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Start Over Author "Petterson T" Journal bone marrow transplantation
3 results on '"Petterson T"'

2. Outcome following unrelated cord blood transplant in 136 patients with malignant and non-malignant diseases: a report from the Australian and New Zealand children's haematology and oncology group

Author

Petterson, T E, primary, Gabriel, M, additional, Tiedemann, K, additional, Teague, L, additional, Shaw, P J, additional, Baker, D, additional, Bolton-Jones, R, additional, Tapp, H, additional, Oswald, C, additional, Vowels, M R, additional, and O'Brien, T A, additional

Published
2008
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3. High transplant-related mortality associated with haematopoietic stem cell transplantation for paediatric therapy-related acute myeloid leukaemia (t-AML). A study on behalf of the United Kingdom Paediatric Blood and Bone Marrow Transplant Group.

Author

Gassas A, Sivaprakasam P, Cummins M, Breslin P, Patrick K, Slatter M, Skinner R, Shenton G, Gibson B, Lawson S, Petterson T, Potter M, James B, Hough R, Hiwarkar P, Vora A, Veys P, De La Fuente J, Wynn R, and Amrolia P

Subjects
Adolescent, Antineoplastic Combined Chemotherapy Protocols therapeutic use, Bone Marrow Transplantation, Child, Child, Preschool, Cytarabine therapeutic use, Female, Granulocyte Colony-Stimulating Factor therapeutic use, Hematopoietic Stem Cell Transplantation mortality, Humans, Idarubicin therapeutic use, Male, Remission Induction methods, Salvage Therapy methods, Survival Analysis, United Kingdom, Vidarabine analogs & derivatives, Vidarabine therapeutic use, Hematopoietic Stem Cell Transplantation methods, Leukemia, Myeloid, Acute therapy, Neoplasms, Second Primary therapy
Abstract

Paediatric therapy-related acute myeloid leukaemia (t-AML) is rare and the outcome is poor. While allogeneic haematopoietic stem cell transplantation (HSCT) is generally the accepted modality of treatment, data regarding salvage chemotherapy, remission induction, conditioning regimens, transplant-related mortality and outcome is scarce. Between 2000 and2016, 36 children with t-AML were treated in seven UK paediatric HSCT centres. The most common salvage protocol for remission induction was FLAG with or without idarubicin and 28 patients were in complete morphological remission prior to BMT. Only 12 patients survived (33%). Transplant-related mortality (TRM) was the leading cause of death.

Published
2018
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