1. A nationwide cross-sectional review of in-hospital hepatitis B virus testing and disease burden estimation in Ghana, 2016 - 2021
- Author
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Yvonne Ayerki Nartey, Rafiq Okine, Atsu Seake-Kwawu, Georgia Ghartey, Yaw Karikari Asamoah, Kafui Senya, Amoako Duah, Alex Owusu-Ofori, James Amugsi, Damasus Suglo, Sally Afua Bampoh, Lindsey Hiebert, Henry Njuguna, John W. Ward, Amelie Plymoth, Lewis Rowland Roberts, Ansumana Sandy Bockarie, Yaw Asante Awuku, and Dorcas Obiri-Yeboah
- Subjects
Hepatitis B ,Testing ,Seroprevalence ,Ghana ,Sub-Saharan Africa ,Viral hepatitis elimination ,Public aspects of medicine ,RA1-1270 - Abstract
Abstract Background and aims Data are needed to inform hepatitis B virus (HBV) testing and treatment policies in Ghana to make progress towards achieving the 2030 WHO elimination targets. This study investigated testing patterns for HBV and described the age, sex, and region-specific prevalence of HBV infection in Ghana using hospital data. Methods A nationwide multi-centre cross-sectional study was performed where hospital-based registers were reviewed. These included review of 139,966 laboratory, 169,048 blood bank, and 83,920 delivery register entries from 22 healthcare institutions in Ghana. Frequencies and proportions, and crude and pooled estimates reported. Chi squared test was used for tests of independence. Logistic regression was used to identify factors associated with a positive test result. Results The crude HBsAg seroprevalence was 8.48% (95%CI 8.25–8.57%) with pooled estimate of 11.40% (95%CI 10.44–12.35). HBsAg seroprevalence among children under 5 years was 1.87% (95%CI 1.07-3.27) and highest age-specific seroprevalence was in those 40-49 years. The highest region-specific seroprevalences was in the Savannah (22.7%). Predictors of a positive HBsAg RDT test included female sex (OR 0.81 95% CI 0.74–0.88), and age (OR 1.005 95%CI 1.002–1.007). The proportion of parturient women receiving HBsAg testing increased between 2017 (87.2%) and 2020 (94.3%) (p
- Published
- 2022
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