9 results on '"Dorronsoro, Miren"'
Search Results
2. Exposure to bacterial products lipopolysaccharide and flagellin and hepatocellular carcinoma: a nested case-control study
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Fedirko, Veronika, primary, Tran, Hao Quang, additional, Gewirtz, Andrew T., additional, Stepien, Magdalena, additional, Trichopoulou, Antonia, additional, Aleksandrova, Krasimira, additional, Olsen, Anja, additional, Tjønneland, Anne, additional, Overvad, Kim, additional, Carbonnel, Franck, additional, Boutron-Ruault, Marie-Christine, additional, Severi, Gianluca, additional, Kühn, Tilman, additional, Kaaks, Rudolf, additional, Boeing, Heiner, additional, Bamia, Christina, additional, Lagiou, Pagona, additional, Grioni, Sara, additional, Panico, Salvatore, additional, Palli, Domenico, additional, Tumino, Rosario, additional, Naccarati, Alessio, additional, Peeters, Petra H., additional, Bueno-de-Mesquita, H. B., additional, Weiderpass, Elisabete, additional, Castaño, José María Huerta, additional, Barricarte, Aurelio, additional, Sánchez, María-José, additional, Dorronsoro, Miren, additional, Quirós, J. Ramón, additional, Agudo, Antonio, additional, Sjöberg, Klas, additional, Ohlsson, Bodil, additional, Hemmingsson, Oskar, additional, Werner, Mårten, additional, Bradbury, Kathryn E., additional, Khaw, Kay-Tee, additional, Wareham, Nick, additional, Tsilidis, Konstantinos K., additional, Aune, Dagfinn, additional, Scalbert, Augustin, additional, Romieu, Isabelle, additional, Riboli, Elio, additional, and Jenab, Mazda, additional
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- 2017
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3. Osteoprotegerin and breast cancer risk by hormone receptor subtype: a nested case-control study in the EPIC cohort
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Fortner, Renée T., primary, Sarink, Danja, additional, Schock, Helena, additional, Johnson, Theron, additional, Tjønneland, Anne, additional, Olsen, Anja, additional, Overvad, Kim, additional, Affret, Aurélie, additional, His, Mathilde, additional, Boutron-Ruault, Marie-Christine, additional, Boeing, Heiner, additional, Trichopoulou, Antonia, additional, Naska, Androniki, additional, Orfanos, Philippos, additional, Palli, Domenico, additional, Sieri, Sabina, additional, Mattiello, Amalia, additional, Tumino, Rosario, additional, Ricceri, Fulvio, additional, Bueno-de-Mesquita, H. Bas, additional, Peeters, Petra H. M., additional, Van Gils, Carla H., additional, Weiderpass, Elisabete, additional, Lund, Eiliv, additional, Quirós, J. Ramón, additional, Agudo, Antonio, additional, Sánchez, Maria-José, additional, Chirlaque, María-Dolores, additional, Ardanaz, Eva, additional, Dorronsoro, Miren, additional, Key, Tim, additional, Khaw, Kay-Tee, additional, Rinaldi, Sabina, additional, Dossus, Laure, additional, Gunter, Marc, additional, Merritt, Melissa A., additional, Riboli, Elio, additional, and Kaaks, Rudolf, additional
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- 2017
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4. Reproductive factors and risk of mortality in the European Prospective Investigation into Cancer and Nutrition; a cohort study
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Merritt, Melissa A., primary, Riboli, Elio, additional, Murphy, Neil, additional, Kadi, Mai, additional, Tjønneland, Anne, additional, Olsen, Anja, additional, Overvad, Kim, additional, Dossus, Laure, additional, Dartois, Laureen, additional, Clavel-Chapelon, Françoise, additional, Fortner, Renée T., additional, Katzke, Verena A., additional, Boeing, Heiner, additional, Trichopoulou, Antonia, additional, Lagiou, Pagona, additional, Trichopoulos, Dimitrios, additional, Palli, Domenico, additional, Sieri, Sabina, additional, Tumino, Rosario, additional, Sacerdote, Carlotta, additional, Panico, Salvatore, additional, Bueno-de-Mesquita, H. Bas, additional, Peeters, Petra H., additional, Lund, Eiliv, additional, Nakamura, Aurelie, additional, Weiderpass, Elisabete, additional, Quirós, J. Ramón, additional, Agudo, Antonio, additional, Molina-Montes, Esther, additional, Larrañaga, Nerea, additional, Dorronsoro, Miren, additional, Cirera, Lluís, additional, Barricarte, Aurelio, additional, Olsson, Åsa, additional, Butt, Salma, additional, Idahl, Annika, additional, Lundin, Eva, additional, Wareham, Nicholas J., additional, Key, Timothy J., additional, Brennan, Paul, additional, Ferrari, Pietro, additional, Wark, Petra A., additional, Norat, Teresa, additional, Cross, Amanda J., additional, and Gunter, Marc J., additional
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- 2015
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5. Metabolomic profiles of hepatocellular carcinoma in a European prospective cohort
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Fages, Anne, primary, Duarte-Salles, Talita, additional, Stepien, Magdalena, additional, Ferrari, Pietro, additional, Fedirko, Veronika, additional, Pontoizeau, Clément, additional, Trichopoulou, Antonia, additional, Aleksandrova, Krasimira, additional, Tjønneland, Anne, additional, Olsen, Anja, additional, Clavel-Chapelon, Françoise, additional, Boutron-Ruault, Marie-Christine, additional, Severi, Gianluca, additional, Kaaks, Rudolf, additional, Kuhn, Tilman, additional, Floegel, Anna, additional, Boeing, Heiner, additional, Lagiou, Pagona, additional, Bamia, Christina, additional, Trichopoulos, Dimitrios, additional, Palli, Domenico, additional, Pala, Valeria, additional, Panico, Salvatore, additional, Tumino, Rosario, additional, Vineis, Paolo, additional, Bueno-de-Mesquita, H. Bas, additional, Peeters, Petra H., additional, Weiderpass, Elisabete, additional, Agudo, Antonio, additional, Molina-Montes, Esther, additional, Huerta, José María, additional, Ardanaz, Eva, additional, Dorronsoro, Miren, additional, Sjöberg, Klas, additional, Ohlsson, Bodil, additional, Khaw, Kay-Tee, additional, Wareham, Nick, additional, Travis, Ruth C., additional, Schmidt, Julie A., additional, Cross, Amanda, additional, Gunter, Marc, additional, Riboli, Elio, additional, Scalbert, Augustin, additional, Romieu, Isabelle, additional, Elena-Herrmann, Benedicte, additional, and Jenab, Mazda, additional
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- 2015
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6. Pre-diagnostic concordance with the WCRF/AICR guidelines and survival in European colorectal cancer patients: a cohort study
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Romaguera, Dora, primary, Ward, Heather, additional, Wark, Petra A, additional, Vergnaud, Anne-Claire, additional, Peeters, Petra H, additional, van Gils, Carla H, additional, Ferrari, Pietro, additional, Fedirko, Veronika, additional, Jenab, Mazda, additional, Boutron-Ruault, Marie-Christine, additional, Dossus, Laure, additional, Dartois, Laureen, additional, Hansen, Camilla Plambeck, additional, Dahm, Christina Catherine, additional, Buckland, Genevieve, additional, Sánchez, María José, additional, Dorronsoro, Miren, additional, Navarro, Carmen, additional, Barricarte, Aurelio, additional, Key, Timothy J, additional, Trichopoulou, Antonia, additional, Tsironis, Christos, additional, Lagiou, Pagona, additional, Masala, Giovanna, additional, Pala, Valeria, additional, Tumino, Rosario, additional, Vineis, Paolo, additional, Panico, Salvatore, additional, Bueno-de-Mesquita, H Bas, additional, Siersema, Peter D, additional, Ohlsson, Bodil, additional, Jirström, Karin, additional, Wennberg, Maria, additional, Nilsson, Lena M, additional, Weiderpass, Elisabete, additional, Kühn, Tilman, additional, Katzke, Verena, additional, Khaw, Kay-Tee, additional, Wareham, Nick J, additional, Tjønneland, Anne, additional, Boeing, Heiner, additional, Quirós, José R, additional, Gunter, Marc J, additional, Riboli, Elio, additional, and Norat, Teresa, additional
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- 2015
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7. Association between plasma phospholipid saturated fatty acids and metabolic markers of lipid, hepatic, inflammation and glycaemic pathways in eight European countries: a cross-sectional analysis in the EPIC-InterAct study.
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Ju-Sheng Zheng, Sharp, Stephen J., Fumiaki Imamura, Koulman, Albert, Schulze, Matthias B., Zheng Ye, Griffin, Jules, Guevara, Marcela, Huerta, José María, Kröger, Janine, Sluijs, Ivonne, Agudo, Antonio, Barricarte, Aurelio, Boeing, Heiner, Colorado-Yohar, Sandra, Dow, Courtney, Dorronsoro, Miren, Dinesen, Pia T., Fagherazzi, Guy, and Franks, Paul W.
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PHOSPHOLIPIDS ,SATURATED fatty acids ,INFLAMMATION ,BODY mass index ,LIPIDS ,BLOOD sugar ,COMPARATIVE studies ,FATTY acids ,FAT content of food ,HIGH density lipoproteins ,LONGITUDINAL method ,LOW density lipoproteins ,RESEARCH methodology ,MEDICAL cooperation ,RESEARCH ,RESEARCH funding ,TRIGLYCERIDES ,EVALUATION research ,CROSS-sectional method - Abstract
Background: Accumulating evidence suggests that individual circulating saturated fatty acids (SFAs) are heterogeneous in their associations with cardio-metabolic diseases, but evidence about associations of SFAs with metabolic markers of different pathogenic pathways is limited. We aimed to examine the associations between plasma phospholipid SFAs and the metabolic markers of lipid, hepatic, glycaemic and inflammation pathways.Methods: We measured nine individual plasma phospholipid SFAs and derived three SFA groups (odd-chain: C15:0 + C17:0, even-chain: C14:0 + C16:0 + C18:0, and very-long-chain: C20:0 + C22:0 + C23:0 + C24:0) in individuals from the subcohort of the European Prospective Investigation into Cancer and Nutrition (EPIC)-InterAct case-cohort study across eight European countries. Using linear regression in 15,919 subcohort members, adjusted for potential confounders and corrected for multiple testing, we examined cross-sectional associations of SFAs with 13 metabolic markers. Multiplicative interactions of the three SFA groups with pre-specified factors, including body mass index (BMI) and alcohol consumption, were tested.Results: Higher levels of odd-chain SFA group were associated with lower levels of major lipids (total cholesterol (TC), triglycerides, apolipoprotein A-1 (ApoA1), apolipoprotein B (ApoB)) and hepatic markers (alanine transaminase (ALT), aspartate transaminase (AST), gamma-glutamyl transferase (GGT)). Higher even-chain SFA group levels were associated with higher levels of low-density lipoprotein cholesterol (LDL-C), TC/high-density lipoprotein cholesterol (HDL-C) ratio, triglycerides, ApoB, ApoB/A1 ratio, ALT, AST, GGT and CRP, and lower levels of HDL-C and ApoA1. Very-long-chain SFA group levels showed inverse associations with triglycerides, ApoA1 and GGT, and positive associations with TC, LDL-C, TC/HDL-C, ApoB and ApoB/A1. Associations were generally stronger at higher levels of BMI or alcohol consumption.Conclusions: Subtypes of SFAs are associated in a differential way with metabolic markers of lipid metabolism, liver function and chronic inflammation, suggesting that odd-chain SFAs are associated with lower metabolic risk and even-chain SFAs with adverse metabolic risk, whereas mixed findings were obtained for very-long-chain SFAs. The clinical and biochemical implications of these findings may vary by adiposity and alcohol intake. [ABSTRACT FROM AUTHOR]- Published
- 2017
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8. Combined impact of healthy lifestyle factors on colorectal cancer: a large European cohort study
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Aleksandrova, Krasimira, primary, Pischon, Tobias, additional, Jenab, Mazda, additional, Bueno-de-Mesquita, H Bas, additional, Fedirko, Veronika, additional, Norat, Teresa, additional, Romaguera, Dora, additional, Knüppel, Sven, additional, Boutron-Ruault, Marie-Christine, additional, Dossus, Laure, additional, Dartois, Laureen, additional, Kaaks, Rudolf, additional, Li, Kuanrong, additional, Tjønneland, Anne, additional, Overvad, Kim, additional, Quirós, José Ramón, additional, Buckland, Genevieve, additional, Sánchez, María José, additional, Dorronsoro, Miren, additional, Chirlaque, Maria-Dolores, additional, Barricarte, Aurelio, additional, Khaw, Kay-Tee, additional, Wareham, Nicholas J, additional, Bradbury, Kathryn E, additional, Trichopoulou, Antonia, additional, Lagiou, Pagona, additional, Trichopoulos, Dimitrios, additional, Palli, Domenico, additional, Krogh, Vittorio, additional, Tumino, Rosario, additional, Naccarati, Alessio, additional, Panico, Salvatore, additional, Siersema, Peter D, additional, Peeters, Petra HM, additional, Ljuslinder, Ingrid, additional, Johansson, Ingegerd, additional, Ericson, Ulrika, additional, Ohlsson, Bodil, additional, Weiderpass, Elisabete, additional, Skeie, Guri, additional, Borch, Kristin Benjaminsen, additional, Rinaldi, Sabina, additional, Romieu, Isabelle, additional, Kong, Joyce, additional, Gunter, Marc J, additional, Ward, Heather A, additional, Riboli, Elio, additional, and Boeing, Heiner, additional
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- 2014
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9. Pre-diagnostic concordance with the WCRF/AICR guidelines and survival in European colorectal cancer patients: a cohort study
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Carla H. van Gils, E. Riboli, Christos Tsironis, Anne-Claire Vergnaud, H. Bas Bueno-de-Mesquita, Laureen Dartois, José Ramón Quirós, Veronika Fedirko, Pietro Ferrari, Teresa Norat, Pagona Lagiou, Christina C. Dahm, Giovanna Masala, Timothy J. Key, Mark J. Gunter, Maria Wennberg, Kay-Tee Khaw, Verena Katzke, Petra H.M. Peeters, Aurelio Barricarte, Heather Ward, Nicholas J. Wareham, Anne Tjønneland, Lena Maria Nilsson, Bodil Ohlsson, Valeria Pala, Laure Dossus, Antonia Trichopoulou, Tilman Kühn, Heiner Boeing, Elisabete Weiderpass, Petra A. Wark, M. Dorronsoro, Carmen Navarro, Camilla Plambeck Hansen, Genevieve Buckland, Salvatore Panico, Marie-Christine Boutron-Ruault, María José Sánchez, Paolo Vineis, Peter D. Siersema, Karin Jirström, Dora Romaguera, Rosario Tumino, Mazda Jenab, Romaguera, Dora, Ward, Heather, Wark, Petra A, Vergnaud, Anne Claire, Peeters, Petra H, van Gils, Carla H, Ferrari, Pietro, Fedirko, Veronika, Jenab, Mazda, Boutron Ruault, Marie Christine, Dossus, Laure, Dartois, Laureen, Hansen, Camilla Plambeck, Dahm, Christina Catherine, Buckland, Genevieve, Sánchez, María José, Dorronsoro, Miren, Navarro, Carmen, Barricarte, Aurelio, Key, Timothy J, Trichopoulou, Antonia, Tsironis, Christo, Lagiou, Pagona, Masala, Giovanna, Pala, Valeria, Tumino, Rosario, Vineis, Paolo, Panico, Salvatore, Bueno de Mesquita, H. Ba, Siersema, Peter D, Ohlsson, Bodil, Jirström, Karin, Wennberg, Maria, Nilsson, Lena M, Weiderpass, Elisabete, Kühn, Tilman, Katzke, Verena, Khaw, Kay Tee, Wareham, Nick J, Tjønneland, Anne, Boeing, Heiner, Quirós, José R, Gunter, Marc J, Riboli, Elio, Norat, Teresa, Department of Medical and Clinical Genetics, Medicum, BMC, BMC, Department of Epidemiology and Public Health, Imperial College London, Instituto de Investigación Sanitaria de Palma (IdISPa), Hospital Universitario Son Espases, CIBER Fisiopatología de la Obesidad y Nutrición ( (CIBEROBN)), Instituto de Salud Carlos III [Madrid] (ISC), Department of Primary Care and Public Health, Department of Epidemiology, University Medical Center [Utrecht]-Julius Center for Health Sciences and Primary Care, Nutrition and Metabolism Section, International Agency for Cancer Research (IACR), Emory University [Atlanta, GA]-Rollins School of Public Health-Winship Cancer Institute, Centre de recherche en épidémiologie et santé des populations (CESP), Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Université Paris-Sud - Paris 11 (UP11)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpital Paul Brousse-Institut National de la Santé et de la Recherche Médicale (INSERM), Section for Epidemiology, Aarhus University [Aarhus], Unit of Nutrition, Environment and Cancer, Catalan Institute of Oncology (ICO-IDIBELL)-Cancer Epidemiology Research Programme, Granada Cancer Registry, Andalusian School of Public Health [Granada], Consorcio de Investigación Biomédica en Red especializado en Epidemiología y Salud Pública (CIBERESP), Los Centros de Investigación Biomédica en Red (CIBER), Murcia Regional Health Council [Murcia], Department of Health and Social Sciences, Universidad de Murcia, Navarre Public Health Institute, Cancer Epidemiology Unit, University of Oxford, Hellenic Health Foundation, Bureau of Epidemiologic Research, Academy of Athens, Department of Hygiene, Epidemiology and Medical Statistics, Harvard School of Public Health, Molecular and Nutritional Epidemiology Unit, Cancer Research and Prevention Institute-ISPO, Epidemiology and Prevention Unit, Fondazione IRCCS Istituto Nazionale Tumori - National Cancer Institute [Milan], Cancer Registry and Histopathology Unit, Department of Oncology-Civile - M.P.Arezzo Hospital, Human Genetics Foundation (HuGeF), Università degli studi di Torino = University of Turin (UNITO), Dipartimento di Medicina Clinica e Chirurgia, University of Naples Federico II = Università degli studi di Napoli Federico II, Department of Social and Preventive Medicine, Faculty of Medicine, University of Malaya = Universiti Malaya [Kuala Lumpur, Malaisie] (UM), Department for Determinants of Chronic Diseases (DCD), National Institute for Public Health and the Environment [Bilthoven] (RIVM), Department of Gastroenterology and Hepatology, University Medical Center [Utrecht], Division of Internal Medicine, Skane University Hospital [Malmo], Lund University [Lund]-Lund University [Lund], Division of Oncology and Pathology, Lund University [Lund], Department of Public Health and Clinical Medicine, Nutritional Research, Umeå University, Arctic Research Centre, Department of Community Medicine, The Arctic University of Norway [Tromsø, Norway] (UiT), Department of Research, Cancer Registry of Norway, Department of Medical Epidemiology and Biostatistics (MEB), Karolinska Institutet [Stockholm], Genetic Epidemiology Group [Helsinki], Folkhälsan Research Center, Faculty of Medecine [Helsinki], Helsingin yliopisto = Helsingfors universitet = University of Helsinki-Helsingin yliopisto = Helsingfors universitet = University of Helsinki-Faculty of Medecine [Helsinki], Helsingin yliopisto = Helsingfors universitet = University of Helsinki-Helsingin yliopisto = Helsingfors universitet = University of Helsinki, Division of Cancer Epidemiology, German Cancer Research Center - Deutsches Krebsforschungszentrum [Heidelberg] (DKFZ), Clinical Gerontology Unit, University of Cambridge [UK] (CAM), MRC Epidemiology Unit, University of Cambridge [UK] (CAM)-Institute of Metabolic Science, Danish Cancer Society Research Center, German Institute of Human Nutrition (DIfE) Potsdam-Rehbrücke, Public Health Directorate, Khaw, Kay-Tee [0000-0002-8802-2903], Wareham, Nicholas [0000-0003-1422-2993], Apollo - University of Cambridge Repository, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Université Paris-Sud - Paris 11 (UP11)-Hôpital Paul Brousse-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Versailles Saint-Quentin-en-Yvelines (UVSQ), University of Oxford [Oxford], Università degli studi di Torino (UNITO), University of Naples Federico II, University of Malaya, The Arctic University of Norway, University of Helsinki-University of Helsinki-Faculty of Medecine [Helsinki], University of Helsinki-University of Helsinki, [Romaguera,D, Ward,H, Vergnaud,A, Peeters,PH, Vineis,P, Bueno-de-Mesquita,HB, Gunter, MJ, Riboli,E, Norat,T] Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK. [Romaguera,D] Instituto de Investigación Sanitaria de Palma (IdISPa), Hospital Universitario Son Espases, Palma de Mallorca, Spain. [Romaguera,D] CIBER Fisiopatología de la Obesidad y Nutrición (CIBEROBN), Instituto de Salud Carlos III, Madrid, Spain. [Wark,PA] Global eHealth Unit, Department of Primary Care and Public Health, School of Public Health, Imperial College London, London, UK. [Peeters,PH, Gils, CH] Department of Epidemiology, Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands. [Ferrari,P, Jenab,M] International Agency for Cancer Research (IARC), Lyon CEDEX, France. [Fedirko,V] Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, USA. [Fedirko,V] Winship Cancer Institute, Emory University, Atlanta, USA. [Boutron-Ruault,M, Dossus,L, Dartois,L] Inserm (Institut National de la Santé et de la Recherche Médicale), Centre for Research in Epidemiology and Population Health (CESP), Vaillant, Villejuif, Cedex, France. [Boutron-Ruault,M, Dartois,L] Univ Paris Sud, Villejuif, France. [Boutron-Ruault,M, Dartois,L] Gustave Roussy, Villejuif, France. [Hansen,CP, Dahm,CC] Section for Epidemiology, Department of Public Health, Aarhus University, Aarhus C, Denmark. [Buckland,G] Unit of Nutrition, Environment and Cancer, Cancer Epidemiology Research Programme, Catalan Institute of Oncology (ICO-IDIBELL), Barcelona, Spain. [Sánchez,MJ] Escuela Andaluza de Salud Pública, Instituto de Investigación Biosanitaria ibs. GRANADA, Hospitales Universitarios de Granada/Universidad de Granada, Granada, Spain. [Sánchez,MJ, Dorronsoro,M, Navarro,C, Barricarte,A] CIBER de Epidemiología y Salud Pública (CIBERESP), Instituto de Salud Carlos III, Madrid, Spain. [Dorronsoro,M] Public Health Direction and Biodonostia Basque Regional Health Department, San Sebastian, Spain. [Navarro,C] Department of Epidemiology, Murcia Regional Health Council, Murcia, Spain. Department of Health and Social Sciences, Universidad de Murcia, Campus Universitario de Espinardo, Murcia, Spain. [Barricarte,A] Navarre Public Health Institute, Pamplona, Spain. [Key,TJ] Cancer Epidemiology Unit, Nuffield Department of Population Health, University of Oxford, Oxford UK. [Trichopoulou,A, Tsironis,C] Hellenic Health Foundation, Athens, Greece . [Trichopoulou,A, Lagiou,P] Bureau of Epidemiologic Research, Academy of Athens, Athens, Greece. [Lagiou,P] Department of Hygiene, Epidemiology and Medical Statistics, University of Athens Medical School, Athens, Greece. [Lagiou,P] Department of Epidemiology, Harvard School of Public Health, Boston, USA. [Masala,G] Molecular and Nutritional Epidemiology Unit, Cancer Research and Prevention Institute – ISPO, Florence, Italy. [Pala,V] Epidemiology and Prevention Unit, Fondazione IRCCS, Istituto Nazionale dei Tumori, Milan, Italy. [Tumino,R] Cancer Registry and Histopathology Unit, 'Civic – M.P. Arezzo' Hospital, Ragusa, Italy. [Vineis,P] HuGeF Foundation, Turin, Italy. [Panico,S] Dipartimento di Medicina Clinica e Chirurgia, Federico II University, Naples, Italy. [Bueno-de-Mesquita,HB] Department for Determinants of Chronic Diseases (DCD), National Institute for Public Health and the Environment (RIVM), Bilthoven The Netherlands. [Bueno-de-Mesquita,HB, Siersema,PD] Department of Gastroenterology and Hepatology, University Medical Centre, Utrecht, The Netherlands. [Bueno-de-Mesquita,HB] Department of Social and Preventive Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia. [Ohlsson,B] Division of Internal Medicine, Department of Clinical Sciences, Skane University Hospital, Malmo, Lund University, Lund, Sweden. [Jirström,K] Department of Clinical Sciences, Division of Oncology and Pathology, Lund University, Lund, Sweden. [Wennberg,M] Public Health and Clinical Medicine, Nutritional Research, Umeå University, Umeå, Sweden. [Nilsson,LM] Arctic Research Centre, Umeå University, Umeå, Sweden. [Weiderpass,E] Department of Community Medicine, Faculty of Health Sciences, University of Tromsø, The Arctic University of Norway, ISM - Universitetet i Tromsø, Tromsø, Norway. Department of Research, Cancer Registry of Norway, Majorstuen Oslo, Norway. Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden. Department of Genetic Epidemiology, Folkhälsan Research Center, Folkhälsan Research Center, Biomedicum 1, University of Helsinki, Helsinki, Finland. [Kühn,T, Katzke,V] German Cancer Research Center (DKFZ), Division of Cancer Epidemiology Im Neuenheimer Feld 581, Heidelberg, Germany. [Khaw,K] University of Cambridge School of Clinical Medicine, Clinical Gerontology Unit Box 251, Addenbrooke’s Hospital, Cambridge, UK. [Wareham,NJ] MRC Epidemiology Unit, University of Cambridge, Addenbrooke’s Hospital, Cambridge, UK. [Tjønneland,A] Danish Cancer Society Research Center, Copenhagen, Denmark. [Boeing,H] Department of Epidemiology, German Institute of Human Nutrition Potsdam-Rehbruecke, Nuthetal, Germany. [Quirós,JR] Public Health Directorate, Oviedo Asturias, Spain., This study was funded by the World Cancer Research Fund (WCRF) International Regular Grant Programme (Grant number 2009/44). Dora Romaguera holds a Ramon y Cajal contract (Ministerio de Economía y Competitividad, Spain and European Regional Development Fund, RYC-2011-08796). In addition, EPIC investigators acknowledge funding from the following agencies: Europe Against Cancer Program of the European Commission (SANCO), German Cancer Aid, German Cancer Research Center (DKFZ), German Federal Ministry of Education and Research (BMBF), Danish Cancer Society, Catalan Institute of Oncology, Spain, Health Research Fund (FIS) of the Spanish Ministry of Health, Spanish Regional Governments of Andalucía, Asturias, Basque Country, Murcia (no. 6236) and Navarra, ISCIII RCESP exp. C03/09 and ISCIII RETICC RD06/0020/0091, Spain, Cancer Research UK, Medical Research Council, United Kingdom, The Hellenic Health Foundation, Greece, Italian Association for Research on Cancer (AIRC), Italian National Research Council, Fondazione-Istituto Banco Napoli, Italy, Dutch Ministry of Public Health, Welfare and Sports, Dutch Prevention Funds, LK Research Funds, Dutch ZON (Zorg Onderzoek Nederland), World Cancer Research Fund (WCRF), The Netherlands, Swedish Cancer Society, Swedish Scientific Council, Regional Government of Skåne, Sweden, Helga—Nordic Center of Excellence Programme in Nutrition and Health, French League against Cancer (LNCC), National Institute for Health and Medical Research (INSERM), France, Mutuelle Générale de l'Education Romaguera et al. BMC Medicine (2015) 13:107 Page 10 of 12 Nationale (MGEN), France, 3 M Co., France, Gustave Roussy Institute (IGR), France, and and General Councils of France. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.
- Subjects
Male ,physical activity ,0302 clinical medicine ,estudios prospectivos ,Prospective Studies ,estudios de cohortes ,mediana edad ,Aged, 80 and over ,anciano ,Psychiatry and Psychology::Behavior and Behavior Mechanisms::Behavior::Motor Activity [Medical Subject Headings] ,dieta ,Incidence ,Hazard ratio ,COLON-CANCER ,General Medicine ,adulto ,3. Good health ,Näringslära ,[SDV] Life Sciences [q-bio] ,030220 oncology & carcinogenesis ,estilo de vida ,Cohort ,Dieta ,Estilo de Vida ,RESEARCH FUND/AMERICAN INSTITUTE ,Cohort study ,Human ,medicine.medical_specialty ,Concordance ,European Continental Ancestry Group ,DIAGNOSIS ,incidencia ,White People ,03 medical and health sciences ,SDG 3 - Good Health and Well-being ,Càncer colorectal ,Neoplasias Colorrectales ,BREAST-CANCER ,Humans ,Life Style ,Aged ,Cancer prevention ,Proportional hazards model ,Physical activity ,Diseases::Neoplasms::Neoplasms by Site::Digestive System Neoplasms::Gastrointestinal Neoplasms::Intestinal Neoplasms::Colorectal Neoplasms [Medical Subject Headings] ,Psychiatry and Psychology::Behavior and Behavior Mechanisms::Psychology, Social::Life Style [Medical Subject Headings] ,weight ,LIFE-STYLE FACTORS ,Colorectal cancer ,REPRODUCTIVE HISTORY ,Prospective Studie ,Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Epidemiologic Study Characteristics as Topic::Epidemiologic Studies::Cohort Studies [Medical Subject Headings] ,Cancer and Oncology ,Proportional Hazards Model ,grupo de ascendencia continental europea ,Estudios de Cohortes ,Gerontology ,cumplimiento del paciente ,Survival ,modelos de riesgos proporcionales ,VDP::Medisinske Fag: 700::Helsefag: 800::Epidemiologi medisinsk og odontologisk statistikk: 803 ,[SDV]Life Sciences [q-bio] ,humanos ,Colorectal Neoplasm ,Alcohol consumption ,Breast cancer ,Prospective study ,Named Groups::Persons::Survivors [Medical Subject Headings] ,Cohort Studies ,030212 general & internal medicine ,Prospective cohort study ,Non-U.S. Gov't ,2. Zero hunger ,Medicine(all) ,RISK ,Nutrition and Dietetics ,Healthy lifestyle ,Diet ,Weight ,Research Support, Non-U.S. Gov't ,Public Health, Global Health, Social Medicine and Epidemiology ,Middle Aged ,European Prospective Investigation into Cancer and Nutrition ,VDP::Medical disciplines: 700::Health sciences: 800::Epidemiology medical and dental statistics: 803 ,NUTRITION ,Female ,Colorectal Neoplasms ,Research Article ,Adult ,neoplasias colorrectales ,3122 Cancers ,RECREATIONAL PHYSICAL-ACTIVITY ,Other Research Radboud Institute for Molecular Life Sciences [Radboudumc 0] ,colorectal cancer ,Phenomena and Processes::Physiological Phenomena::Nutritional Physiological Phenomena::Diet [Medical Subject Headings] ,Research Support ,survival ,Sobrevivientes ,healthy lifestyle ,Internal medicine ,medicine ,Journal Article ,Proportional Hazards Models ,Actividad Motora ,business.industry ,Physical fitness ,BODY-MASS INDEX ,Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi ,Other Clinical Medicine ,3121 General medicine, internal medicine and other clinical medicine ,Patient Compliance ,Cohort Studie ,business ,diet ,Condició física - Abstract
Background: Cancer survivors are advised to follow lifestyle recommendations on diet, physical activity, and body fatness proposed by the World Cancer Research Fund/American Institute of Cancer Research (WCRF/AICR) for cancer prevention. Previous studies have demonstrated that higher concordance with these recommendations measured using an index score (the WCRF/AICR score) was associated with lower cancer incidence and mortality. The aim of this study was to evaluate the association between pre-diagnostic concordance with WCRF/AICR recommendations and mortality in colorectal cancer (CRC) patients. Methods: The association between the WCRF/AICR score (score range 0-6 in men and 0-7 in women; higher scores indicate greater concordance) assessed on average 6.4 years before diagnosis and CRC-specific (n = 872) and overall mortality (n = 1,113) was prospectively examined among 3,292 participants diagnosed with CRC in the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort (mean follow-up time after diagnosis 4.2 years). Multivariable Cox proportional hazard models were used to estimate hazard ratios (HRs) and 95% confidence intervals (CIs) for mortality. Results: The HRs (95% CIs) for CRC-specific mortality among participants in the second (score range in men/women: 2.25-2.75/3.25-3.75), third (3-3.75/4-4.75), and fourth (4-6/5-7) categories of the score were 0.87 (0.72-1.06), 0.74 (0.61-0.90), and 0.70 (0.56-0.89), respectively (P for trend, We would like to acknowledge the contribution of all participants in the study. This study was funded by the World Cancer Research Fund (WCRF) International Regular Grant Programme (Grant number 2009/44). Dora Romaguera holds a Ramon y Cajal contract (Ministerio de Economia y Competitividad, Spain and European Regional Development Fund; RYC-2011-08796). In addition, EPIC investigators acknowledge funding from the following agencies: Europe Against Cancer Program of the European Commission (SANCO); German Cancer Aid; German Cancer Research Center (DKFZ); German Federal Ministry of Education and Research (BMBF); Danish Cancer Society; Catalan Institute of Oncology, Spain; Health Research Fund (FIS) of the Spanish Ministry of Health; Spanish Regional Governments of Andalucia, Asturias, Basque Country, Murcia (no. 6236) and Navarra; ISCIII RCESP exp. C03/09 and ISCIII RETICC RD06/0020/0091, Spain; Cancer Research UK; Medical Research Council, United Kingdom; The Hellenic Health Foundation, Greece; Italian Association for Research on Cancer (AIRC); Italian National Research Council; Fondazione-Istituto Banco Napoli, Italy; Dutch Ministry of Public Health, Welfare and Sports, Dutch Prevention Funds, LK Research Funds, Dutch ZON (Zorg Onderzoek Nederland), World Cancer Research Fund (WCRF), The Netherlands; Swedish Cancer Society; Swedish Scientific Council; Regional Government of Skane, Sweden; Helga-Nordic Center of Excellence Programme in Nutrition and Health; French League against Cancer (LNCC); National Institute for Health and Medical Research (INSERM), France; Mutuelle Generale de l'Education Nationale (MGEN), France; 3 M Co., France; Gustave Roussy Institute (IGR), France; and General Councils of France.
- Published
- 2014
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