1. Geographic and other determinants of BMD change in European men and women at the hip and spine. a population-based study from the Network in Europe for Male Osteoporosis (NEMO)
- Author
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C.C. Glueer, Christa Scheidt-Nave, M Naves Díaz, Stephen Kaptoge, Jan J. Stepan, Huib A.P. Pols, David M. Reid, L. I. Benevolenskaya, Gyula Poór, K-T Khaw, J. Cannata, R. Eastell, JM Kaufman, Jonathan Reeve, Dieter Felsenberg, Nicola Crabtree, Steven Boonen, and Internal Medicine
- Subjects
musculoskeletal diseases ,Male ,medicine.medical_specialty ,Histology ,Physiology ,Endocrinology, Diabetes and Metabolism ,Osteoporosis ,Weight Gain ,Absorptiometry, Photon ,Sex Factors ,Bone Density ,Bayesian multivariate linear regression ,Surveys and Questionnaires ,Medicine and Health Sciences ,medicine ,Humans ,Femur ,Risk factor ,Rachis ,Femoral neck ,Aged ,Aged, 80 and over ,Hip ,Lumbar Vertebrae ,Trochanter ,business.industry ,Body Weight ,Age Factors ,Middle Aged ,medicine.disease ,Spine ,Osteopenia ,Europe ,medicine.anatomical_structure ,Physical therapy ,Female ,medicine.symptom ,business ,Weight gain ,Demography - Abstract
INTRODUCTION: While the determinants of BMD change have been studied in women, there have been few longitudinal studies in men. As part of the Network in Europe for Male Osteoporosis (NEMO) study, data were analysed from 1337 men and 1722 women aged 50-86y (mean=67 years) from 13 centres across Europe to assess determinants of BMD change and between-gender contrasts. METHODS: BMD was measured at the femoral neck, trochanter and/or L2-L4 spine on 2 occasions 0.8-8 years apart (mean=3.5 years) using DXA densitometers manufactured by Hologic (n=6), Lunar (n=5) and Norland (n=2). Each was cross-calibrated using the European Spine Phantom and annual rates of BMD change (g/cm(2)/year) were calculated from the standardised paired BMD values. The EPOS risk factor questionnaire was administered at baseline. RESULTS: In multivariate linear regression models, there were large between centre differences in the mean rates of BMD change in all 3 sites for both genders (P
- Published
- 2006