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Start Over Author "Bernd Heinz" Journal british journal of haematology
5 results on '"Bernd Heinz"'

1. Tumour cell characteristics and microenvironment composition correspond to clinical presentation in newly diagnosed nodular lymphocyte‐predominant Hodgkin lymphoma

Author

Hartmann, Sylvia, primary, Soltani, Ahmad Sajad, additional, Bankov, Katrin, additional, Bein, Julia, additional, Hansmann, Martin‐Leo, additional, Rosenwald, Andreas, additional, Bernd, Heinz‐Wolfram, additional, Feller, Alfred, additional, Ott, German, additional, Möller, Peter, additional, Stein, Harald, additional, Klapper, Wolfram, additional, Borchmann, Peter, additional, Engert, Andreas, additional, and Eichenauer, Dennis A., additional

Published
2022
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2. Histopathological growth patterns in patients with advanced nodular lymphocyte‐predominant Hodgkin lymphoma treated within the randomized HD18 study: a report from the German Hodgkin Study Group

Author

Eichenauer, Dennis A., primary, Bühnen, Ina, additional, Kreissl, Stefanie, additional, Goergen, Helen, additional, Fuchs, Michael, additional, Tresckow, Bastian, additional, Rosenwald, Andreas, additional, Klapper, Wolfram, additional, Hansmann, Martin‐Leo, additional, Möller, Peter, additional, Bernd, Heinz‐Wolfram, additional, Feller, Alfred C., additional, Engert, Andreas, additional, Borchmann, Peter, additional, and Hartmann, Sylvia, additional

Published
2021
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3. Histopathological features and their prognostic impact in nodular lymphocyte-predominant Hodgkin lymphoma – a matched pair analysis from the German Hodgkin Study Group (GHSG)

Author

Hartmann, Sylvia, Eichenauer, Dennis A., Plütschow, Annette, Mottok, Anja, Bob, Roshanak, Koch, Karoline, Bernd, Heinz-Wolfram, Cogliatti, Sergio, Hummel, Michael, Feller, Alfred C., Ott, German, Möller, Peter, Rosenwald, Andreas, Stein, Harald, Hansmann, Martin-Leo, Engert, Andreas, and Klapper, Wolfram

Published
2014
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4. Histopathological growth patterns in patients with advanced nodular lymphocyte‐predominant Hodgkin lymphoma treated within the randomized HD18 study: a report from the German Hodgkin Study Group.

Author

Eichenauer, Dennis A., Bühnen, Ina, Kreissl, Stefanie, Goergen, Helen, Fuchs, Michael, von Tresckow, Bastian, Rosenwald, Andreas, Klapper, Wolfram, Hansmann, Martin‐Leo, Möller, Peter, Bernd, Heinz‐Wolfram, Feller, Alfred C., Engert, Andreas, Borchmann, Peter, and Hartmann, Sylvia

Subjects
HODGKIN'S disease, POSITRON emission tomography, HISTOPATHOLOGY, PROGRESSION-free survival, OVERALL survival, NEUROECTODERMAL tumors
Abstract

Summary: We retrospectively investigated histopathological growth patterns in individuals with advanced nodular lymphocyte‐predominant Hodgkin lymphoma (NLPHL) treated within the randomized HD18 study. In all, 35/60 patients (58%) presented with atypical growth patterns. Patients with atypical growth patterns more often had stage IV disease (P = 0·0354) and splenic involvement (P = 0·0048) than patients with typical growth patterns; a positive positron emission tomography after two cycles of chemotherapy (PET‐2) tended to be more common (P = 0·1078). Five‐year progression‐free survival [hazard ratio (HR) = 0·86; 95% confidence interval (CI) = 0·49–1·47] and overall survival (HR = 0·85; 95% CI = 0·49–1·51) did not differ between the groups after study treatment with PET‐2‐guided escalated BEACOPP (bleomycin, etoposide, doxorubicin, cyclophosphamide, vincristine, procarbazine, prednisone). Thus, advanced NLPHL is often associated with atypical growth patterns but their prognostic impact is compensated by PET‐2‐guided escalated BEACOPP. [ABSTRACT FROM AUTHOR]

Published
2022
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