Author: "Claus Meyer" / Journal: british journal of haematology - Searchworks@Jio Institute Digital Library Search Results

Author: Rolf Marschalek, Valeria Iachelli, Luca Lo Nigro, Nellina Andriano, Paola Bonaccorso, Claus Meyer, and Manuela La Rosa
Subjects: Oncogene Proteins, biology, business.industry, Hematology, medicine.disease, 03 medical and health sciences, Leukemia, 0302 clinical medicine, KMT2A, Fusion transcript, 030220 oncology & carcinogenesis, Mutation (genetic algorithm), Acute myelomonocytic leukemia, medicine, Cancer research, biology.protein, business, Kras mutation, 030215 immunology
Published: 2018
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Author: Maria S. Pombo-de-Oliveira, Claus Meyer, Rolf Marschalek, Mariana Emerenciano, Bruno Almeida Lopes, and Thayana Conceição Barbosa
Subjects: biology, business.industry, Infant, Histone-Lysine N-Methyltransferase, Hematology, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Translocation, Genetic, Genes, ras, KMT2A, Mutation, Cancer research, biology.protein, Humans, Medicine, Lymphoblastic leukaemia, business, Myeloid-Lymphoid Leukemia Protein
Published: 2015
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Author: Marcela Braga Mansur, Mariana Emerenciano, Maria do Socorro Pombo-de-Oliveira, Rolf Marschalek, Claus Meyer, and Maria S. Pombo-de-Oliveira
Subjects: Male, Oncology, medicine.medical_specialty, Pediatrics, Myeloid, Chromosome Breakpoints, Biology, Disease-Free Survival, hemic and lymphatic diseases, Internal medicine, medicine, Humans, neoplasms, Survival rate, Breakpoint, Infant, Newborn, Infant, Histone-Lysine N-Methyltransferase, Hematology, Precursor Cell Lymphoblastic Leukemia-Lymphoma, medicine.disease, Introns, Survival Rate, Clinical trial, Leukemia, Myeloid, Acute, Leukemia, medicine.anatomical_structure, Child, Preschool, Cohort, Myeloid-Lymphoid Leukemia Protein, Female, Brazil
Abstract: Acute leukaemia in early childhood - and mainly infant leukaemia (IL) - is characterized by acquired genetic alterations, most commonly by the presence of distinct MLL rearrangements (MLL-r). The aim of this study was to investigate possible correlations between clinical features and molecular analyses of a series of 545 childhood leukaemia (≤24 months of age) cases: 385 acute lymphoblastic leukaemia (ALL) and 160 acute myeloid leukaemia (AML). The location of the genomic breakpoints was determined in a subset of 30 MLL-r cases. The overall survival of the investigated cohort was 60·5%, as determined by the Kaplan-Meier method. Worse outcomes were associated with age at diagnosis ≤6 months (P
Published: 2013
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Author: Patrick Duthilleul, Sabine Tricot, Aline Renneville, Agnès Daudignon, Stéphanie Poulain, Olivier Theisen, Rolf Marschalek, Charles Herbaux, Marc Simon, Jose Fernandes, and Claus Meyer
Subjects: Myeloid, Oncogene Proteins, business.industry, Chromosomal translocation, Hematology, Biology, medicine.disease, TOP3A, Histone-Lysine N-Methyltransferase, Leukemia, medicine.anatomical_structure, Text mining, medicine, Cancer research, business, Gene
Published: 2011
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Author: Susanna Fischer, Claus Meyer, Michael Dworzak, Margit König, Rolf Marschalek, E. Renate Panzer-Grümayer, Georg Mann, Oskar A. Haas, Andishe Attarbaschi, and Caroline Hutter
Subjects: medicine.medical_specialty, Hematology, Pre-B Lymphocyte, Cancer, Chromosomal translocation, Biology, medicine.disease, Pre-B-Cells, Precursor cell, Acute monocytic leukaemia, Internal medicine, Immunology, medicine, Cancer research, Monoblastic leukemia
Published: 2010
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Author: Marc De Braekeleer, Claude Férec, Claus Meyer, Etienne De Braekeleer, Rolf Marschalek, Nathalie Douet-Guilbert, Frédéric Morel, and Marie-Josée Le Bris
Subjects: Fusion gene, Text mining, Chromosomal Insertion, business.industry, Cancer research, FLNA, Hematology, Biology, Filamin, business, Gene
Published: 2009
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