12 results on '"De Risio, Luisa"'
Search Results
2. Changes over time in craniocerebral morphology and syringomyelia in cavalier King Charles spaniels with Chiari-like malformation
- Author
-
Driver Colin J, De Risio Luisa, Hamilton Sarah, Rusbridge Clare, Dennis Ruth, McGonnell Imelda M, and Volk Holger A
- Subjects
Veterinary medicine ,SF600-1100 - Abstract
Abstract Background Chiari-like malformation (CM) and syringomyelia is a neurological disease complex with high prevalence in cavalier King Charles spaniels (CKCS). The natural progression of this disease with time has not been described. The objectives of this study were to i) determine if syringomyelia progresses with time ii) determine if features of craniocrebral morphology previously associated with CM are progressive (including caudal cranial fossa volume, caudal cranial fossa parenchymal volume, ventricular dimensions, height of the foramen magnum and degree of cerebellar herniation). A retrospective morphometric analysis was undertaken in 12 CKCS with CM for which repeat magnetic resonance images were available without surgical intervention. Results The maximal syrinx width, height of the foramen magnum, length of cerebellar herniation and caudal cranial fossa volume increased over time. Ventricular and caudal fossa parenchymal volumes were not significantly different between scans. Conclusions The results of this study suggest that syringomyelia progresses with time. Increased caudal cranial fossa volume may be associated with active resorption of the supraoccipital bone, which has previously been found in histology specimens from adult CKCS. We hypothesise that active resorption of the supraoccipital bone occurs due to pressure from the cerebellum. These findings have important implications for our understanding of the pathogenesis and variable natural clinical progression of CM and syringomyelia in CKCS.
- Published
- 2012
- Full Text
- View/download PDF
3. Inter-observer agreement of canine and feline paroxysmal event semiology and classification by veterinary neurology specialists and non-specialists
- Author
-
Packer, Rowena Ma, Berendt, Mette, Bhatti, Sofie, Charalambous, Marios, Cizinauskas, Sigitas, De Risio, Luisa, Farquhar, Robyn, Hampel, Rachel, Hill, Myfanwy, Mandigers, Paul Jj, Pakozdy, Akos, Preston, Stephanie M, Rusbridge, Clare, Stein, Veronika M, Taylor-Brown, Fran, Tipold, Andrea, Volk, Holger A, Sub Neurologie, CSCA AVM, Applied Veterinary Research, Sub Neurologie, CSCA AVM, and Applied Veterinary Research
- Subjects
Veterinary Medicine ,ABSENCE SEIZURES ,medicine.medical_specialty ,Neurology ,Veterinary neurology ,Inter observer agreement ,Movement ,Video Recording ,Audiology ,Autonomic Nervous System ,Cat Diseases ,Veterinarians ,Canine ,Agreement ,Feline ,Epilepsy ,Dogs ,Seizures ,Animals ,Medicine ,Veterinary Sciences ,Dog Diseases ,Psychiatry ,Event (probability theory) ,Observer Variation ,Paroxysmal event ,Behavior, Animal ,General Veterinary ,ILAE ,business.industry ,Video ,General Medicine ,Semiology ,medicine.disease ,veterinary(all) ,Seizure ,PREVALENCE ,KAPPA ,DOGS ,BIAS ,SEIZURE SEMIOLOGY ,Cats ,Epileptic seizure ,medicine.symptom ,business ,Kappa ,Research Article - Abstract
Background Advances in mobile technology mean vets are now commonly presented with videos of paroxysmal events by clients, but the consistency of the interpretation of these videos has not been investigated. The objective of this study was to investigate the level of agreement between vets (both neurology specialists and non-specialists) on the description and classification of videos depicting paroxysmal events, without knowing any results of diagnostic workup. An online questionnaire study was conducted, where participants watched 100 videos of dogs and cats exhibiting paroxysmal events and answered questions regarding: epileptic seizure presence (yes/no), seizure type, consciousness status, and the presence of motor, autonomic and neurobehavioural signs. Agreement statistics (percentage agreement and kappa) calculated for each variable, with prevalence indices calculated to aid their interpretation. Results Only a fair level of agreement (κ = 0.40) was found for epileptic seizure presence. Overall agreement of seizure type was moderate (κ = 0.44), with primary generalised seizures showing the highest level of agreement (κ = 0.60), and focal the lowest (κ =0.31). Fair agreement was found for consciousness status and the presence of autonomic signs (κ = 0.21–0.40), but poor agreement for neurobehavioral signs (κ = 0.16). Agreement for motor signs ranged from poor (κ = ≤ 0.20) to moderate (κ = 0.41–0.60). Differences between specialists and non-specialists were identified. Conclusions The relatively low levels of agreement described here highlight the need for further discussions between neurology experts regarding classifying and describing epileptic seizures, and additional training of non-specialists to facilitate accurate diagnosis. There is a need for diagnostic tools (e.g. electroencephalogram) able to differentiate between epileptic and non-epileptic paroxysms. Electronic supplementary material The online version of this article (doi:10.1186/s12917-015-0356-2) contains supplementary material, which is available to authorized users.
- Published
- 2015
4. Investigating the potential of the anti-epileptic drug imepitoin as a treatment for co-morbid anxiety in dogs with idiopathic epilepsy
- Author
-
Packer, Rowena M. A., primary, De Risio, Luisa, additional, and Volk, Holger A., additional
- Published
- 2017
- Full Text
- View/download PDF
5. International veterinary epilepsy task force consensus proposal: diagnostic approach to epilepsy in dogs
- Author
-
De Risio, Luisa, Bhatti, Sofie, Muñana, Karen, Penderis, Jacques, Stein, Veronika, Tipold, Andrea, Berendt, Mette, Farqhuar, Robyn, Fischer, Andrea, Long, Sam, Mandigers, Paul J J, Matiasek, Kaspar, Packer, Rowena M A, Pakozdy, Akos, Patterson, Ned, Platt, Simon, Podell, Michael, Potschka, Heidrun, Batlle, Martí Pumarola, Rusbridge, Clare, Volk, Holger A, Sub Neurologie, CSCA AVM, Applied Veterinary Research, Sub Neurologie, CSCA AVM, and Applied Veterinary Research
- Subjects
Veterinary Medicine ,Veterinary medicine ,Internationality ,Urinalysis ,Neurological examination ,Status epilepticus ,Electroencephalography ,INHERITANCE ,PLEOCYTOSIS ,CLASSIFICATION ,Epilepsy ,SYMPTOMATIC EPILEPSY ,Dogs ,CLINICAL CHARACTERISTICS ,Neuroimaging ,Correspondence ,Diagnosis ,Dog ,medicine ,Animals ,Genetic Predisposition to Disease ,Veterinary Sciences ,Dog Diseases ,General Veterinary ,medicine.diagnostic_test ,business.industry ,STATUS EPILEPTICUS ,HEAD TREMOR ,Idiopathic epilepsy ,Magnetic resonance imaging ,General Medicine ,medicine.disease ,veterinary(all) ,Seizure ,CEREBROSPINAL-FLUID ANALYSIS ,Practice Guidelines as Topic ,SEIZURES ,Epileptic seizure ,medicine.symptom ,business - Abstract
This article outlines the consensus proposal on diagnosis of epilepsy in dogs by the International Veterinary Epilepsy Task Force. The aim of this consensus proposal is to improve consistency in the diagnosis of epilepsy in the clinical and research settings. The diagnostic approach to the patient presenting with a history of suspected epileptic seizures incorporates two fundamental steps: to establish if the events the animal is demonstrating truly represent epileptic seizures and if so, to identify their underlying cause. Differentiation of epileptic seizures from other non-epileptic episodic paroxysmal events can be challenging. Criteria that can be used to make this differentiation are presented in detail and discussed. Criteria for the diagnosis of idiopathic epilepsy (IE) are described in a three-tier system. Tier I confidence level for the diagnosis of IE is based on a history of two or more unprovoked epileptic seizures occurring at least 24 h apart, age at epileptic seizure onset of between six months and six years, unremarkable inter-ictal physical and neurological examination, and no significant abnormalities on minimum data base blood tests and urinalysis. Tier II confidence level for the diagnosis of IE is based on the factors listed in tier I and unremarkable fasting and post-prandial bile acids, magnetic resonance imaging (MRI) of the brain (based on an epilepsy-specific brain MRI protocol) and cerebrospinal fluid (CSF) analysis. Tier III confidence level for the diagnosis of IE is based on the factors listed in tier I and II and identification of electroencephalographic abnormalities characteristic for seizure disorders. The authors recommend performing MRI of the brain and routine CSF analysis, after exclusion of reactive seizures, in dogs with age at epileptic seizure onset 6 years, inter-ictal neurological abnormalities consistent with intracranial neurolocalisation, status epilepticus or cluster seizure at epileptic seizure onset, or a previous presumptive diagnosis of IE and drug-resistance with a single antiepileptic drug titrated to the highest tolerable dose. This consensus article represents the basis for a more standardised diagnostic approach to the seizure patient. These recommendations will evolve over time with advances in neuroimaging, electroencephalography, and molecular genetics of canine epilepsy. Electronic supplementary material The online version of this article (doi:10.1186/s12917-015-0462-1) contains supplementary material, which is available to authorized users.
- Published
- 2015
6. International veterinary epilepsy task force consensus report on epilepsy definition, classification and terminology in companion animals
- Author
-
Berendt, Mette, Farquhar, Robyn G, Mandigers, Paul J J, Pakozdy, Akos, Bhatti, Sofie F M, De Risio, Luisa, Fischer, Andrea, Long, Sam, Matiasek, Kaspar, Muñana, Karen, Patterson, Edward E, Penderis, Jacques, Platt, Simon, Podell, Michael, Potschka, Heidrun, Pumarola, Martí Batlle, Rusbridge, Clare, Stein, Veronika M, Tipold, Andrea, Volk, Holger A, Sub Neurologie, CSCA AVM, Applied Veterinary Research, Sub Neurologie, CSCA AVM, and Applied Veterinary Research
- Subjects
Veterinary Medicine ,medicine.medical_specialty ,Veterinary medicine ,Internationality ,ELECTROENCEPHALOGRAPHIC FINDINGS ,LONG-TERM ,First line ,MEDLINE ,CANINE EPILEPSY ,INHERITANCE ,Terminology ,Semiology ,Epilepsy ,Dogs ,CLINICAL CHARACTERISTICS ,IDIOPATHIC EPILEPSY ,SEIZURE CLASSIFICATION ,Seizures ,Terminology as Topic ,Correspondence ,medicine ,Dog ,Animals ,Veterinary Sciences ,Dog Diseases ,General Veterinary ,business.industry ,Task force ,LABRADOR RETRIEVERS ,General Medicine ,Pets ,medicine.disease ,Classification ,veterinary(all) ,RISK-FACTORS ,SHEPHERD DOGS ,business ,International league against epilepsy - Abstract
Dogs with epilepsy are among the commonest neurological patients in veterinary practice and therefore have historically attracted much attention with regard to definitions, clinical approach and management. A number of classification proposals for canine epilepsy have been published during the years reflecting always in parts the current proposals coming from the human epilepsy organisation the International League Against Epilepsy (ILAE). It has however not been possible to gain agreed consensus, “a common language”, for the classification and terminology used between veterinary and human neurologists and neuroscientists, practitioners, neuropharmacologists and neuropathologists. This has led to an unfortunate situation where different veterinary publications and textbook chapters on epilepsy merely reflect individual author preferences with respect to terminology, which can be confusing to the readers and influence the definition and diagnosis of epilepsy in first line practice and research studies.\ud \ud In this document the International Veterinary Epilepsy Task Force (IVETF) discusses current understanding of canine epilepsy and presents our 2015 proposal for terminology and classification of epilepsy and epileptic seizures. We propose a classification system which reflects new thoughts from the human ILAE but also roots in former well accepted terminology. We think that this classification system can be used by all stakeholders.
- Published
- 2015
7. International Veterinary Epilepsy Task Force consensus proposal: medical treatment of canine epilepsy in Europe
- Author
-
Bhatti, Sofie F M, De Risio, Luisa, Muñana, Karen, Penderis, Jacques, Stein, Veronika M, Tipold, Andrea, Berendt, Mette, Farquhar, Robyn G, Fischer, Andrea, Long, Sam, Löscher, Wolfgang, Mandigers, Paul J J, Matiasek, Kaspar, Pakozdy, Akos, Patterson, Edward E, Platt, Simon, Podell, Michael, Potschka, Heidrun, Rusbridge, Clare, Volk, Holger A, Sub Neurologie, CSCA AVM, Applied Veterinary Research, Sub Neurologie, CSCA AVM, and Applied Veterinary Research
- Subjects
Drug ,Veterinary Medicine ,medicine.medical_specialty ,Veterinary medicine ,Veterinary Drugs ,Internationality ,ANTICONVULSANT DRUGS ,LONG-TERM ,media_common.quotation_subject ,MEDLINE ,Alternative medicine ,POTASSIUM-BROMIDE ,Epilepsy ,ANTIEPILEPTIC DRUG-THERAPY ,Dogs ,Correspondence ,REFRACTORY IDIOPATHIC EPILEPSY ,medicine ,Dog ,Animals ,Dog Diseases ,Veterinary Sciences ,Medical prescription ,media_common ,General Veterinary ,Medical treatment ,business.industry ,LABRADOR RETRIEVERS ,General Medicine ,medicine.disease ,veterinary(all) ,Europe ,Treatment ,THYROID-FUNCTION ,BORDER COLLIES ,Practice Guidelines as Topic ,Epileptic seizure ,ZONISAMIDE THERAPY ,RISK-FACTORS ,Anticonvulsants ,Thyroid function ,business - Abstract
In Europe, the number of antiepileptic drugs (AEDs) licensed for dogs has grown considerably over the last years. Nevertheless, the same questions remain, which include, 1) when to start treatment, 2) which drug is best used initially, 3) which adjunctive AED can be advised if treatment with the initial drug is unsatisfactory, and 4) when treatment changes should be considered. In this consensus proposal, an overview is given on the aim of AED treatment, when to start long-term treatment in canine epilepsy and which veterinary AEDs are currently in use for dogs. The consensus proposal for drug treatment protocols, 1) is based on current published evidence-based literature, 2) considers the current legal framework of the cascade regulation for the prescription of veterinary drugs in Europe, and 3) reflects the authors' experience. With this paper it is aimed to provide a consensus for the management of canine idiopathic epilepsy. Furthermore, for the management of structural epilepsy AEDs are inevitable in addition to treating the underlying cause, if possible.
- Published
- 2015
8. Prevalence, heritability and genetic correlations of congenital sensorineural deafness and coat pigmentation phenotype in the English bull terrier
- Author
-
De Risio, Luisa, primary, Freeman, Julia, additional, and Lewis, Thomas, additional
- Published
- 2016
- Full Text
- View/download PDF
9. International veterinary epilepsy task force consensus proposal: outcome of therapeutic interventions in canine and feline epilepsy
- Author
-
Potschka, Heidrun, primary, Fischer, Andrea, additional, Löscher, Wolfgang, additional, Patterson, Ned, additional, Bhatti, Sofie, additional, Berendt, Mette, additional, De Risio, Luisa, additional, Farquhar, Robyn, additional, Long, Sam, additional, Mandigers, Paul, additional, Matiasek, Kaspar, additional, Muñana, Karen, additional, Pakozdy, Akos, additional, Penderis, Jacques, additional, Platt, Simon, additional, Podell, Michael, additional, Rusbridge, Clare, additional, Stein, Veronika, additional, Tipold, Andrea, additional, and Volk, Holger A, additional
- Published
- 2015
- Full Text
- View/download PDF
10. International Veterinary Epilepsy Task Force recommendations for a veterinary epilepsy-specific MRI protocol
- Author
-
Rusbridge, Clare, primary, Long, Sam, additional, Jovanovik, Jelena, additional, Milne, Marjorie, additional, Berendt, Mette, additional, Bhatti, Sofie F. M., additional, De Risio, Luisa, additional, Farqhuar, Robyn G., additional, Fischer, Andrea, additional, Matiasek, Kaspar, additional, Muñana, Karen, additional, Patterson, Edward E., additional, Pakozdy, Akos, additional, Penderis, Jacques, additional, Platt, Simon, additional, Podell, Michael, additional, Potschka, Heidrun, additional, Stein, Veronika M., additional, Tipold, Andrea, additional, and Volk, Holger A., additional
- Published
- 2015
- Full Text
- View/download PDF
11. International veterinary epilepsy task force recommendations for systematic sampling and processing of brains from epileptic dogs and cats
- Author
-
Matiasek, Kaspar, primary, Pumarola i Batlle, Martí, additional, Rosati, Marco, additional, Fernández-Flores, Francisco, additional, Fischer, Andrea, additional, Wagner, Eva, additional, Berendt, Mette, additional, Bhatti, Sofie F. M., additional, De Risio, Luisa, additional, Farquhar, Robyn G., additional, Long, Sam, additional, Muñana, Karen, additional, Patterson, Edward E., additional, Pakozdy, Akos, additional, Penderis, Jacques, additional, Platt, Simon, additional, Podell, Michael, additional, Potschka, Heidrun, additional, Rusbridge, Clare, additional, Stein, Veronika M., additional, Tipold, Andrea, additional, and Volk, Holger A., additional
- Published
- 2015
- Full Text
- View/download PDF
12. International Veterinary Epilepsy Task Force's current understanding of idiopathic epilepsy of genetic or suspected genetic origin in purebred dogs.
- Author
-
Hülsmeyer, Velia-Isabel, Fischer, Andrea, Mandigers, Paul J. J., De Risio, Luisa, Berendt, Mette, Rusbridge, Clare, Bhatti, Sofie F. M., Pakozdy, Akos, Patterson, Edward E., Platt, Simon, Packer, Rowena M.A., and Volk, Holger A.
- Subjects
GENETICS of epilepsy ,EPILEPSY in animals ,DOG diseases ,VETERINARY therapeutics ,TREATMENT of epilepsy ,VETERINARY epidemiology - Abstract
Canine idiopathic epilepsy is a common neurological disease affecting both purebred and crossbred dogs. Various breed-specific cohort, epidemiological and genetic studies have been conducted to date, which all improved our knowledge and general understanding of canine idiopathic epilepsy, and in particular our knowledge of those breeds studied. However, these studies also frequently revealed differences between the investigated breeds with respect to clinical features, inheritance and prevalence rates. Awareness and observation of breed-specific differences is important for successful management of the dog with epilepsy in everyday clinical practice and furthermore may promote canine epilepsy research. The following manuscript reviews the evidence available for breeds which have been identified as being predisposed to idiopathic epilepsy with a proven or suspected genetic background, and highlights different breed specific clinical features (e.g. age at onset, sex, seizure type), treatment response, prevalence rates and proposed inheritance reported in the literature. In addition, certain breed-specific diseases that may act as potential differentials for idiopathic epilepsy are highlighted. [ABSTRACT FROM AUTHOR]
- Published
- 2015
- Full Text
- View/download PDF
Catalog
Discovery Service for Jio Institute Digital Library
For full access to our library's resources, please sign in.