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Start Over Author "Michiko Koda" Journal bmc women's health
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1. Safety and efficacy of Ninjin’yoeito along with iron supplementation therapy for preoperative anemia, fatigue, and anxiety in patients with gynecological disease: an open-label, single-center, randomized phase-II trial

Author

Taro Yagi, Kenjiro Sawada, Mayuko Miyamoto, Yasuto Kinose, Satoshi Nakagawa, Tsuyoshi Takiuchi, Michiko Kodama, Eiji Kobayashi, Kae Hashimoto, Seiji Mabuchi, Takuji Tomimatsu, Kiyoshi Yoshino, and Tadashi Kimura

Subjects
Anemia, Anxiety, Fatigue, Ferritin, Herbal medicine, Iron deficiency, Gynecology and obstetrics, RG1-991, Public aspects of medicine, RA1-1270
Abstract

Abstract Background Preoperative anemia affects perioperative outcomes and often causes fatigue and psychological disorders. Therefore, anemia should be treated before a patient undergoes surgery. Ninjin’yoeito (NYT), a Japanese Kampo medicine composed of ginseng and Japanese angelica root with the other 10 herbs, is administered for anemia, fatigue and anxiety; however, there are a few reports that have prospectively examined the effects of NYT before surgery for gynecological diseases. Hence, we tended to investigate its efficacy and safety. Methods In this open-label randomized trial, women with gynecological diseases accompanied by preoperative anemia (defined as

Published
2022
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