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Sarcoidosis is a multi-system disease of unknown aetiology characterised by the presence of non-caseating granulomas, the lungs and lymph nodes being the most affected sites. Orofacial manifestations of the condition are increasingly recognised, with several recent case reports where the initial presentation of the disease is in the region. Here, we report six cases of orofacial sarcoidosis which help to illustrate the wide spectrum of the condition.

Aim: The aim of this prospective study was to evaluate the morbidity at the donor site following harvest of chin bone for intra-oral augmentation., Method: The morbidity experienced by 27 consecutive patients who had undergone chin bone harvesting to augment intra-oral sites prior to implant placement at the Department of Oral and Maxillofacial Surgery, University Dental Hospital of Manchester was evaluated at one week, one, three and 12 months post-operatively., Results: Nine (33%) patients suffered post-operative morbidity. One patient experienced paraesthesia of the chin and lower lip and a further patient, paraesthesia of the gingivae immediately post-operatively. Both patients had full recovery when reviewed at three months. Two patients experienced pain at the graft site for up to three months post-operatively. Five (18.5%) patients experienced woodiness/numbness of the lower anterior teeth at the first post-operative visit and at 12 months, two patients continued to have no sensitivity in the lower anterior incisor teeth. None of the patients reported altered contour or change in profile of the chin area. Twenty-three (85.2%) patients had successful grafts with placement of implants thereafter., Conclusion: It is important for GDPs and specialists to make patients aware of the possible morbidities following harvest of bone from the chin.

Objective: To study the types of oral lesions in Thai heterosexual AIDS patients., Design: Cross-sectional study and single centre., Setting: Medical ward of the Prince of Songkla University Hospital, Thailand, from June 1994 to May 1995., Subjects: Heterosexual AIDS patients who had been admitted because of opportunistic infections and/or neoplasms., Main Outcome Measures: Types of oral lesions, opportunistic systemic diseases present and drugs in use, as well as the lymphocyte count, were recorded in each patient. Mycological investigations by the oral rinse technique were also performed., Results: 41 patients were examined (32 male, 9 female; aged 19-53 years, median 29 years). Oral lesions were found in 35 (85%) patients as follows: oral candidiasis (31), hairy leukoplakia (3), aphthous ulcer (3), linear gingival erythema (2), non-Hodgkin's lymphoma (2) and histoplasmosis (2). CANDIDA ALBICANS: was isolated in 31 patients. There was correlation between the clinical signs of oral candidiasis and the colony-forming units of Candida (Mann-Whitney U test; two-tailed P = 0.0007)., Conclusions: Oral candidiasis was the most common lesion. It is of interest that non-Hodgkin's lymphoma was the only neoplasm detected. We conclude that oral lesions among Thai heterosexual AIDS patients may differ from those in other countries.