1. Filariasis presenting as pancytopenia in a child.
- Author
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Mandal AK, Jana JK, Gayen S, and Pal AC
- Subjects
- Albendazole therapeutic use, Animals, Child, Diethylcarbamazine therapeutic use, Drug Therapy, Combination, Female, Humans, Ivermectin therapeutic use, Wuchereria bancrofti, Elephantiasis, Filarial drug therapy, Filaricides therapeutic use, Pancytopenia drug therapy, Pancytopenia etiology
- Abstract
A female child hailing from South Asia, India presented with pallor, multiple petechiae and ecchymosis. Based on the clinical picture and demography, the differentials considered were pancytopenia of nutritional origin, acute leukaemia, autoimmune and infective aetiologies. After ruling these out by respective tests, a literature review was done which revealed the possibility of filariasis especially in a patient with eosinophilia which was present in our case. A repeat peripheral blood smear study with a nocturnally drawn sample revealed multiple microfilariae and a diagnosis of filariasis was made. The patient was treated with triple drug therapy of diethylcarbamazine (6 mg/kg), ivermectin (6 µg/kg) and albendazole (400 mg) administered as a single dose. Subsequent haemograms showed improved cell counts. This along with a previous handful of case reports emphasises filariasis as one of the differentials of pancytopenia and should be kept in mind while evaluating for the same, especially in the endemic areas., Competing Interests: Competing interests: None declared., (© BMJ Publishing Group Limited 2022. No commercial re-use. See rights and permissions. Published by BMJ.)
- Published
- 2022
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