1. [Untitled]
- Author
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Riccardo Parigi, Marco R. Oggioni, Elisabetta Blasi, Damiana Chiavolini, Sergio Tripodi, Susanna Ricci, Gianni Pozzi, and Marcella Cintorino
- Subjects
Microbiology (medical) ,Serotype ,Spleen ,Biology ,medicine.disease ,medicine.disease_cause ,Microbiology ,Pathogenesis ,Immune system ,medicine.anatomical_structure ,Parasitology ,Bacteremia ,Immunology ,Streptococcus pneumoniae ,medicine ,Meningitis - Abstract
Background Streptococcus pneumoniae is the leading cause of bacterial meningitis. Pneumococcal meningitis is associated with the highest mortality among bacterial meningitis and it may also lead to neurological sequelae despite the use of antibiotic therapy. Experimental animal models of pneumococcal meningitis are important to study the pathogenesis of meningitis, the host immune response induced after infection, and the efficacy of novel drugs and vaccines.
- Published
- 2004