmes. WS 13.3 Z-Plasty is an effective management for colostomy stenosis in high risk patients Judith Johnston, Mohamed Basheer Midyorkshire Hospital Trust Aims: To ascertain which patients are managed with Z-plasty for stomal stenosis To assess the effectiveness of using Z-plasty in treating stomal stenosis Methods: Operative information around all patients from 2010-2019 who underwent Z-plasty for stomal stenosis was collected and analysed on Excel. [Extracted from the article]
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- 2020
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5. Short Papers.
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DIVERTICULITIS , *ILEOSTOMY , *APPENDICITIS , *TIBIAL arteries , *MANN Whitney U Test , *FOURNIER gangrene , *COOLDOWN , *LOW-calorie diet - Abstract
Methods: Electronic patient records of 1088 patients who underwent ANC Patients had their USS the same day and 26% of patients had to return the Cases, 6 patients developed septicemia, 2 patients developed ARF, 2 patients Vital role in providing treatment services to patients, Patient reported outcome Timeline of each case from the time the patient was sent for till the patient goes. [Extracted from the article]
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- 2019
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6. Short Papers of Distinction.
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TREATMENT of hemorrhoids , *RANDOMIZED controlled trials , *PROCTOLOGY , *SURGICAL complications , *LAPAROSCOPY , *POSTOPERATIVE care - Published
- 2017
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7. Short Papers.
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FRAGILITY (Psychology) , *PATIENT readmissions , *OCTREOTIDE acetate , *SMALL intestine cancer , *CARCINOID , *THERAPEUTICS - Published
- 2017
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8. Short Papers.
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SURGERY , *LEGAL compliance , *HEMIARTHROPLASTY , *OPERATIVE surgery , *HIP joint - Abstract
Several abstracts are presented which includes one on Compliance Audit in Day Surgery Unit (DSU), the other on improving postoperative information transfer and the third on the use of "Hip Precautions" after hip hemiarthroplasty.
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- 2016
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9. Patey Prize Papers.
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VARICOSE veins , *OBESITY , *GENETIC polymorphisms - Abstract
The article presents abstracts of articles on surgery topics including one on the relationship between disease severity and Aberdeen varicose vein questionnaire (AVVQ), another on influence of obesity on insulin resistance, and the effects of genetic polymorphisms on aortic growth.
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- 2016
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10. Short papers.
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SOCIAL media in medicine , *TRAINING of medical students , *SURGICAL education - Abstract
Several abstracts are presented related to non-profit organization Association Of Surgeons Of Great Britain & Ireland (ASGBI) including analysis of surgical competence, using social media to share surgical evidence and using simulation with Frozen Cadaveric model for training medical students.
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- 2015
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11. ATMS - Oral Papers.
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MILITARY surgery , *ABDOMINAL surgery , *BLOOD filtration - Abstract
Several abstracts related to trauma and military surgery are presented including surgical options to control laparotomy, study on electrolyte variability in military trauma patients and psychological effects of extracorporeal hemofiltration in hind limb ischemia-reperfusion injury in Sus scrofa.
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- 2015
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12. Short Papers of Distinction.
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PERIOPERATIVE care , *OPERATIVE surgery , *AORTIC aneurysms - Abstract
Several abstracts related to perioperative care and clinical science are presented including effect of beta-blockade on physical fitness physical fitness in patients with abdominal aortic aneurysms, tumour pathology in Colorectal Cancer and study of surgical care in an African District Hospital.
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- 2015
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13. Short Papers of Distinction.
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APPENDICITIS , *SLEEP interruptions , *SLEEP-wake cycle , *RAPID eye movement sleep , *PATIENTS' rights , *SURGICAL emergencies - Abstract
Ambulatory Management of Right Iliac Fossa Pain: A Five-year Review Dale Thompson, Sarah Richards Royal United Hospitals, Bath Aim: Acute appendicitis is the most common indication for emergency surgery. The investigation and management of patients presenting with right iliac fossa (RIF) pain is usually on an in-patient basis in the UK. We present a 5-year experience of managing patients with RIF pain on an ambulatory basis in Emergency Surgical Ambulatory Care (ESAC). [Extracted from the article]
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- 2020
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14. Short Papers of Distinction.
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SERUM , *OSTEONECTIN , *MEDICAL screening , *PANCREATIC cancer , *PSYCHOLOGICAL stress - Abstract
Several abstracts on surgery are presented which includes one on the use of serum osteonectin for screening pancreatic cancer, the other on appendectomy and the third on post -traumatic stress disorder.
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- 2016
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15. Quickfire Papers.
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INTERMITTENT claudication , *INTERMITTENT claudication treatment , *THROMBOLYTIC therapy , *PATIENTS - Abstract
The article presents abstracts on medical topics which include prediction of autogenous Arterio-venous fistula maturity, a study on the use of pragmatic structured education programme to increase walking in people with intermittent claudication, and thrombolysis in vascular patients.
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- 2015
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16. Clinical Prize Papers - Wednesday.
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AORTIC aneurysms , *ULTRASONIC imaging , *SURGICAL stents - Abstract
The article presents abstracts on medical topics which include identification of abdominal aortic aneurysm, a study on implementation of dual anti-platelet therapy to reduce recurrent neurological events prior to surgery, and duplex ultrasound surveillance to maintain stent patency.
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- 2015
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17. Scientific Prize Papers.
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INTERMITTENT claudication treatment , *LYMPHEDEMA , *GLUCOSE transporters , *PATIENTS - Abstract
The article presents abstracts on medical topics which include risk associated with management of patients with intermittent claudication, a study on abdominal aortic aneurysms via modulation of glucose transporters, and analysis of human venous valve in patients with lymphoedema.
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- 2015
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18. Short Papers of Distinction.
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ESOPHAGOGASTRIC junction - Abstract
To FLOT chemotherapy in a cohort of patients treated with radical intent. Methods: Patients receiving perioperative FLOT for oesophagogastric ade- Chemotherapy-related toxicity was encountered in 6/24 (25%) patients Chemotherapy was completed in 9/17 (52.9%) patients. [Extracted from the article]
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- 2019
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19. Short Papers.
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ENDOSCOPIC surgery ,SURGICAL complications ,FUNDOPLICATION ,GASTRECTOMY ,MEDICAL care - Published
- 2018
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20. Surgery for advanced neuroendocrine tumours of the small bowel: recommendations based on a consensus meeting of the European Society of Endocrine Surgeons (ESES).
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Van Den Heede, Klaas, van Beek, Dirk-Jan, Van Slycke, Sam, Borel Rinkes, Inne, Norlén, Olov, Stålberg, Peter, and Nordenström, Erik
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NEUROENDOCRINE tumors , *SMALL intestine , *LITERATURE reviews , *SURGEONS , *ENTEROSCOPY , *SURGICAL indications - Abstract
Background: Small bowel neuroendocrine tumours often present with locally advanced or metastatic disease. The aim of this paper is to provide evidence-based recommendations regarding (controversial) topics in the surgical management of advanced small bowel neuroendocrine tumours. Methods: A working group of experts was formed by the European Society of Endocrine Surgeons. The group addressed 11 clinically relevant questions regarding surgery for advanced disease, including the benefit of primary tumour resection, the role of cytoreduction, the extent of lymph node clearance, and the management of an unknown primary tumour. A systematic literature search was performed in MEDLINE to identify papers addressing the research questions. Final recommendations were presented and voted upon by European Society of Endocrine Surgeons members at the European Society of Endocrine Surgeons Conference in Mainz in 2023. Results: The literature review yielded 1223 papers, of which 84 were included. There were no randomized controlled trials to address any of the research questions and therefore conclusions were based on the available case series, cohort studies, and systematic reviews/meta-analyses of the available non-randomized studies. The proposed recommendations were scored by 38–51 members and rated 'strongly agree' or 'agree' by 64–96% of participants. Conclusion: This paper provides recommendations based on the best available evidence and expert opinion on the surgical management of locally advanced and metastatic small bowel neuroendocrine tumours. This paper provides evidence-based recommendations on the surgical management of locally advanced and metastatic small bowel neuroendocrine tumours, primary tumour resections in the setting of metastatic disease, and surgical indications for grade 3 small bowel neuroendocrine tumours and small bowel neuroendocrine carcinomas. The recommendations are the result of a working group of experts, created by the European Society of Endocrine Surgeons. The group addressed 11 relevant clinical questions regarding surgery for advanced disease, emphasizing and confirming the key role of the surgeon for advanced small bowel neuroendocrine tumours. [ABSTRACT FROM AUTHOR]
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- 2024
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21. Clinical Treatment Score post-5 years as a predictor of late distant recurrence in hormone receptor-positive breast cancer: systematic review and meta-analysis.
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Shrestha, Amber, Cullinane, Carolyn, Evoy, Denis, Geraghty, James, Rothwell, Jane, Walshe, Janice, McCartan, Damien, McDermott, Enda, and Prichard, Ruth
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HORMONE receptor positive breast cancer ,BREAST cancer ,HORMONE therapy ,CANCER patients ,DISEASE relapse ,HORMONES - Abstract
Background: The Clinical Treatment Score post-5 years (CTS5) integrates four clinicopathological variables to estimate the residual disease recurrence risk in hormone receptor-positive breast cancer patients who have been treated with five years of adjuvant endocrine therapy. This study aimed to determine the accuracy of the CTS5. Methods: A systematic review was performed in accordance with the PRISMA statement. Studies relevant for inclusion in the current review were identified from The Cochrane Library, EBSCO, Ovid, PubMed, and Embase. Results: Six papers reported on 30 354 postmenopausal patients (age range 42 to 91 years). The pooled hazard ratio (HR) of distant recurrence relative to the low-risk CTS5 category was 5.41 (95% c.i. 4.50 to 6.51; P,0.05) for the high-risk CTS5 category and 2.32 (95% c.i. 1.90-2.84; P,0.05) for the intermediate CTS5 category. Three papers reported on 10 425 premenopausal patients (age range 18 to 54 years). The pooled HR of distant recurrence relative to the low-risk CTS5 category was 5.42 (95% c.i. 2.26 to 13.01; P, 0.05) for the high-risk CTS5 category and 2.82 (95% c.i. 1.35 to 5.88; P,0.05) for the intermediate CTS5 category. Relative to highrisk postmenopausal patients, the mean observed 10-year distant recurrence risk for the high CTS5 category was 13.83 per cent, which differs significantly from the CTS5 estimation of 10-year distant recurrence risk (20.3 per cent, 95% c.i. 17.2 to 24; P=0.000). Conclusion: The CTS5 can predict late distant recurrence risk in pre- and postmenopausal hormone receptor-positive breast cancer patients. CTS5 overestimates the risk for high-risk patients and thus, its use in these patients warrants caution. [ABSTRACT FROM AUTHOR]
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- 2022
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22. Short Papers of Distinction.
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COLON cancer ,BIOMARKERS ,IMMUNOASSAY ,CIRCULATING tumor DNA ,MEDICAL screening - Published
- 2018
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23. Growing research in global surgery with an eye towards equity.
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Hedt‐Gauthier, B. L., Riviello, R., Nkurunziza, T., and Kateera, F.
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SURGERY ,MEDICAL care ,PATIENT safety ,SURGEONS ,MEDICAL ethics - Abstract
Background: Global surgery research is often generated through collaborative partnerships between researchers from both low‐ and middle‐income countries (LMICs) and high‐income countries (HICs). Inequitable engagement of LMIC collaborators can limit the impact of the research. Methods: This article describes evidence of inequities in the conduct of global surgery research and outlines reasons why the inequities in this research field may be more acute than in other global health research disciplines. The paper goes on to describe activities for building a collaborative research portfolio in rural Rwanda. Results: Inequities in global surgery research collaborations can be attributed to: a limited number and experience of researchers working in this field; time constraints on both HIC and LMIC global surgery researchers; and surgical journal policies. Approaches to build a robust, collaborative research portfolio in Rwanda include leading research trainings focused on global surgery projects, embedding surgical fellows in Rwanda to provide bidirectional research training and outlining all research products, ensuring that all who are engaged have opportunities to grow in capacities, including leading research, and that collaborators share opportunities equitably. Of the 22 published or planned papers, half are led by Rwandan researchers, and the research now has independent research funding. Conclusion: It is unacceptable to gather data from an LMIC without meaningful engagement in all aspects of the research and sharing opportunities with local collaborators. The strategies outlined here can help research teams build global surgery research portfolios that optimize the potential for equitable engagement. Power dynamics in the field of global surgery research lead to inequitable opportunities for researchers in low‐ and middle‐income countries. This paper describes the authors' own experiences in Rwanda, and outlines strategies to develop a strong global surgery research portfolio and fair partnerships. Probity is key [ABSTRACT FROM AUTHOR]
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- 2019
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24. Systematic review of the prevalence, impact and mitigating strategies for bullying, undermining behaviour and harassment in the surgical workplace.
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Halim, U. A. and Riding, D. M.
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BULLYING ,HARASSMENT ,AMUSEMENTS ,MEDLINE ,SPORTS - Abstract
Background: Bullying, undermining behaviour and harassment (BUBH) have been reported in entertainment, politics and sport. Such behaviours may also be common in surgery, and are frequently associated with poor patient care and inferior outcomes. The aim was to define the prevalence and impact of this behaviour in the international surgical workplace, and to explore counterstrategies. Methods: A systematic review was conducted by searching EMBASE, Medline, PsycINFO and the Cochrane Database of Systematic Reviews in August 2017. Original research studies (Oxford Centre for Evidence‐based Medicine levels 1–4) investigating the prevalence and impact of BUBH in surgery, and/or counterstrategies, were eligible for inclusion. The review was conducted in accordance with PRISMA guidelines. Results: Of 2692 papers, 32 were eligible for inclusion. Twenty‐two reported the prevalence of BUBH in surgery, 11 studied the impact of this behaviour and six investigated counterstrategies. Prevalence data showed that BUBH are common in the surgical workplace. Their impact can be profound, compromising mental health, reducing job satisfaction, and inducing suicidal ideation. Formal reporting systems were perceived as ineffective and even potentially harmful to victims. Conclusion: Bullying, undermining behaviour and harassment are highly prevalent within surgery, and extremely damaging to victims. There is little high‐quality research into counterstrategies, although professionalism training using simulated scenarios may be useful. [ABSTRACT FROM AUTHOR]
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- 2018
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25. Updated guideline for closure of abdominal wall incisions from the European and American Hernia Societies.
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Deerenberg, Eva B., Henriksen, Nadia A., Antoniou, George A., Antoniou, Stavros A., Bramer, Wichor M., Fischer, John P., Fortelny, Rene H., Gök, Hakan, Harris, Hobart W., Hope, William, Horne, Charlotte M., Jensen, Thomas K., Köckerling, Ferdinand, Kretschmer, Alexander, López-Cano, Manuel, Malcher, Flavio, Shao, Jenny M., Slieker, Juliette C., de Smet, Gijs H. J., and Stabilini, Cesare
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ABDOMINAL wall ,HERNIA ,SURGICAL site ,OPERATIVE surgery ,LAPAROSCOPIC surgery ,SUTURING - Abstract
Background: Incisional hernia is a frequent complication of abdominal wall incision. Surgical technique is an important risk factor for the development of incisional hernia. The aim of these updated guidelines was to provide recommendations to decrease the incidence of incisional hernia. Methods: A systematic literature search of MEDLINE, Embase, and Cochrane CENTRAL was performed on 22 January 2022. The Scottish Intercollegiate Guidelines Network instrument was used to evaluate systematic reviews and meta-analyses, RCTs, and cohort studies. The GRADE approach (Grading of Recommendations, Assessment, Development and Evaluation) was used to appraise the certainty of the evidence. The guidelines group consisted of surgical specialists, a biomedical information specialist, certified guideline methodologist, and patient representative. Results: Thirty-nine papers were included covering seven key questions, and weak recommendations were made for all of these. Laparoscopic surgery and non-midline incisions are suggested to be preferred when safe and feasible. In laparoscopic surgery, suturing the fascial defect of trocar sites of 10 mm and larger is advised, especially after single-incision laparoscopic surgery and at the umbilicus. For closure of an elective midline laparotomy, a continuous small-bites suturing technique with a slowly absorbable suture is suggested. Prophylactic mesh augmentation after elective midline laparotomy can be considered to reduce the risk of incisional hernia; a permanent synthetic mesh in either the onlay or retromuscular position is advised. Conclusion: These updated guidelines may help surgeons in selecting the optimal approach and location of abdominal wall incisions. [ABSTRACT FROM AUTHOR]
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- 2022
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26. Systematic review of the introduction and evaluation of magnetic augmentation of the lower oesophageal sphincter for gastro‐oesophageal reflux disease.
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Kirkham, E. N., Main, B. G., Jones, K. J. B., Blazeby, J. M., and Blencowe, N. S.
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HEARTBURN ,META-analysis ,SPHINCTERS ,PATIENT selection ,TRAINING of surgeons - Abstract
Copyright of British Journal of Surgery is the property of Oxford University Press / USA and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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- 2020
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27. Low mortality rate after emergency laparotomy in Australia is a reflection of its national surgical mortality audit influencing futile surgery.
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Pule, Lettie M., Kopunic, Helena, and Aitken, R. James
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DEATH rate , *ABDOMINAL surgery , *HOSPITAL mortality , *AUDITING , *MORTALITY - Abstract
Background: Australia's unique national surgical mortality audit has had a long-term focus on the avoidance of futile surgery. The 30-day mortality rate after emergency laparotomy in Australia is lower than in other countries. Early death (within 72 h) after emergency laparotomy may reflect futile surgery. This paper considers whether Australia's national mortality audit is the reason for its lower mortality rate after emergency laparotomy. Methods: Data were extracted from the Australia and New Zealand Emergency Laparotomy Audit--Quality Improvement (ANZELA-QI) from 2018 to 2022. The time elapsed from emergency laparotomy to death was determined for each patient. The cumulative daily mortality rate was calculated for the first 30 days and expressed as a proportion of all emergency laparotomies, and 30-day and inhospital mortality. Mortality data were compared with those in the only three similar overseas studies. The mortality rate after emergency laparotomy for patients who required but did not undergo surgery was calculated for each hospital. The proportion of patients with high-risk characteristics was compared with that in the National Emergency Laparotomy Audit (NELA). Results: Compared with overseas studies, there was a lower early (within 72 h) mortality rate in ANZELA-QI. Although the lower mortality rate in ANZELA-QI persisted to 30 days, there was a relative increase after 14 days that likely reflected known poor compliance with care standards. Australian patients had fewer high-risk characteristics than those in NELA. Conclusion: The present findings support the hypothesis that the lower mortality rate after emergency laparotomy in Australia is likely a consequence of its national mortality audit and the avoidance of futile surgery. [ABSTRACT FROM AUTHOR]
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- 2023
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28. Enhanced recovery after surgery recommendations for renal transplantation: guidelines.
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Tan, Jaimee H. S., Bhatia, Kailash, Sharma, Videha, Swamy, Mruthunjaya, van Dellen, David, Dhanda, Raman, and Khambalia, Hussein
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ENHANCED recovery after surgery protocol ,KIDNEY transplantation ,SURGERY practice ,KIDNEY surgery ,RANDOMIZED controlled trials ,LENGTH of stay in hospitals - Abstract
Background: Enhanced Recovery After Surgery (ERAS) protocols are now widely practiced in major surgery, improving postsurgical outcomes. Uptake of these programmes have been slow in kidney transplantation due to challenges in evaluating their safety and efficacy in this high-risk cohort. To date, there are no unified guidance and protocols specific to ERAS in kidney transplantation surgery. This paper aims to summarise current evidence in the literature and develop ERAS protocol recommendations for kidney transplantation recipients. Methods: PubMed, Cochrane, Embase and Medline databases were screened for studies relevant to ERAS protocols in kidney transplantation, up to August 2021. A secondary search was repeated for each ERAS recommendation to explore the specific evidence base available for each section of the protocol. Randomised controlled trials, case-control and cohort studies were included. The Grading of Recommendations, Assessment, Development and Evaluations (GRADE) framework was used to evaluate the quality of evidence available and recommendations. Results: We identified six eligible studies with a total of 1225 participants. All studies found a reduction in length of hospital stay without affecting readmission rates. The evidence behind specific pre-operative, intra-operative and post-operative interventions included in current ERAS protocols are reviewed and discussed. Conclusion: Compared to other surgical specialties, the evidence base for ERAS in kidney transplantation remains lacking, with further room for research and development. However, significant improvements to patient outcomes are already possible with application of the currently available evidence. This has shown that ERAS in kidney transplantation surgery is safe and feasible, with improved postoperative outcomes. [ABSTRACT FROM AUTHOR]
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- 2023
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29. More research needed in mesh hiatal hernia repair? Comment on Analatos et al. and trial sequential analysis.
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Tselos, Alexander P., Drake, Thomas M., and McLean, Kenneth A.
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HERNIA surgery ,HIATAL hernia ,SEQUENTIAL analysis - Published
- 2023
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30. Systematic review of treatment intensification using novel agents for chemoradiotherapy in rectal cancer.
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Clifford, R., Govindarajah, N., Parsons, J. L., Gollins, S., West, N. P., and Vimalachandran, D.
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RECTAL cancer ,CANCER treatment ,CANCER chemotherapy ,OXALIPLATIN ,MEDICAL care - Abstract
Background: With the well established shift to neoadjuvant treatment for locally advanced rectal cancer, there is increasing focus on the use of radiosensitizers to improve the efficacy and tolerability of radiotherapy. There currently exist few randomized data exploring novel radiosensitizers to improve response and it is unclear what the clinical endpoints of such trials should be. Methods: A qualitative systematic review was performed according to the PRISMA guidelines using preset search criteria across the PubMed, Cochrane and Scopus databases from 1990 to 2017. Additional results were generated from the reference lists of included papers. Results: A total of 123 papers were identified, of which 37 were included; a further 60 articles were obtained from additional referencing to give a total of 97 articles. Neoadjuvant radiosensitization for locally advanced rectal cancer using fluoropyrimidine‐based chemotherapy remains the standard of treatment. The oral derivative capecitabine has practical advantages over 5‐fluorouracil, with equal efficacy, but the addition of a second chemotherapeutic agent has yet to show a consistent significant efficacy benefit in randomized clinical assessment. Preclinical and early‐phase trials are progressing with promising novel agents, such as small molecular inhibitors and nanoparticles. Conclusion: Despite extensive research and promising preclinical studies, a definite further agent in addition to fluoropyrimidines that consistently improves response rate has yet to be found. Promising agents coming [ABSTRACT FROM AUTHOR]
- Published
- 2018
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31. Kees Dejong.
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Earnshaw, Jonothan
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- 2022
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32. Systematic review of the complications following isolated calf deep vein thrombosis.
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Garry, J., Duke, A., and Labropoulos, N.
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VENOUS thrombosis ,META-analysis ,PULMONARY embolism ,CLINICAL trials ,MEDICAL subject headings ,CINAHL database - Abstract
Background A large number of studies have examined the potential complications of calf deep vein thrombosis ( DVT). There is no consensus on when or how to treat patients to prevent these complications. This systematic review assessed the rate of proximal propagation, pulmonary embolism, major bleeding and recurrence in patients with isolated calf DVT. Methods Database searches of MEDLINE, the Cochrane Library, Scopus, CINAHL and Web of Science were undertaken along with extensive cross-referencing. Two independent reviewers screened the papers using stringent inclusion and exclusion criteria. Included studies were graded on six methodological standards. Data on propagation, pulmonary embolism, recurrence and major bleeding were abstracted. Results A total of 4261 papers were found; 15 met the inclusion criteria, including five randomized clinical trials and ten prospective cohort studies. The propagation rate to the popliteal vein or above was around 9 per cent and the rate of pulmonary embolism was close to 1·5 per cent. No studies found anticoagulant therapy to reduce the rate of adverse outcomes. Conclusion The literature on calf DVT is heterogeneous, limiting conclusions from data analysis. Adverse outcomes are infrequent and studies do not suggest that they are reduced by anticoagulation. [ABSTRACT FROM AUTHOR]
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- 2016
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33. Breast-conserving surgery in patients with Paget's disease.
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Helme, S., Harvey, K., and Agrawal, A.
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OSTEITIS deformans treatment ,TREATMENT of bone diseases ,BREAST surgery ,MASTECTOMY ,RADIOTHERAPY - Abstract
Background Paget's disease of the breast is a rare condition that is associated with underlying breast cancer in the majority of patients. The conventional treatment for Paget's disease has been mastectomy, but there is an increasing trend to consider breast-conserving surgery ( BCS) in selected patients. Owing to the uncommon nature of the disease, research studies tend to be small and retrospective. This systematic review presents the published evidence regarding BCS for patients with Paget's disease with a focus on patient selection and oncological safety. Methods A search of Ovid and PubMed databases was conducted to identify all papers published regarding BCS for Paget's disease. Results The search identified 172 papers of which 43 were clinically relevant. BCS is a safe alternative to mastectomy, provided a clear surgical margin is achieved and adjuvant radiotherapy used. However, patients with Paget's disease should be assumed to have underlying breast cancer, and these cancers tend to have poor biological profiles. When BCS is considered, careful preoperative investigation should be undertaken to identify the presence and extent of an underlying cancer. These cancers can be mammographically occult, multifocal or multicentric. Although the evidence is limited, there may be a role for MRI in selecting patients with Paget's disease for BCS. Conclusion Patients with Paget's disease are candidates for breast conservation with appropriate preoperative investigations. Oncological outcomes are equivalent to those of mastectomy if surgical margins are achieved and adjuvant radiotherapy is given. [ABSTRACT FROM AUTHOR]
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- 2015
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34. Systematic review and critical appraisal of the impact of acellular dermal matrix use on the outcomes of implant-based breast reconstruction.
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Potter, S., Browning, D., Savović, J., Holcombe, C., and Blazeby, J. M.
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MAMMAPLASTY ,CLINICAL trials ,BREAST surgery ,HUMAN anatomy ,META-analysis ,AUGMENTATION mammaplasty ,BREAST implants - Abstract
Background Acellular dermal matrix ( ADM) may improve outcomes in implant-based breast reconstruction ( IBBR). The aim of this study was critically to appraise and evaluate the current evidence for ADM-assisted IBBR. Methods Comprehensive electronic searches identified complete papers published in English between January 2000 and August 2013, reporting any outcome of ADM-assisted IBBR. All systematic reviews, randomized clinical trials ( RCTs) and non-randomized studies ( NRSs) with more than 20 ADM recipients were included. Studies were critically appraised using AMSTAR for systematic reviews, the Cochrane risk-of-bias tool for RCTs and its adaptation for NRSs. Characteristics and results of identified studies were summarized. Results A total of 69 papers (8 systematic reviews, 1 RCT, 40 comparative studies and 20 case series) were identified, all of which were considered at high risk of bias, mostly due to patient selection and selective outcome reporting. The median ADM group sample size was 51.0 (i.q.r. 33.0-127.0). Most studies were single-centre (54), and they were often single-surgeon (16). ADM was most commonly used for immediate (40) two-stage IBBR (36) using human ADM (47), with few studies evaluating ADM-assisted single-stage procedures (10). All reported clinical outcomes (for example implant loss) and more than half of the papers (33) assessed process outcomes, but few evaluated cosmesis (16) or patient-reported outcomes (10). Heterogeneity between study design and, especially, outcome measurement precluded meaningful data synthesis. Conclusion Current evidence for the value of ADMs in IBBR is limited. Use in practice should therefore be considered experimental, and evaluation within registries or well designed and conducted studies, ideally RCTs, is recommended to prevent widespread adoption of a potentially inferior intervention. [ABSTRACT FROM AUTHOR]
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- 2015
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35. Breast Angiosarcoma Surveillance Study: UK national audit of management and outcomes of angiosarcoma of the breast and chest wall.
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Banks, J., George, J., Potter, S., Gardiner, M. D., Ives, C., Shaaban, A. M., Singh, J., Sherriff, J., Hallissey, M. T., Horgan, K., Harnett, A., Desai, A., Ferguson, D. J., Tillett, R., Izadi, D., Sadideen, H., Jain, A., Gerrand, C., Holcombe, C., and Hayes, A.
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ANGIOSARCOMA ,BREAST cancer ,SURVIVAL rate ,CANCER invasiveness ,CARCINOMA in situ ,DIAGNOSIS - Abstract
Background: Breast angiosarcomas are rare tumours of vascular origin. Secondary angiosarcoma occurs following radiotherapy for breast cancer. Angiosarcomas have high recurrence and poor survival rates. This is concerning owing to the increasing use of adjuvant radiotherapy for the treatment of invasive breast cancer and ductal cancer in situ (DCIS), which could explain the rising incidence of angiosarcoma. Outcome data are limited and provide a poor evidence base for treatment. This paper presents a national, trainee-led, retrospective, multicentre study of a large angiosarcoma cohort. Methods: Data for patients with a diagnosis of breast/chest wall angiosarcoma between 2000 and 2015 were collected retrospectively from 15 centres. Results: The cohort included 183 patients with 34 primary and 149 secondary angiosarcomas. Median latency from breast cancer to secondary angiosarcoma was 6 years. Only 78.9 per cent of patients were discussed at a sarcoma multidisciplinary team meeting. Rates of recurrence were high with 14 of 28 (50 per cent) recurrences in patients with primary and 80 of 124 (64.5 per cent) in those with secondary angiosarcoma at 5 years. Many patients had multiple recurrences: total of 94 recurrences in 162 patients (58.0 per cent). Median survival was 5 (range 0-16) years for patients with primary and 5 (0-15) years for those with secondary angiosarcoma. Development of secondary angiosarcoma had a negative impact on predicted breast cancer survival, with a median 10-year PREDICT prognostic rate of 69.6 per cent, compared with 54.0 per cent in the observed cohort. Conclusion: A detrimental impact of secondary angiosarcoma on breast cancer survival has been demonstrated. Although not statistically significant, almost all excess deaths were attributable to angiosarcoma. The increased use of adjuvant radiotherapy to treat low-risk breast cancer and DCIS is a cause for concern and warrants further study. [ABSTRACT FROM AUTHOR]
- Published
- 2021
- Full Text
- View/download PDF
36. Systematic review on reporting of components and outcomes in randomized clinical trials of paraoesophageal hernia mesh repair.
- Author
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Currie, A. C., Penney, N., Kamocka, A., Singh, P., Abbassi-Ghadi, N., and Preston, S. R.
- Subjects
CLINICAL trials ,TREATMENT effectiveness ,CLINICAL trial registries ,HERNIA ,FUNDOPLICATION - Abstract
Background: Surgical interventions, such as paraoesophageal hernia (POH) repair, are complex with multiple components that require consideration in the reporting of clinical trials. Many aspects of POH repair, including mesh hiatal reinforcement and fundoplication type, are contentious. This review summarizes the reporting of components and outcomes in RCTs of POH repair. Methods: Systematic searches identified RCTs of POH repair published from 1995 to 2020. The patient selection criteria for RCT involvement were noted. The components of the surgical interventions in these RCTs were recorded using the CONSORT guidelines for non-pharmacological treatments, Template for Intervention Description and Replication (TIDieR) and Blencowe frameworks. The outcomes were summarized and definitions sought for critical variables, including recurrence. Results: Of 1918 abstracts and 21 screened full-text articles, 12 full papers reporting on six RCTs were included in the review. The patient selection criteria and definitions of POH between trials varied considerably. Although some description of trial interventions was provided in all RCTs, this varied in depth and detail. Four RCTs described efforts to standardize the trial intervention. Outcomes were reported inconsistently, were rarely defined fully, and overall trial conclusions varied during follow-up. Conclusion: This lack of detail on the surgical intervention in POH repair RCTs prevents full understanding of what exact procedure was evaluated and how it should be delivered in clinical practice to gain the desired treatment effects. Improved focus on the definitions, descriptions and reporting of surgical interventions in POH repair is required for better future RCTs. [ABSTRACT FROM AUTHOR]
- Published
- 2021
- Full Text
- View/download PDF
37. Artificial intelligence and medical writing: where are we going?
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Fingerhut, Abe and Winter, Desmond C.
- Subjects
ARTIFICIAL intelligence ,MEDICAL writing - Published
- 2023
- Full Text
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38. This month on Twitter.
- Author
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Grossman, R. C.
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UMBILICAL hernia ,SURGICAL emergencies - Abstract
This month saw the release of both the January issue of I BJS i and the entirely free to access joint special issue on perioperative care with I Anaesthesia i journal. @NIHR GSU posted two interesting threads on global surgery, one sharing their favourite papers from the 2019 I BJS i special issue on the topic, including the GlobalSurg Collaborative paper on WHO Surgical Safety Checklist use and mortality after emergency laparotomy[7]. Guidelines for treatment of umbilical and epigastric hernias from the European Hernia Society and Americas Hernia Society. [Extracted from the article]
- Published
- 2020
- Full Text
- View/download PDF
39. Electronic personal assessment questionnaire for vascular conditions (ePAQ‐VAS): development and validity.
- Author
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Aber, A., Phillips, P., Hughes, J., Keetharuth, A. D., Rooney, G., Radley, S., Walters, S., Nawaz, S., Jones, G., and Michaels, J.
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INFORMATION services ,CONFIRMATORY factor analysis ,INTRACLASS correlation ,STATISTICAL reliability ,QUESTIONNAIRES - Abstract
Copyright of British Journal of Surgery is the property of Oxford University Press / USA and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2020
- Full Text
- View/download PDF
40. Three‐field versus two‐field lymphadenectomy in transthoracic oesophagectomy for oesophageal squamous cell carcinoma: short‐term outcomes of a randomized clinical trial.
- Author
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Li, B., Hu, H., Zhang, Y., Zhang, J., Miao, L., Ma, L., Luo, X., Ye, T., Li, H., Li, Y., Shen, L., Zhao, K., Fan, M., Zhu, Z., Wang, J., Xu, J., Deng, Y., Lu, Q., Pan, Y., and Liu, S.
- Subjects
LYMPHADENECTOMY ,SQUAMOUS cell carcinoma ,CLINICAL trials ,ESOPHAGECTOMY ,SURGICAL complications ,SURGICAL pathology - Abstract
Copyright of British Journal of Surgery is the property of Oxford University Press / USA and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2020
- Full Text
- View/download PDF
41. Perioperative care of the obese patient.
- Author
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Carron, M., Safaee Fakhr, B., Ieppariello, G., and Foletto, M.
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PERIOPERATIVE care ,MORBID obesity ,METABOLIC syndrome ,DIGITAL libraries ,ENGLISH language - Abstract
Copyright of British Journal of Surgery is the property of Oxford University Press / USA and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2020
- Full Text
- View/download PDF
42. Legal perspectives on black box recording devices in the operating environment.
- Author
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Dalen, A. S. H. M., Legemaate, J., Schlack, W. S., Legemate, D. A., and Schijven, M. P.
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MEDICAL personnel ,HEALTH insurance ,LEGAL literature ,PERSONALLY identifiable information ,DATA protection - Abstract
Copyright of British Journal of Surgery is the property of Oxford University Press / USA and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2019
- Full Text
- View/download PDF
43. Author response to: Intracorporeal versus extracorporeal anastomosis in laparoscopic right colectomy; earlier recovery, less complications, and more.
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Bollo, J. and Targarona, E. M.
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RIGHT hemicolectomy ,ELECTRONIC publications - Abstract
Emile's comments questioned the main outcome of our paper, selection of a process or clinical outcome I versus i a morbidity parameter. Intracorporeal anastomosis (IA) for laparoscopic right colectomy is not merely a technical option in anastomosis formation, it is a different surgical strategy. 4 Gomez M, Peralta G. A prospective observational multi-center 4 cohort study comparing robotic assisted and laparoscopic invasive right colectomy and intracorporeal anastomosis versus extracorporeal anastomosis. [Extracted from the article]
- Published
- 2020
- Full Text
- View/download PDF
44. Hiding behind 'innovation': the case for regulated risk assessment in surgery.
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Ives, Jonathan, Birchley, Giles, Huxtable, Richard, and Blazeby, Jane
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RISK assessment ,SURGERY - Published
- 2023
- Full Text
- View/download PDF
45. Tissue adhesive, adhesive tape, and sutures for skin closure of paediatric surgical wounds: prospective randomized clinical trial.
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Tandon, Sarthak, Ensor, Nicholas D., Pacilli, Maurizio, Laird, Ashleigh J., Bortagaray, Juan I., Stunden, Robert J., and Nataraja, Ramesh M.
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- *
SURGICAL site , *ADHESIVE tape , *CLINICAL trials , *SUTURES , *ADHESIVES , *PEDIATRICS - Abstract
Background: Tissue adhesive, adhesive tape, and sutures are used to close surgical incisions. However, it is unclear which produces the best results in children, and whether combination wound closure is better than sutures alone. Methods: In this parallel randomised controlled trial (ANZCTR: ACTRN12617000158369), children (aged 18 years or less) undergoing elective general surgical or urological procedures were randomized to skin closure with sutures alone, sutures and adhesive tape, or sutures and tissue adhesive. Participants were assessed 2 weeks, 6 weeks, and more than 6 months after operation. Outcomes included wound cosmesis (clinician- and parent-rated) assessed using four validated scales, parental satisfaction, and wound complication rates. Results: 295 patients (333 wounds) were recruited and 277 patients (314 wounds) were included in the analysis. Tissue adhesive wounds had poorer cosmesis at 6 weeks: median 10-point VAS score 7.7 with sutures alone, 7.5 with adhesive tape, and 7.0 with tissue adhesive (P=0.014). Respective median scores on a 100-point VAS were 80.0, 77.2, and 73.8 (P=0.010). This difference was not sustained at over 6 months. There was no difference in parent-rated wound cosmesis at 6 weeks (P=0.690) and more than 6 months (P=0.167): median score 9.0 with sutures alone, 10.0 with adhesive tape, and 10.0 with tissue adhesive at both stages. Parental satisfaction was similar at all points, with a median score of 5 (very satisfied) for all groups. There was one instance of wound dehiscence in the tissue adhesive group and no wound infections. Conclusion: Short-term wound cosmesis was poorer with tissue adhesive although it is unclear whether this difference is sustained in the long-term. There were no differences between techniques for the study outcomes. [ABSTRACT FROM AUTHOR]
- Published
- 2022
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- View/download PDF
46. As one door closes, another opens.
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Earnshaw, J. J.
- Subjects
PERIODICAL editors ,EDUCATIONAL programs ,MANUSCRIPTS ,OPEN access publishing ,SOCIAL media - Abstract
Welcome to BJS Open [ABSTRACT FROM AUTHOR]
- Published
- 2017
- Full Text
- View/download PDF
47. Waste not, want not: assessing the impact of arthroscopic waste.
- Author
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Shah, Siddharth, Morris, Holly, Nicolaou, Nic, MacInnes, Scott, Haslam, Paul, Shahane, Shantanu, Ali, Fazal, and Garcia, Joe
- Published
- 2023
- Full Text
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48. Evaluating the collection, comparability and findings of six global surgery indicators.
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Holmer, H., Bekele, A., Hagander, L., Harrison, E. M., Kamali, P., Ng‐Kamstra, J. S., Khan, M. A., Knowlton, L., Leather, A. J. M., Marks, I. H., Meara, J. G., Shrime, M. G., Smith, M., Søreide, K., Weiser, T. G., and Davies, J.
- Subjects
SURGERY ,ANESTHESIA ,SURGEONS ,MEDICAL care ,PATIENT safety - Abstract
Background: In 2015, six indicators were proposed to evaluate global progress towards access to safe, affordable and timely surgical and anaesthesia care. Although some have been adopted as core global health indicators, none has been evaluated systematically. The aims of this study were to assess the availability, comparability and utility of the indicators, and to present available data and updated estimates. Methods: Nationally representative data were compiled for all World Health Organization (WHO) member states from 2010 to 2016 through contacts with official bodies and review of the published and grey literature, and available databases. Availability, comparability and utility were assessed for each indicator: access to timely essential surgery, specialist surgical workforce density, surgical volume, perioperative mortality, and protection against impoverishing and catastrophic expenditure. Where feasible, imputation models were developed to generate global estimates. Results: Of all WHO member states, 19 had data on the proportion of the population within 2h of a surgical facility, 154 had data on workforce density, 72 reported number of procedures, and nine had perioperative mortality data, but none could report data on catastrophic or impoverishing expenditure. Comparability and utility were variable, and largely dependent on different definitions used. There were sufficient data to estimate that worldwide, in 2015, there were 2 038 947 (i.q.r. 1 884 916–2 281 776) surgeons, obstetricians and anaesthetists, and 266·1 (95 per cent c.i. 220·1 to 344·4) million operations performed. Conclusion: Surgical and anaesthesia indicators are increasingly being adopted by the global health community, but data availability remains low. Comparability and utility for all indicators require further resolution. This paper examines the availability, comparability and utility of six global surgery indicators. Surgical and anaesthesia indicators are increasingly being adopted by the global health community, but data availability remains low. Comparability and utility for all indicators require further resolution. An update, and a plea for improvement [ABSTRACT FROM AUTHOR]
- Published
- 2019
- Full Text
- View/download PDF
49. Systematic review of intervention design and delivery in pragmatic and explanatory surgical randomized clinical trials.
- Author
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Blencowe, N. S., Boddy, A. P., Harris, A., Hanna, T., Whiting, P., Cook, J. A., and Blazeby, J. M.
- Subjects
CLINICAL trials ,SURGERY ,PATIENT compliance ,OPERATIVE surgery ,SURGICAL complications - Abstract
Background Surgical interventions are complex, with multiple components that require consideration in trial reporting. This review examines the reporting of details of surgical interventions in randomized clinical trials ( RCTs) within the context of explanatory and pragmatic study designs. Methods Systematic searches identified RCTs of surgical interventions published in 2010 and 2011. Included studies were categorized as predominantly explanatory or pragmatic. The extent of intervention details in the reports were compared with the CONSORT statement for reporting trials of non-pharmacological treatments ( CONSORT-NPT). CONSORT-NPT recommends reporting the descriptions of surgical interventions, whether they were standardized and adhered to (items 4a, 4b and 4c). Reporting of the context of intervention delivery (items 3 and 15) and operator expertise (item 15) were assessed. Results Of 4541 abstracts and 131 full-text articles, 80 were included (of which 39 were classified as predominantly pragmatic), reporting 160 interventions. Descriptions of 129 interventions (80·6 per cent) were provided. Standardization was mentioned for 47 (29·4 per cent) of the 160 interventions, and 22 articles (28 per cent) reported measurement of adherence to at least one aspect of the intervention. Seventy-one papers (89 per cent) provided some information about context. For one-third of interventions (55, 34·4 per cent), some data were provided regarding the expertise of personnel involved. Reporting standards were similar in trials classified as pragmatic or explanatory. Conclusion The lack of detail in trial reports about surgical interventions creates difficulties in understanding which operations were actually evaluated. Methods for designing and reporting surgical interventions in RCTs, contributing to the quality of the overall study design, are required. This should allow better implementation of trial results into practice. [ABSTRACT FROM AUTHOR]
- Published
- 2015
- Full Text
- View/download PDF
50. Quantitative analysis of technological innovation in minimally invasive surgery.
- Author
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Hughes‐Hallett, A., Mayer, E. K., Pratt, P. J., Vale, J. A., and Darzi, A. W.
- Subjects
MEDICAL innovations ,LAPAROSCOPIC surgery ,SURGERY ,SURGERY practice ,SURGICAL equipment - Abstract
Background In the past 30 years surgical practice has changed considerably owing to the advent of minimally invasive surgery ( MIS). This paper investigates the changing surgical landscape chronologically and quantitatively, examining the technologies that have played, and are forecast to play, the largest part in this shift in surgical practice. Methods Electronic patent and publication databases were searched over the interval 1980-2011 for ('minimally invasive' OR laparoscopic OR laparoscopy OR 'minimal access' OR 'key hole') AND (surgery OR surgical OR surgeon). The resulting patent codes were allocated into technology clusters. Technology clusters referred to repeatedly in the contemporary surgical literature were also included in the analysis. Growth curves of patents and publications for the resulting technology clusters were then plotted. Results The initial search revealed 27 920 patents and 95 420 publications meeting the search criteria. The clusters meeting the criteria for in-depth analysis were: instruments, image guidance, surgical robotics, sutures, single-incision laparoscopic surgery ( SILS) and natural-orifice transluminal endoscopic surgery ( NOTES). Three patterns of growth were observed among these technology clusters: an S-shape (instruments and sutures), a gradual exponential rise (surgical robotics and image guidance), and a rapid contemporaneous exponential rise ( NOTES and SILS). Conclusion Technological innovation in MIS has been largely stagnant since its initial inception nearly 30 years ago, with few novel technologies emerging. The present study adds objective data to the previous claims that SILS, a surgical technique currently adopted by very few, represents an important part of the future of MIS. [ABSTRACT FROM AUTHOR]
- Published
- 2015
- Full Text
- View/download PDF
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