1. Early changes in photopic negative response in eyes with glaucoma with and without choroidal detachment after filtration surgery.
- Author
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Igawa, Yuro, Shoji, Takuhei, Miyake, Yozo, Yoshikawa, Yuji, Takano, Shunichiro, Shinoda, Kei, and Weinreb, Robert
- Subjects
Electrophysiology ,Glaucoma ,Treatment Surgery ,Humans ,Glaucoma ,Open-Angle ,Retrospective Studies ,Glaucoma ,Retinal Ganglion Cells ,Electroretinography ,Filtering Surgery ,Photic Stimulation - Abstract
BACKGROUND/AIMS: To evaluate the electroretinographic (ERG) changes in the early postoperative period following glaucoma filtration surgery, and its relationship with choroidal detachment (CD). METHODS: This retrospective observational single-centre study included 57 consecutive patients with primary open-angle glaucoma who underwent unilateral glaucoma filtration surgery. The patients were divided into two groups according to the presence or absence of CD. ERG components, including the photopic negative response (PhNR), a-wave and b-wave were compared before and after surgery using skin electrodes. RESULTS: There were 46 patients in the non-CD group and 11 in the CD group. ERG was recorded within 5.1 (2.1 to 8.1) (mean (95% CI)) days after surgery. In the non-CD group, the PhNR amplitude, PhNR/b-wave amplitude ratio and PhNR implicit time improved significantly after surgery (p=0.008, 0.002 and 0.039, respectively). In the CD group, the amplitude of the PhNR, a-wave and b-wave were significantly deteriorated after surgery (p=0.002, 0.001 and 0.001, respectively). Postoperative intraocular pressure (IOP) (p=0.031) and postoperative CD (p
- Published
- 2023