1. Impact of pulse oximetry screening on the detection of duct dependent congenital heart disease: a Swedish prospective screening study in 39,821 newborns.
- Author
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de-Wahl Granelli A, Wennergren M, Sandberg K, Mellander M, Bejlum C, Inganäs L, Eriksson M, Segerdahl N, Agren A, Ekman-Joelsson BM, Sunnegårdh J, Verdicchio M, and Ostman-Smith I
- Subjects
- False Positive Reactions, Heart Defects, Congenital epidemiology, Humans, Infant, Newborn, Physical Examination, Pilot Projects, Prospective Studies, Sweden epidemiology, Heart Defects, Congenital diagnosis, Neonatal Screening methods, Oximetry methods
- Abstract
Objective: To evaluate the use of pulse oximetry to screen for early detection of life threatening congenital heart disease., Design: Prospective screening study with a new generation pulse oximeter before discharge from well baby nurseries in West Götaland. Cohort study comparing the detection rate of duct dependent circulation in West Götaland with that in other regions not using pulse oximetry screening. Deaths at home with undetected duct dependent circulation were included., Setting: All 5 maternity units in West Götaland and the supraregional referral centre for neonatal cardiac surgery., Participants: 39,821 screened babies born between 1 July 2004 and 31 March 2007. Total duct dependent circulation cohorts: West Götaland n=60, other referring regions n=100., Main Outcome Measures: Sensitivity, specificity, positive and negative predictive values, and likelihood ratio for pulse oximetry screening and for neonatal physical examination alone., Results: In West Götaland 29 babies in well baby nurseries had duct dependent circulation undetected before neonatal discharge examination. In 13 cases, pulse oximetry showed oxygen saturations
- Published
- 2009
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