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Start Over Author "Rivas‐Ruiz, Francisco" Journal bmc public health
4 results on '"Rivas‐Ruiz, Francisco"'

1. Geographic variability of fatal road traffic injuries in Spain during the period 2002–2004: an ecological study

Author

Jimenez-Puente Alberto, Perea-Milla Emilio, and Rivas-Ruiz Francisco

Subjects
Public aspects of medicine, RA1-1270
Abstract

Abstract Background The aim of the present study is to describe the inter-province variability of Road Traffic Injury (RTI) mortality on Spanish roads, adjusted for vehicle-kilometres travelled, and to assess the possible role played by the following explicative variables: sociodemographic, structural, climatic and risk conducts. Methods An ecological study design was employed. The mean annual rate of RTI deaths was calculated for the period 2002–2004, adjusted for vehicle-kilometres travelled, in the 50 provinces of Spain. The RTI death rate was related with the independent variables described above, using simple and multiple linear regression analysis with backward step-wise elimination. The level of statistical significance was taken as p < 0.05. Results In the period 2002–2004 there were 12,756 RTI deaths in Spain (an average of 4,242 per year, SD = 356.6). The mean number of deaths due to RTI per 100 million vehicle-kilometres (mvk) travelled was 1.76 (SD = 0.51), with a minimum value of 0.66 (in Santa Cruz de Tenerife) and a maximum of 3.31 (in the province of Lugo). All other variables being equal, a higher proportion of kilometres available on high capacity roads, and a higher cultural and education level were associated with lower death rates due to RTI, while the opposite was true for the rate of alcohol consumers and the road traffic volume of heavy vehicles. The variables included in the model accounted for 55.4% of the variability in RTI mortality. Conclusion Adjusting RTI mortality rates for the number of vehicle-kilometres travelled enables us to identify the high variability of this cause of death, and its relation with risk factors other than those inherent to human behaviour, such as the type of roads and the type of vehicles using them.

Published
2007
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4. Pre-hospital antibiotic treatment and mortality caused by invasive meningococcal disease, adjusting for indication bias

Author

Perea-Milla, Emilio, Olalla, Julián, Sánchez-Cantalejo, Emilio, Martos, Francisco, Matute-Cruz, Petra, Carmona-López, Guadalupe, Fornieles, Yolanda, Cayuela, Aurelio, García-Alegría, Javier, Jiménez-Puente, Alberto, Benitez-Parejo, Nicolás, Rebollo, Natividad, Rivas-Ruiz, Francisco, Ruiz-Canela, MaPaz, García-Martín, Francisco, Sánchez-Pérez, Ma José, Aguayo, Eduardo, Daponte, Antonio, Marquez, Soledad, Nieto, Ma Teresa, Romero-González, Julio, Díaz-Cabrera, Rocío, Lara, Antonio, The ANCA Group, [Perea-Milla,E, Olalla,J, García-Alegría J] Hospital Costa del Sol, Marbella, Spain. [Sánchez-Cantalejo,E, Carmona-López,G, Fornieles,Y] Escuela Andaluza de Salud Pública, Granada, Spain. [Martos,F] Facultad de Medicina, Universidad de Málaga, Málaga, Spain. [Matute-Cruz,P] Dirección General de Salud Pública, Tenerife, Spain. [Cayuela A] Hospital Virgen del Rocío, Seville, Spain. [Perea-Milla,E, Sánchez-Cantalejo,E, García-Alegría J] CIBER Epidemiología y Salud Pública (CIBERESP), Barcelona, Spain, and FIS (00/0049-01/02/03), Junta de Andalucía (247/00) and, partially, the IRYSS network (G03/202).

Subjects
Male, Pediatrics, Emergency Medical Services, Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Epidemiologic Study Characteristics as Topic::Epidemiologic Studies::Case-Control Studies::Retrospective Studies [Medical Subject Headings], Antibiotics, Administration, Oral, Estudios Retrospectivos, Oportunidad Relativa, Neisseria meningitidis, Logistic regression, Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Statistics as Topic::Confidence Intervals [Medical Subject Headings], Epidemiology, Odds Ratio, Medicine, Young adult, Child, Administración Oral, Organisms::Bacteria::Gram-Negative Bacteria::Gram-Negative Aerobic Bacteria::Gram-Negative Aerobic Rods and Cocci::Neisseriaceae::Neisseria::Neisseria meningitidis [Medical Subject Headings], lcsh:Public aspects of medicine, Analytical, Diagnostic and Therapeutic Techniques and Equipment::Therapeutics::Drug Therapy::Drug Administration Routes::Administration, Oral [Medical Subject Headings], Middle Aged, Anti-Bacterial Agents, Hospitalization, Antibacterianos, Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Statistics as Topic::Models, Statistical::Logistic Models [Medical Subject Headings], Intervalos de Confianza, Female, Research Article, Chemicals and Drugs::Chemical Actions and Uses::Pharmacologic Actions::Therapeutic Uses::Anti-Infective Agents::Anti-Bacterial Agents [Medical Subject Headings], Adult, medicine.medical_specialty, Adolescent, medicine.drug_class, Young Adult, Bias, Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Epidemiologic Study Characteristics as Topic::Epidemiologic Studies::Cohort Studies::Longitudinal Studies::Follow-Up Studies [Medical Subject Headings], Confidence Intervals, Humans, Modelos Logísticos, Aged, Retrospective Studies, business.industry, Health Care::Environment and Public Health::Public Health::Epidemiologic Factors::Bias (Epidemiology)::Selection Bias [Medical Subject Headings], Public Health, Environmental and Occupational Health, Retrospective cohort study, lcsh:RA1-1270, Odds ratio, Confidence interval, Meningococcal Infections, Logistic Models, Spain, Propensity score matching, business, Infecciones Meningocócicas, Health Care::Health Care Quality, Access, and Evaluation::Quality of Health Care::Health Care Evaluation Mechanisms::Statistics as Topic::Probability::Odds Ratio [Medical Subject Headings], Diseases::Bacterial Infections and Mycoses::Bacterial Infections::Gram-Negative Bacterial Infections::Neisseriaceae Infections::Meningococcal Infections [Medical Subject Headings], Follow-Up Studies
Abstract

Background Mortality from invasive meningococcal disease (IMD) has remained stable over the last thirty years and it is unclear whether pre-hospital antibiotherapy actually produces a decrease in this mortality. Our aim was to examine whether pre-hospital oral antibiotherapy reduces mortality from IMD, adjusting for indication bias. Methods A retrospective analysis was made of clinical reports of all patients (n = 848) diagnosed with IMD from 1995 to 2000 in Andalusia and the Canary Islands, Spain, and of the relationship between the use of pre-hospital oral antibiotherapy and mortality. Indication bias was controlled for by the propensity score technique, and a multivariate analysis was performed to determine the probability of each patient receiving antibiotics, according to the symptoms identified before admission. Data on in-hospital death, use of antibiotics and demographic variables were collected. A logistic regression analysis was then carried out, using death as the dependent variable, and pre-hospital antibiotic use, age, time from onset of symptoms to parenteral antibiotics and the propensity score as independent variables. Results Data were recorded on 848 patients, 49 (5.72%) of whom died. Of the total number of patients, 226 had received oral antibiotics before admission, mainly betalactams during the previous 48 hours. After adjusting the association between the use of antibiotics and death for age, time between onset of symptoms and in-hospital antibiotic treatment, pre-hospital oral antibiotherapy remained a significant protective factor (Odds Ratio for death 0.37, 95% confidence interval 0.15–0.93). Conclusion Pre-hospital oral antibiotherapy appears to reduce IMD mortality.

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