Search

Your search keyword '"Gabor A. Fulop"' showing total 1 results
Start Over Author "Gabor A. Fulop" Journal british journal of pharmacology
1 results on '"Gabor A. Fulop"'

1. The novel cardiac myosin activator omecamtiv mecarbil increases the calcium sensitivity of force production in isolated cardiomyocytes and skeletal muscle fibres of the rat

Author

István Édes, Enikő T. Pásztor, Nagy Laszlo, Beáta Bódi, Attila Tóth, Zoltán Papp, Árpád Kovács, and Gabor A. Fulop

Subjects
Pharmacology, Inotrope, medicine.medical_specialty, Chemistry, Activator (genetics), Cardiac myosin, Skeletal muscle, Isometric exercise, medicine.disease, Omecamtiv mecarbil, Endocrinology, medicine.anatomical_structure, Internal medicine, Heart failure, medicine, Calcium sensitivity
Abstract

Background and Purpose Omecamtiv mecarbil (OM) is a novel cardiac myosin activator drug for inotropic support in systolic heart failure. Here we have assessed the concentration-dependent mechanical effects of OM in permeabilized cardiomyocyte-sized preparations and single skeletal muscle fibres of Wistar-Kyoto rats under isometric conditions.

Published
2015
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results