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Your search keyword '"Arisbel B. Gondin"' showing total 2 results
Start Over Author "Arisbel B. Gondin" Journal british journal of pharmacology
2 results on '"Arisbel B. Gondin"'

2. Importance of receptor expression in the classification of novel ligands at the M

Author

Ye, Jiang, Mahmuda, Yeasmin, Arisbel B, Gondin, Arthur, Christopoulos, Celine, Valant, Wessel A C, Burger, and David M, Thal

Abstract

Affinity-based selective muscarinic acetylcholine receptor (mAChR) orthosteric ligands are difficult to develop due to high sequence homology across the five receptor subtypes. Selectivity can also be achieved via the selective activation of a particular subtype or signalling pathway. Promisingly, a prior study identified compounds 6A and 7A as functionally selective and GG protein activation was measured with the TRUPATH assay in MMThese data validate that the M

Published
2022

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