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Your search keyword '"IgG avidity"' showing total 3 results
3 results on '"IgG avidity"'

1. Seroepidemiological study of toxoplasmosis in women referred to a pre-marriage counseling center in Alborz Province, Iran

Author

Melica Shahighi, Aliehsan Heidari, Hossein Keshavarz, Amir Bairami, Saeedeh Shojaee, Monireh Sezavar, Mahboobeh Salimi, and Aref Teimouri

Subjects
Toxoplasmosis, Women, IgG avidity, ELISA, PCR, Iran, Medicine, Biology (General), QH301-705.5, Science (General), Q1-390
Abstract

Abstract Objectives The aim of the current study was to assess prevalence of Toxoplasma infection and its associated risk factors in women of childbearing-age in central Iran. Results Of 400 serum samples assessed for anti-T. gondii antibodies, 81 (20.25%) samples were positive for anti-T. gondii antibodies, including 74 positive samples (91.3%) for anti-T. gondii IgG and seven positive samples (8.7%) for IgG and IgM. Of seven IgG and IgM positive samples, five and two samples were high and low in IgG avidity, respectively. Based on PCR analysis, Toxoplasma infection was detected in one sample with anti-T. gondii IgM and low IgG avidity. The Chi-square test showed significant correlations of T. gondii seropositivity with history of undercooked meat consumption and contacts with cats (p

Published
2021
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2. Seroepidemiological study of toxoplasmosis in women referred to a pre-marriage counseling center in Alborz Province, Iran.

Author

Shahighi, Melica, Heidari, Aliehsan, Keshavarz, Hossein, Bairami, Amir, Shojaee, Saeedeh, Sezavar, Monireh, Salimi, Mahboobeh, and Teimouri, Aref

Subjects
*IMMUNOGLOBULIN G, *COUNSELING, *CHI-squared test, *CHILDBEARING age, *TOXOPLASMOSIS
Abstract

Objectives: The aim of the current study was to assess prevalence of Toxoplasma infection and its associated risk factors in women of childbearing-age in central Iran. Results: Of 400 serum samples assessed for anti-T. gondii antibodies, 81 (20.25%) samples were positive for anti-T. gondii antibodies, including 74 positive samples (91.3%) for anti-T. gondii IgG and seven positive samples (8.7%) for IgG and IgM. Of seven IgG and IgM positive samples, five and two samples were high and low in IgG avidity, respectively. Based on PCR analysis, Toxoplasma infection was detected in one sample with anti-T. gondii IgM and low IgG avidity. The Chi-square test showed significant correlations of T. gondii seropositivity with history of undercooked meat consumption and contacts with cats (p < 0.05). In the present study, 79.75% of the participants were negative for IgG against T. gondii infection. Furthermore, recently acquired Toxoplasma infection was found using IgG avidity and PCR assays among women of childbearing-age in the study area, which would increase the risk of their fetus becoming infected. Educational program and antenatal screening of childbearing-age women for T. gondii infection may be important primary prevention strategies and help reduce the risk of congenital toxoplasmosis in this population. [ABSTRACT FROM AUTHOR]

Published
2021
Full Text
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3. Seroepidemiological study of toxoplasmosis in women referred to a pre-marriage counseling center in Alborz Province, Iran

Author

Aref Teimouri, Hossein Keshavarz, Mahboobeh Salimi, Amir Bairami, Saeedeh Shojaee, Melica Shahighi, Aliehsan Heidari, and Monireh Sezavar

Subjects
Counseling, 0301 basic medicine, Science (General), Antibodies, Protozoan, Iran, Q1-390, 0302 clinical medicine, Pregnancy, Seroepidemiologic Studies, Antenatal screening, Medicine, Marriage, Biology (General), Pcr analysis, education.field_of_study, biology, General Medicine, Research Note, PCR, Female, ELISA, Antibody, Toxoplasma, Toxoplasmosis, QH301-705.5, 030106 microbiology, 030231 tropical medicine, Population, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, parasitic diseases, Animals, Humans, Women, education, Fetus, business.industry, Igg avidity, Serum samples, medicine.disease, Immunoglobulin M, Immunoglobulin G, Immunology, Cats, IgG avidity, biology.protein, business
Abstract

Objectives The aim of the current study was to assess prevalence of Toxoplasma infection and its associated risk factors in women of childbearing-age in central Iran. Results Of 400 serum samples assessed for anti-T. gondii antibodies, 81 (20.25%) samples were positive for anti-T. gondii antibodies, including 74 positive samples (91.3%) for anti-T. gondii IgG and seven positive samples (8.7%) for IgG and IgM. Of seven IgG and IgM positive samples, five and two samples were high and low in IgG avidity, respectively. Based on PCR analysis, Toxoplasma infection was detected in one sample with anti-T. gondii IgM and low IgG avidity. The Chi-square test showed significant correlations of T. gondii seropositivity with history of undercooked meat consumption and contacts with cats (p T. gondii infection. Furthermore, recently acquired Toxoplasma infection was found using IgG avidity and PCR assays among women of childbearing-age in the study area, which would increase the risk of their fetus becoming infected. Educational program and antenatal screening of childbearing-age women for T. gondii infection may be important primary prevention strategies and help reduce the risk of congenital toxoplasmosis in this population.

Published
2021

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