6 results on '"Rowett, Debra"'
Search Results
2. Risk of opioid misuse in people with cancer and pain and related clinical considerations: a qualitative study of the perspectives of Australian general practitioners
- Author
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Luckett, Tim, primary, Newton-John, Toby, additional, Phillips, Jane, additional, Holliday, Simon, additional, Giannitrapani, Karleen, additional, Powell-Davies, Gawaine, additional, Lovell, Melanie, additional, Liauw, Winston, additional, Rowett, Debra, additional, Pearson, Sallie-Anne, additional, Raymond, Bronwyn, additional, Heneka, Nicole, additional, and Lorenz, Karl, additional
- Published
- 2020
- Full Text
- View/download PDF
3. Use of a patient-centred educational exchange (PCEE) to improve patient’s self-management of medicines after a stroke: a randomised controlled trial study protocol
- Author
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Coombes, Judith Ann, primary, Rowett, Debra, additional, Whitty, Jennifer A, additional, and Cottrell, W Neil, additional
- Published
- 2018
- Full Text
- View/download PDF
4. Reducing medicine-induced deterioration and adverse reactions (ReMInDAR) trial: study protocol for a randomised controlled trial in residential aged-care facilities assessing frailty as the primary outcome
- Author
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Luke Bereznicki, Stacey Torode, Mackenzie Williams, André Queiroz de Andrade, Ai Choo Kang, Megan Corlis, Rebecca Bilton, Renly Lim, Lisa M. Kalisch Ellett, Joseph Whitehouse, Elizabeth E. Roughead, Gaynor Parfitt, Tracy Merlin, JM Cousins, Debra Rowett, Lan Kelly, Camille Schubert, Nicole L. Pratt, Lim, Renly, Bereznicki, Luke, Corlis, Megan, Kalisch Ellett, Lisa M, Kang, Ai Choo, Merlin,Tracy, Parfitt, Gaynor, Pratt, Nicole L, Rowett, Debra, Torode, Stacey, Whitehouse, Joseph, Andrade, Andre Q, Bilton, Rebecca, Cousins, Justin, Kelly, Lan, Schubert, Camille, Williams, Mackenzie, and Roughead, Elizabeth Ellen
- Subjects
cognition ,medicine.medical_specialty ,Time Factors ,Drug-Related Side Effects and Adverse Reactions ,medicine.drug_class ,Medication Therapy Management ,pharmacist ,Geriatric Medicine ,Pharmacist ,physical activity ,nursing homes ,Tasmania ,law.invention ,Grip strength ,Quality of life (healthcare) ,Randomized controlled trial ,law ,South Australia ,medicine ,Anticholinergic ,Homes for the Aged ,Humans ,Adverse effect ,Aged ,Protocol (science) ,Health Services Needs and Demand ,Clinical Deterioration ,Frailty ,Hand Strength ,business.industry ,Body Weight ,General Medicine ,Physical Functional Performance ,aged-care ,medicine-induced deterioration ,Emergency medicine ,Economic evaluation ,Polypharmacy ,Quality of Life ,adverse drug events ,business - Abstract
IntroductionMany medicines have adverse effects which are difficult to detect and frequently go unrecognised. Pharmacist monitoring of changes in signs and symptoms of these adverse effects, which we describe as medicine-induced deterioration, may reduce the risk of developing frailty. The aim of this trial is to determine the effectiveness of a 12-month pharmacist service compared with usual care in reducing medicine-induced deterioration, frailty and adverse reactions in older people living in aged-care facilities in Australia.Methods and analysisThe reducing medicine-induced deterioration and adverse reactions trial is a multicentre, open-label randomised controlled trial. Participants will be recruited from 39 facilities in South Australia and Tasmania. Residents will be included if they are using four or more medicines at the time of recruitment, or taking more than one medicine with anticholinergic or sedative properties. The intervention group will receive a pharmacist assessment which occurs every 8 weeks. The pharmacists will liaise with the participants’ general practitioners when medicine-induced deterioration is evident or adverse events are considered serious. The primary outcome is a reduction in medicine-induced deterioration from baseline to 6 and 12 months, as measured by change in frailty index. The secondary outcomes are changes in cognition scores, 24-hour movement behaviour, grip strength, weight, percentage robust, pre-frail and frail classification, rate of adverse medicine events, health-related quality of life and health resource use. The statistical analysis will use mixed-models adjusted for baseline to account for repeated outcome measures. A health economic evaluation will be conducted following trial completion using data collected during the trial.Ethics and disseminationEthics approvals have been obtained from the Human Research Ethics Committee of University of South Australia (ID:0000036440) and University of Tasmania (ID:H0017022). A copy of the final report will be provided to the Australian Government Department of Health.Trial registration numberAustralian and New Zealand Trials Registry ACTRN12618000766213.
- Published
- 2020
5. Risk of opioid misuse in people with cancer and pain and related clinical considerations: a qualitative study of the perspectives of Australian general practitioners
- Author
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Simon Holliday, Toby Newton-John, Winston Liauw, Melanie Lovell, Debra Rowett, Sallie-Anne Pearson, Karl A. Lorenz, Jane Phillips, Bronwyn Raymond, Tim Luckett, Karleen F. Giannitrapani, Gawaine Powell-Davies, Nicole Heneka, Luckett, Tim, Newton-John, Toby, Phillips, Jane, Holliday, Simon, Giannitrapani, Karleen, Powell-Davies, Gawaine, Lovell, Melanie, Liauw, Winston, Rowett, Debra, Pearson, Sallie Anne, Raymond, Bronwyn, Heneka, Nicole, and Lorenz, Karl
- Subjects
cancer pain ,medicine.medical_specialty ,Population ,Mindset ,Context (language use) ,Disease ,1103 Clinical Sciences, 1117 Public Health and Health Services, 1199 Other Medical and Health Sciences ,primary care ,General Practitioners ,Neoplasms ,medicine ,Humans ,Practice Patterns, Physicians' ,education ,Original Research ,education.field_of_study ,business.industry ,Australia ,Cancer ,General Medicine ,Opioid-Related Disorders ,medicine.disease ,Analgesics, Opioid ,pain management ,Opioid ,Family medicine ,Medicine ,Chronic Pain ,General practice / Family practice ,Cancer pain ,business ,qualitative research ,medicine.drug ,Qualitative research - Abstract
ObjectiveTo explore the perspectives of general practitioners (GPs) concerning the risk of opioid misuse in people with cancer and pain and related clinical considerations.DesignA qualitative approach using semistructured telephone interviews. Analysis used an integrative approach.SettingPrimary care.ParticipantsAustralian GPs with experience of prescribing opioids for people with cancer and pain.ResultsTwenty-two GPs participated, and three themes emerged. Theme 1 (Misuse is not the main problem) contextualised misuse as a relatively minor concern compared with pain control and toxicity, and highlighted underlying systemic factors, including limitations in continuity of care and doctor expertise. Theme 2 (‘A different mindset’ for cancer pain) captured participants’ relative comfort in prescribing opioids for pain in cancer versus non-cancer contexts, and acknowledgement that compassion and greater perceived community acceptance were driving factors, in addition to scientific support for mechanisms and clinical efficacy. Participant attitudes towards prescribing for people with cancer versus non-cancer pain differed most when cancer was in the palliative phase, when they were unconcerned by misuse. Participants were equivocal about the risk–benefit ratio of long-term opioid therapy in the chronic phase of cancer, and were reluctant to prescribe for disease-free survivors. Theme 3 (‘The question is always, ‘how lazy have you been?’) captured participants’ acknowledgement that they sometimes prescribed opioids for cancer pain as a default, easier option compared with more holistic pain management.ConclusionsFindings highlight the role of specific clinical considerations in distinguishing risk of opioid misuse in the cancer versus non-cancer population, rather than diagnosis per se. Further efforts are needed to ensure continuity of care where opioid prescribing is shared. Greater evidence is needed to guide opioid prescribing in disease-free survivors and the chronic phase of cancer, especially in the context of new treatments for metastatic disease.
- Published
- 2020
6. Use of a patient-centred educational exchange (PCEE) to improve patient's self-management of medicines after a stroke: a randomised controlled trial study protocol
- Author
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Jennifer A. Whitty, W. Neil Cottrell, Debra Rowett, Judith Coombes, Coombes, Judith Ann, Rowett, Debra, Whitty, Jennifer A, and Cottrell, W Neil
- Subjects
Adult ,Male ,medicine.medical_specialty ,Patient-Centred Medicine ,law.invention ,Medication Adherence ,Academic detailing ,03 medical and health sciences ,0302 clinical medicine ,Quality of life (healthcare) ,Randomized controlled trial ,Clinical Protocols ,Patient Education as Topic ,law ,Intervention (counseling) ,Patient-Centered Care ,Antithrombotic ,Secondary Prevention ,Protocol ,Medicine ,Humans ,030212 general & internal medicine ,adherence ,Stroke ,Protocol (science) ,Self-management ,business.industry ,Self-Management ,General Medicine ,medicine.disease ,stroke ,Family medicine ,stroke medicine ,Female ,medication ,academic detailing ,business ,secondary prevention ,030217 neurology & neurosurgery - Abstract
IntroductionNational and international guidelines make recommendations for secondary prevention of stroke including the use of medications. A strategy which engages patients in a conversation to personalise evidence-based educational material (patient-centred educational exchange; PCEE) may empower patients to better manage their medications.Methods and analysisThis protocol outlines a non-blinded randomised controlled trial. Consenting patients admitted with a diagnosis of stroke or transient ischaemic attack will be randomised 1:1 to receive either a PCEE composed of two sessions, one at the bedside before discharge and one by telephone at least 10 days after discharge from hospital in addition to usual care (intervention) or usual care alone (control). The primary aim of this study is to determine whether a PCEE improves adherence to antithrombotic, antihypertensive and lipid-lowering medications prescribed for secondary prevention of stroke over the 3 months after discharge, measured using prescription-refill data. Secondary aims include investigation of the impact of the PCEE on adherence over 12 months using prescription-refill data, self-reported medication taking behaviour, self-reported clinical outcomes (blood pressure, cholesterol, adverse medication events and readmission), quality of life, the cost utility of the intervention and changes in beliefs towards medicines and illness.Ethics and disseminationCommunication of the trial results will provide evidence to aid clinicians in conversations with patients about medication taking behaviour related to stroke prevention. The targeted audiences will be health practitioners and consumers interested in medication taking behaviour in chronic diseases and in particular those interested in secondary prevention of stroke.The trial has ethics approval from Metro South Human Research Ethics Committee (HREC/15/QPAH/531) and The University of Queensland Institutional Human Research Ethics (2015001612).Trial registration numberACTRN12615000888561; Pre-results.
- Published
- 2018
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