1. Haemolysis and Erythropoiesis
- Author
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H. Rodríguez‐Moyado, L. Espósito, L. Sánchez‐Medal, and J. Pizzuto
- Subjects
Adult ,Male ,Anemia, Hemolytic ,Reticulocytes ,Adolescent ,Reticulocytosis ,Physiology ,Folic Acid Deficiency ,Anemia, Hemolytic, Congenital ,Case records ,Reticulocyte ,Adrenal Cortex Hormones ,hemic and lymphatic diseases ,Haemolytic anaemias ,medicine ,Humans ,Erythropoiesis ,Vitamin B12 ,Child ,Aged ,Anemia, Hypochromic ,business.industry ,Infant ,Vitamin B 12 Deficiency ,Hematology ,Middle Aged ,Haemolysis ,medicine.anatomical_structure ,Child, Preschool ,Immunology ,Hemoglobinometry ,Female ,Anemia, Hemolytic, Autoimmune ,medicine.symptom ,business - Abstract
Summary. Case records of patients with anaemia due to lack of iron, vitamin B12 or folate, or to abnormal haemolysis were reviewed with regard to magnitude of reticulocytosis and rate of haemoglobin rise after therapy. Greater absolute reticulocyte values were observed in hereditary and acquired haemolytic anaemias. Furthermore, and more significantly, the rate of haemoglobin rise in autoimmune haemolytic anaemia responding to corticosteroid administration was greater than in the deficiency anaemias during adequate therapy. Additional data are presented supporting the old concept that erythrocytic production is greater in haemolytic anaemias than in deficiency anaemias after specific therapy.
- Published
- 1969
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