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Your search keyword '"Haupt, R"' showing total 13 results
Start Over Author "Haupt, R" Journal bone marrow transplantation
13 results on '"Haupt, R"'

12. Invasive mycoses in children receiving hemopoietic SCT.

Author

Castagnol, E., Faraci, M., Moroni, C., Bandettini, R., Granata, C., Caruso, S., Bagnasco, F., Caviglia, I., Malgorzata, M., Furfaro, E., Natalizia, A. R., de Fazio, V., Morreale, G., Lanino, E., Haupt, R., Dini, G., and Viscoli, C.

Subjects
MYCOSES, CHILDREN, TRANSPLANTATION of organs, tissues, etc., NEUTROPENIA, STEROIDS, GRAFT versus host disease, PEDIATRICS
Abstract

Invasive mycoses represent a rare but severe complication following hemopoietic SCT (HSCT) in children. Their incidence is related to the type of donor, being higher after allogeneic transplant, especially from alternative donors. Moreover, the incidence of invasive mycoses varies in the different post transplant phases. Neutropenia, lymphopenia, GvHD, high-dose steroids or other immunosuppressive drugs represent well-known risk factors. The clinical features of invasive mycoses after HSCT in children are similar to those observed in adults, and the diagnostic tools, including Aspergillus galactomannan antigen detection, are feasible also in pediatrics. Mortality due to invasive mycoses after HSCT in children is high.Bone Marrow Transplantation (2008) 41, S107–S111; doi:10.1038/bmt.2008.67 [ABSTRACT FROM AUTHOR]

Published
2008
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13. The polymorphisms-318C>T in the promoter and 49A>G in exon 1 of CTLA4 and the risk of aplastic anemia in a Caucasian population.

Author

Svahn, J, Capasso, M, Lanciotti, M, Marrone, A, Haupt, R, Bacigalupo, A, Pongiglione, C, Boschetto, L, Longoni, D, Pillon, M, Pistorio, A, Di Michele, P, Iori, A P, Calvillo, M, Locasciulli, A, Menna, G, Riccardi, R, Ramenghi, U, Dufour, C, and Iolascon, A

Subjects
ANEMIA, BLOOD diseases, AUTOIMMUNITY, APLASTIC anemia, AUTOIMMUNE diseases, BONE marrow transplantation
Abstract

SUMMARY::Aplastic anemia (AA) is a rare disease with a major autoimmune pathogenetic component. CTLA4 is a T-lymphocyte surface molecule involved in the maintenance of immune tolerance. Some polymorphisms associated with a reduced expression of CTLA4, and thus presumably with increased tendency to autoimmunity, have been associated with various autoimmune diseases. In this study, we evaluated the distribution of the low expression polymorphisms-318C>T and 49A>G of CTLA4 in a population of 67 patients with acquired AA and in 100 normal controls. There was no difference in the distribution of the tested polymorphism between patients and controls and, within the patient group, between those who responded to immunosuppression vs those who did not respond. This study indicates that the polymorphisms-318C>T and 49A>G of CTLA4 do not affect the risk of developing AA and do not influence the response to immunosuppression.Bone Marrow Transplantation (2005) 35, S89-S92. doi:10.1038/sj.bmt.1704855 [ABSTRACT FROM AUTHOR]

Published
2005
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