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Your search keyword '"Jens Schlossmann"' showing total 3 results
Start Over Author "Jens Schlossmann" Journal bmc pharmacology & toxicology
3 results on '"Jens Schlossmann"'

2. Suppression of kidney fibrosis by cGMP-dependent protein kinase I

Author

Andrea Schramm, Franz Hofmann, Jens Schlossmann, Elisabeth Schinner, and Frieder Kees

Subjects
Pharmacology, business.industry, Kidney fibrosis, Pharmacology toxicology, Poster Presentation, Medicine, Pharmacology (medical), business, CGMP-Dependent Protein Kinase I
Published
2013

3. Identification of cCMP binding and activated proteins

Author

Stefanie Wolfertstetter, Franz Hofmann, Elisabeth Schinner, and Jens Schlossmann

Subjects
Pharmacology, chemistry.chemical_classification, Purine, Vascular smooth muscle, CCMP, Cytidine, Bioinformatics, chemistry.chemical_compound, Cyclic nucleotide, chemistry, Biochemistry, Second messenger system, Poster Presentation, Pharmacology (medical), Nucleotide, Protein kinase A
Abstract

Background cAMP and cGMP are well established second messengers and essential for numerous of (patho)physiological processes. These purine cyclic nucleotides activate PKA and PKG, respectively. So far, there was no evidence of further cyclic nucleotides acting as second messengers. Meanwhile the existence of cCMP was described [1]. Formation of the cyclic pyrimidine nucleotide cyclic cytidine 3’,5’-monophosphate (cCMP) by cytidylyl cyclases is debated. cCMP induces relaxation of vascular smooth muscle via cGKI [2]. Furthermore, it was postulated that cCMP is relevant for cell growth [3] and blood cell function [4]. However, functions regulated by cCMP are mostly unknown.

Published
2013

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