1. 25-hydroxyvitamin D Levels and chronic kidney disease in the AusDiab (Australian Diabetes, Obesity and Lifestyle) study
- Author
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Damasiewicz Matthew J, Magliano Dianna J, Daly Robin M, Gagnon Claudia, Lu Zhong X, Ebeling Peter R, Chadban Steven J, Atkins Robert C, Kerr Peter G, Shaw Jonathan E, and Polkinghorne Kevan R
- Subjects
Albuminuria ,Chronic kidney disease ,Glomerular filtration rate ,and Vitamin D ,Diseases of the genitourinary system. Urology ,RC870-923 - Abstract
Abstract Background Low 25-hydroxy vitamin D (25(OH)D) levels have been associated with an increased risk of albuminuria, however an association with glomerular filtration rate (GFR) is not clear. We explored the relationship between 25(OH)D levels and prevalent chronic kidney disease (CKD), albuminuria and impaired GFR, in a national, population-based cohort of Australian adults (AusDiab Study). Methods 10,732 adults ≥25 years of age participating in the baseline survey of the AusDiab study (1999–2000) were included. The GFR was estimated using an enzymatic creatinine assay and the CKD-EPI equation, with CKD defined as eGFR 2. Albuminuria was defined as a spot urine albumin to creatinine ratio (ACR) of ≥2.5 mg/mmol for men and ≥3.5 for women. Serum 25(OH)D levels of Results 30.7% of the study population had a 25(OH)D level Conclusions Vitamin D deficiency is common in this population, and 25(OH)D levels of
- Published
- 2012
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