1. Overweight, diabetes and disease duration influence clinical severity in hidradenitis suppurativa–acne inversa: evidence from the national Italian registry
- Author
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Vincenzo Bettoli, Luigi Naldi, Marzia Caproni, Stefania Zauli, Annarosa Virgili, Gabriella Fabbrocini, Beatrice Raone, M. Ricci, Simone Cazzaniga, Laura Atzori, C. Cardinali, Alessandro Borghi, Annalisa Patrizi, Riccardo Balestri, S. Pasquinucci, Al Pinna, R. Capezzera, V. Devita, Massimo Donini, A. Gimma, Bettoli, V., Naldi, L., Cazzaniga, S., Zauli, S., Atzori, L., Borghi, A., Capezzera, R., Caproni, M., Cardinali, C., Devita, V., Donini, M., Fabbrocini, Gabriella, Gimma, A., Pasquinucci, S., Patrizi, A., Pinna, A. L., Raone, B., Ricci, M., Virgili, A., Balestri, R., Fabbrocini, G., and Pinna, A.L.
- Subjects
Adult ,Male ,obesity ,skin ,medicine.medical_specialty ,Adolescent ,Demographics ,Disease duration ,Socio-culturale ,Dermatology ,Overweight ,smoking ,Young Adult ,030207 dermatology & venereal diseases ,03 medical and health sciences ,0302 clinical medicine ,Diabetes mellitus ,Acne Vulgaris ,Diabetes Mellitus ,Prevalence ,medicine ,Humans ,Hidradenitis suppurativa ,Clinical severity ,Registries ,030212 general & internal medicine ,Age of Onset ,Child ,610 Medicine & health ,Acne ,Aged ,Aged, 80 and over ,business.industry ,association ,hidradenitis suppurativa ,Middle Aged ,medicine.disease ,Cross-Sectional Studies ,Italy ,diabete ,clinical severity ,Female ,medicine.symptom ,business ,association, obesity, smoking, skin - Abstract
Hidradenitis suppurativa–acne inversa (HS-AI) is a chronic inflammatory skin condition that involves the folliculopilosebaceous units. Histopathological studies have suggested that the occlusion of the follicular infundibulum and both innate and adaptive immunity play central roles.1,2 Limited data regarding the clinical aspects and prognosis of HS-AI are available. Patients affected by HS-AI may benefit from early dietary interventions aimed at the metabolic comorbidities that may predispose the patient to HS-AI, reducing weight as a secondary benefit. The rationalization of preventive and therapeutic approaches among centres may help to harmonize the clinical management of HS-AI internationally, with a lasting benefit to patients.
- Published
- 2015