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Start Over Author "Jordi Calderó" Journal brain pathology (zurich, switzerland)
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1. Accumulation of misfolded SOD1 outlines distinct patterns of motor neuron pathology and death during disease progression in a SOD1

Author

Sara, Salvany, Anna, Casanovas, Lídia, Piedrafita, Sílvia, Gras, Jordi, Calderó, and Josep E, Esquerda

Subjects
Motor Neurons, Mice, Disease Models, Animal, Superoxide Dismutase-1, Spinal Cord, Amyotrophic Lateral Sclerosis, Disease Progression, Animals, Mice, Transgenic, Proteostasis Deficiencies
Abstract

Early misfolded superoxide dismutase 1 (mfSOD1) accumulation, motor neuron (MN) degeneration, and microgliosis are hallmark pathological features in SOD1

Published
2021

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