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This paper describes the occurrence in seven patients of localized ulceration of the lower lip due to the oral administration of various drugs. It is suggested that such ulcers achieve importance by affecting the same area of the lip in the same age group as squamous-cell carcinoma from which they must therefore be distinguished. [ABSTRACT FROM AUTHOR]

This article presents information on various papers related to dermatology. One of the papers discussed is "Basal-Cell Cancer in Children and Young Adults," by J.E. Murray and B. Cannon. In this paper, the histories of forty-one patients with basal-celled carcinoma are reviewed. All were under thirty years of age. In twelve cancer was diagnosed between sixteen and twenty years and in sixteen between twenty-six and thirty. In thirty-two there was a history of a previous lesion, usually a papilloma, naevus or scar, which was injured before cancer appeared. Another paper "The Ocular Complications of Chloroquine Therapy," by H.E. Hobbs and C.D. Calnan observed 30 patients under treatment with chloroquine.

The article presents information on a paper on carcinoma of the lip. The records of 182 patients with histologically proved squamous carcinoma of the lip were analyzed. Males predominated as usual, and when allowance was made for patients dying from other causes, there was an 80% survival rate without recurrence after five years.

The article presents information on the paper "Determinations of Squalene in Sebum From the Forehead of Patients with Skin Cancer," by H. Sobel, J. Makmorstan, E.T. Wright and E. Garcia that appeared in the 1957 issue of the "Journal of Investigative Dermatology." Squalene is supposed to neutralize the carcinogenic properties of methylcholanthrene. The normal secretion from the forehead is 1.4-7.3 mg per sq cm averaging 5.11 in 22 subjects. Eighteen patients with basal-celled growths averaged 10.58; while the 12 with squamous growths averaged only 2.86.

The article presents information on the research paper "The Action of Horse Serum on Sensitised Malignant Tissue." One patient had a punctate lymphogranulomatosis of skin and enlargement of glands mediastinal and other one had a spinulocellular carcinoma of the lower lip and adjacent area of skin. Photographs show the marked local anaphylactoid reaction that followed treatment of the lip lesion, the rapid reduction of swelling within 14 days, complete within a month and the excellent result when reviewed in 4 months.

This article focuses on the paper "The Aetiological Position of Sunlight in Skin Cancer," by H. Gratmann and E.-M. Reiners. This is an analysis of 24-73 cases of skin cancer. The authors found that epithelioma was commoner in rural male patients than urban ones. Epithelioma of the lower lip was commoner in rural patients and those urban ones more exposed to sunlight, than in town dwellers with indoor occupations. They consider that these types of skin cancer may have to be accepted as occupational diseases. There is no significant difference in basal-celled tumors and in the female.

The article focuses on the research paper "Scleroderma (Progressive Systemic Sclerosis), Associated With Cancer of the Lung," by S.M. Jonsson and J.M. Houser. The interesting feature in this report is the development of an adenocarcinoma of the lung in a woman aged 31, many years after the onset of scleroderma. The lesion appeared two months after treatment with cortisone was begun.

This article discusses the paper "Association of Mucocutaneous and Visceral Cancers," by Ervin Epstein. While admitting the difficulty of finding adequate controls for such a study the author concludes that internal cancer is not uncommon in patients with epitheliomas and that there is no evidence that epitheliomas immunize against visceral cancer.

The results of dermabrasion in 38 patients, all with epitheliomata and many with multiple lesions, are described. In treating superficial B.C.C. and Bowen's disease it is suggested that dermabrasion is the treatment of choice where it is readily available, being safe and simple and giving good cosmetic results. Dermabrasion may be a useful adjunct to other forms of treatment in cases of multiple keratoses and intraepidermal carcinoma occurring in association with solar dermatitis. [ABSTRACT FROM AUTHOR]

Report developments on the studies about dermatology from the Royal Society of Medicine in Great Britain. Identification chronic disseminated lupus erythematosus with lichenoid lesions at one case at St. George's Hospital; Approaches for treatment of dermatomyositis in a patient with a past history of carcinoma of the ovaries; Examinations the benign familial pemphigus.

Discusses the medical case of the patient with carcinoma erysipelatodes. Assessment of the physical condition of the patient upon diagnosis; Treatment options for the disease; Malignant changes undergone by the neoplastic cells in erysipelatodes.

The association of dermatomyositis with malignant disease is briefly reviewed, and all reported cases in the Bulgarian medical literature are listed. Of 18 cases of dermatomyositis investigated at the Plovdiv Clinic, 12 were over 40 years of age. Of these 50% had an associated carcinoma. In 1 the symptoms of dermatomyositis preceded by 3 years the discovery of the tumour. It is essential that any patient over 40 with dermatomyositis should be intensively and repeatedly investigated for the presence of malignant disease. [ABSTRACT FROM AUTHOR]