1. Descriptive study of severe hospitalized cases of laboratory-confirmed influenza during five epidemic seasons (2010–2015)
- Author
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Tomás Pumarola, Sofia Minguell, Elsa Plasencia, Nuria Torner, Pere Godoy, Ana Martínez, Mónica Carol, Núria Follia, Luca Basile, Mireia Jané, M. R. Sala, Cristina Rius, MMar Mosquera, Marcelo Tacconi de Siqueira Marcos, Andrés Antón, Irene Barrabeig, and Universitat de Barcelona
- Subjects
0301 basic medicine ,Male ,Epidemiology ,lcsh:Medicine ,Vacunes ,0302 clinical medicine ,Influenza A Virus, H1N1 Subtype ,Medicine ,030212 general & internal medicine ,Child ,lcsh:QH301-705.5 ,Aged, 80 and over ,Vaccines ,Surveillance ,Antiviral drugs ,General Medicine ,Middle Aged ,Icu admission ,Vaccination ,Hospitalization ,Research Note ,Child, Preschool ,Female ,Adult ,medicine.medical_specialty ,Adolescent ,030106 microbiology ,Influenza epidemics ,Antiviral Agents ,General Biochemistry, Genetics and Molecular Biology ,Virus ,Grip ,03 medical and health sciences ,Young Adult ,Pharmacotherapy ,Internal medicine ,Influenza, Human ,Humans ,Epidemics ,Epidemiologia ,lcsh:Science (General) ,Viral isolation ,Aged ,business.industry ,Influenza A Virus, H3N2 Subtype ,lcsh:R ,Infant ,Influenza ,Immunization ,lcsh:Biology (General) ,Spain ,business ,Sentinel Surveillance ,Vaccine ,lcsh:Q1-390 - Abstract
Objective The Plan of Information on Acute Respiratory Infections in Catalonia (PIDIRAC) included the surveillance of severe hospitalized cases of laboratory-confirmed influenza (SHCLCI) in 2009. The objective of this study was to determine the clinical, epidemiological and virological features of SHCLCI recorded in 12 sentinel hospitals during five influenza seasons. Results From a sample of SHCLCI recorded during the 5 influenza epidemics seasons from 2010–2011 to 2014–2015, Cases were confirmed by PCR and/or viral isolation in cell cultures from respiratory samples. A total of 1400 SHCLCI were recorded, 33% required ICU admission and 12% died. The median age of cases was 61 years (range 0–101 years); 70.5% were unvaccinated; 80.4% received antiviral treatment (in 79.6 and 24% of cases within 48 h after hospital admission and the onset of symptoms, respectively); influenza virus A [37.9% A (H1N1)pdm09, 29.3% A (H3N2)] was identified in 87.7% of cases. Surveillance of SHCLCI provides an estimate of the severity of seasonal influenza epidemics and the identification and characterization of at-risk groups in order to facilitate preventive measures such as vaccination and early antiviral treatment. Electronic supplementary material The online version of this article (10.1186/s13104-018-3349-y) contains supplementary material, which is available to authorized users.
- Published
- 2018