Search

Myocardial infarction (MI) is a life-threatening medical condition that necessitates both timely and precise diagnosis. The enhancement of automated method to detect MI diseases from Normal patients can play a crucial role in healthcare. This paper presents a novel approach that utilizes the Discrete Wavelet Transform (DWT) for the detection of myocardial signals. The DWT is employed to break down ECG signals into distinct frequency components and subsequently to selectively filter out noise by thresholding the high-frequency details, resulting in denoised ECG signals for myocardial signal detection. These denoised signals are fed into lightweight one-dimensional Convolutional Neural Networks (CNN) for binary classification into Myocardial Infarction (MI) and Normal categories. The paper explores three distinct approaches: utilizing all signals, incorporating under-sampling and up-sampling to address class imbalances, with both noised and denoised signals. Evaluation of the suggested model is done with the help of two publicly available datasets: PTB-XL, a large publicly available electrocardiography dataset and PTB Diagnostic ECG Database. Results obtained through 5-fold cross-validation on the trained model show that the model has achieved an accuracy of 96%, precision of 97% and F1 score of 95%. On cross-validation with the PTB-ECG dataset, this paper achieved an accuracy of 91.18%. [ABSTRACT FROM AUTHOR]

In recent years, the incidence of nodular thyroid diseases has been increasing annually. Ultrasonography has become a routine diagnostic tool for thyroid nodules due to its high real-time capabilities and low invasiveness. However, thyroid images obtained from current ultrasound tests often have low resolution and are plagued by significant noise interference. Regional differences in medical conditions and varying levels of physician experience can impact the accuracy and efficiency of diagnostic results. With the advancement of deep learning technology, deep learning models are used to identify whether a nodule in a thyroid ultrasound image is benign or malignant. This helps to close the gap between doctors' experience and equipment differences, improving the accuracy of the initial diagnosis of thyroid nodules. To cope with the problem that thyroid ultrasound images contain complex background and noise as well as poorly defined local features. in this paper, we first construct an improved ResNet50 classification model that uses a two-branch input and incorporates a global attention lightening module. This model is used to improve the accuracy of benign and malignant nodule classification in thyroid ultrasound images and to reduce the computational effort due to the two-branch structure.We constructed a U-net segmentation model incorporating our proposed ACR module, which uses hollow convolution with different dilation rates to capture multi-scale contextual information for feature extraction of nodules in thyroid ultrasound images and uses the results of the segmentation task as an auxiliary branch for the classification task to guide the classification model to focus on the lesion region more efficiently in the case of weak local features. The classification model is guided to focus on the lesion region more efficiently, and the classification and segmentation sub-networks are respectively improved specifically for this study, which is used to improve the accuracy of classifying the benign and malignant nature of the nodules in thyroid ultrasound images. The experimental results show that the four evaluation metrics of accuracy, precision, recall, and f1 of the improved model are 96.01%, 93.3%, 98.8%, and 96.0%, respectively. The improvements were 5.7%, 1.6%, 13.1%, and 7.4%, respectively, compared with the baseline classification model. [ABSTRACT FROM AUTHOR]

Objective: To conduct a systematic review of the computer vision applications that detect, diagnose, or analyse tuberculosis (TB) pathology or bacilli using digitised human lung tissue images either through automatic or semi-automatic methods. We categorised the computer vision platform into four technologies: image processing, object/pattern recognition, computer graphics, and deep learning. In this paper, the focus is on image processing and deep learning (DL) applications for either 2D or 3D digitised human lung tissue images. This review is useful for establishing a common practice in TB analysis using human lung tissue as well as identifying opportunities for further research in this space. The review brings attention to the state-of-art techniques for detecting TB, with emphasis on the challenges and limitations of the current techniques. The ultimate goal is to promote the development of more efficient and accurate algorithms for the detection or analysis of TB, and raise awareness about the importance of early detection. Design: We searched five databases and Google Scholar for articles published between January 2017 and December 2022 that focus on Mycobacterium tuberculosis detection, or tuberculosis pathology using digitised human lung tissue images. Details regarding design, image processing and computer-aided techniques, deep learning models, and datasets were collected and summarised. Discussions, analysis, and comparisons of state-of-the-art methods are provided to help guide future research. Further, a brief update on the relevant techniques and their performance is provided. Results: Several studies have been conducted to develop automated and AI-assisted methods for diagnosing Mtb and TB pathology from digitised human lung tissue images. Some studies presented a completely automated method of diagnosis, while other studies developed AI-assisted diagnostic methods. Low-level focus areas included the development of a novel μ CT scanner for soft tissue image contract, and use of multiresolution computed tomography to analyse the 3D structure of the human lung. High-level focus areas included the investigation the effects of aging on the number and size of small airways in the lungs using CT and whole lung high-resolution μ CT, and the 3D microanatomy characterisation of human tuberculosis lung using μ CT in conjunction with histology and immunohistochemistry. Additionally, a novel method for acquiring high-resolution 3D images of human lung structure and topology is also presented. Conclusion: The literature indicates that post 1950s, TB was predominantly studied using animal models even though no animal model reflects the full spectrum of human pulmonary TB disease and does not reproducibly transmit Mtb infection to other animals (Hunter, 2011). This explains why there are very few studies that used human lung tissue for detection or analysis of Mtb. Nonetheless, we found 10 studies that used human tissues (predominately lung) of which five studies proposed machine learning (ML) models for the detection of bacilli and the other five used CT on human lung tissue scanned ex-vivo. [ABSTRACT FROM AUTHOR]

Recent improvements in artificial intelligence and computer vision make it possible to automatically detect abnormalities in medical images. Skin lesions are one broad class of them. There are types of lesions that cause skin cancer, again with several types. Melanoma is one of the deadliest types of skin cancer. Its early diagnosis is at utmost importance. The treatments are greatly aided with artificial intelligence by the quick and precise diagnosis of these conditions. The identification and delineation of boundaries inside skin lesions have shown promise when using the basic image processing approaches for edge detection. Further enhancements regarding edge detections are possible. In this paper, the use of fractional differentiation for improved edge detection is explored on the application of skin lesion detection. A framework based on fractional differential filters for edge detection in skin lesion images is proposed that can improve automatic detection rate of malignant melanoma. The derived images are used to enhance the input images. Obtained images then undergo a classification process based on deep learning. A well-studied dataset of HAM10000 is used in the experiments. The system achieves 81.04% accuracy with EfficientNet model using the proposed fractional derivative based enhancements whereas accuracies are around 77.94% when using original images. In almost all the experiments, the enhanced images improved the accuracy. The results show that the proposed method improves the recognition performance. [ABSTRACT FROM AUTHOR]

Background: The quality of low-light endoscopic images involves applications in medical disciplines such as physiology and anatomy for the identification and judgement of tissue structures. Due to the use of point light sources and the constraints of narrow physiological structures, medical endoscopic images display uneven brightness, low contrast, and a lack of texture information, presenting diagnostic challenges for physicians. Methods: In this paper, a nonlinear brightness enhancement and denoising network based on Retinex theory is designed to improve the brightness and details of low-light endoscopic images. The nonlinear luminance enhancement module uses higher-order curvilinear functions to improve overall brightness; the dual-attention denoising module captures detailed features of anatomical structures; and the color loss function mitigates color distortion. Results: Experimental results on the Endo4IE dataset demonstrate that the proposed method outperforms existing state-of-the-art methods in terms of Peak Signal-to-Noise Ratio (PSNR), Structural Similarity (SSIM), and Learned Perceptual Image Patch Similarity (LPIPS). The PSNR is 27.2202, SSIM is 0.8342, and the LPIPS is 0.1492. It provides a method to enhance image quality in clinical diagnosis and treatment. Conclusions: It offers an efficient method to enhance images captured by endoscopes and offers valuable insights into intricate human physiological structures, which can effectively assist clinical diagnosis and treatment. [ABSTRACT FROM AUTHOR]

In the realm of disease prognosis and diagnosis, a plethora of medical images are utilized. These images are typically stored either within the local on-premises servers of healthcare providers or within cloud storage infrastructures. However, this conventional storage approach often incurs high infrastructure costs and results in sluggish information retrieval, ultimately leading to delays in diagnosis and consequential wastage of valuable time for patients. The methodology proposed in this paper offers a pioneering solution to expedite the diagnosis of medical conditions while simultaneously reducing infrastructure costs associated with data storage. Through this study, a high-speed biomedical image processing approach is designed to facilitate rapid prognosis and diagnosis. The proposed framework includes Deep learning QR code technique using an optimized database design aimed at alleviating the burden of intensive on-premises database requirements. The work includes medical dataset from Crawford Image and Data Archive and Duke CIVM for evaluating the proposed work suing different performance metrics, The work has also been compared from the previous research further enhancing the system's efficiency. By providing healthcare providers with high-speed access to medical records, this system enables swift retrieval of comprehensive patient details, thereby improving accuracy in diagnosis and supporting informed decision-making. [ABSTRACT FROM AUTHOR]

Problem: Breast cancer is a leading cause of death among women, and early detection is crucial for improving survival rates. The manual breast cancer diagnosis utilizes more time and is subjective. Also, the previous CAD models mostly depend on manmade visual details that are complex to generalize across ultrasound images utilizing distinct techniques. Distinct imaging tools have been utilized in previous works such as mammography and MRI. However, these imaging tools are costly and less portable than ultrasound imaging. Also, ultrasound imaging is a non-invasive method commonly used for breast cancer screening. Hence, the paper presents a novel deep learning model, BCDNet, for classifying breast tumors as benign or malignant using ultrasound images. Aim: The primary aim of the study is to design an effective breast cancer diagnosis model that can accurately classify tumors in their early stages, thus reducing mortality rates. The model aims to optimize the weight and parameters using the RPAOSM-ESO algorithm to enhance accuracy and minimize false negative rates. Methods: The BCDNet model utilizes transfer learning from a pre-trained VGG16 network for feature extraction and employs an AHDNAM classification approach, which includes ASPP, DTCN, 1DCNN, and an attention mechanism. The RPAOSM-ESO algorithm is used to fine-tune the weights and parameters. Results: The RPAOSM-ESO-BCDNet-based breast cancer diagnosis model provided 94.5 accuracy rates. This value is relatively higher than the previous models such as DTCN (88.2), 1DCNN (89.6), MobileNet (91.3), and ASPP-DTC-1DCNN-AM (93.8). Hence, it is guaranteed that the designed RPAOSM-ESO-BCDNet produces relatively accurate solutions for the classification than the previous models. Conclusion: The BCDNet model, with its sophisticated feature extraction and classification techniques optimized by the RPAOSM-ESO algorithm, shows promise in accurately classifying breast tumors using ultrasound images. The study suggests that the model could be a valuable tool in the early detection of breast cancer, potentially saving lives and reducing the burden on healthcare systems. [ABSTRACT FROM AUTHOR]

Ultrasound (US) imaging is an essential diagnostic technique in prenatal care, enabling enhanced surveillance of fetal growth and development. Fetal ultrasonography standard planes are crucial for evaluating fetal development parameters and detecting abnormalities. Real-time imaging, low cost, non-invasiveness, and accessibility make US imaging indispensable in clinical practice. However, acquiring fetal US planes with correct fetal anatomical features is a difficult and time-consuming task, even for experienced sonographers. Medical imaging using AI shows promise for addressing current challenges. In response to this challenge, a Deep Learning (DL)-based automated categorization method for maternal fetal US planes are introduced to enhance detection efficiency and diagnosis accuracy. This paper presents a hybrid optimization technique for feature selection and introduces a novel Radial Basis Function Neural Network (RBFNN) for reliable maternal fetal US plane classification. A large dataset of maternal–fetal screening US images was collected from publicly available sources and categorized into six groups: the four fetal anatomical planes, the mother's cervix, and an additional category. Feature extraction is performed using Gray-Level Co-occurrence Matrix (GLCM), and optimization methods such as Particle Swarm Optimization (PSO), Grey Wolf Optimization (GWO), and a hybrid Particle Swarm Optimization and Grey Wolf Optimization (PSOGWO) approach are utilized to select the most relevant features. The optimized features from each algorithm are then input into both conventional and proposed DL models. Experimental results indicate that the proposed approach surpasses conventional DL models in performance. Furthermore, the proposed model is evaluated against previously published models, showcasing its superior classification accuracy. In conclusion, our proposed approach provides a solid foundation for automating the classification of fetal US planes, leveraging optimization and DL techniques to enhance prenatal diagnosis and care. [ABSTRACT FROM AUTHOR]

Purpose: Automatic segmentation of brain tumors by deep learning algorithm is one of the research hotspots in the field of medical image segmentation. An improved FPN network for brain tumor segmentation is proposed to improve the segmentation effect of brain tumor. Materials and methods: Aiming at the problem that the traditional full convolutional neural network (FCN) has weak processing ability, which leads to the loss of details in tumor segmentation, this paper proposes a brain tumor image segmentation method based on the improved feature pyramid networks (FPN) convolutional neural network. In order to improve the segmentation effect of brain tumors, we improved the model, introduced the FPN structure into the U-Net structure, captured the context multi-scale information by using the different scale information in the U-Net model and the multi receptive field high-level features in the FPN convolutional neural network, and improved the adaptability of the model to different scale features. Results: Performance evaluation indicators show that the proposed improved FPN model has 99.1% accuracy, 92% DICE rating and 86% Jaccard index. The performance of the proposed method outperforms other segmentation models in each metric. In addition, the schematic diagram of the segmentation results shows that the segmentation results of our algorithm are closer to the ground truth, showing more brain tumour details, while the segmentation results of other algorithms are smoother. Conclusions: The experimental results show that this method can effectively segment brain tumor regions and has certain generalization, and the segmentation effect is better than other networks. It has positive significance for clinical diagnosis of brain tumors. [ABSTRACT FROM AUTHOR]

Background: Retinal vessel segmentation provides an important basis for determining the geometric characteristics of retinal vessels and the diagnosis of related diseases. The retinal vessels are mainly composed of coarse vessels and fine vessels, and the vessels have the problem of uneven distribution of coarse and fine vessels. At present, the common retinal blood vessel segmentation network based on deep learning can easily extract coarse vessels, but it ignores the more difficult to extract fine vessels. Methods: Scale-aware dense residual model, multi-output weighted loss and attention mechanism are proposed and incorporated into the U-shape network. The model is proposed to extract image features through residual module, and using a multi-scale feature aggregation method to extract the deep information of the network after the last encoder layer, and upsampling output at each decoder layer, compare the output results of each decoder layer with the ground truth separately to obtain multiple output losses, and the last layer of the decoder layers is used as the final prediction output. Result: The proposed network is tested on DRIVE and STARE. The evaluation indicators used in this paper are dice, accuracy, mIoU and recall rate. On the DRIVE dataset, the four indicators are respectively 80.40%, 96.67%, 82.14% and 88.10%; on the STARE dataset, the four indicators are respectively 83.41%, 97.39%, 84.38% and 88.84%. Conclusion: The experiment result proves that the network in this paper has better performance, can extract more continuous fine vessels, and reduces the problem of missing segmentation and false segmentation to a certain extent. [ABSTRACT FROM AUTHOR]

This paper presents a non-contact and unrestrained respiration monitoring system based on the optical triangulation technique. The proposed system consists of a red-green-blue (RGB) camera and a line laser installed to face the frontal thorax of a human body. The underlying idea of the work is that the camera and line laser are mounted in opposite directions, unlike other research. By applying the proposed image processing algorithm to the camera image, laser coordinates are extracted and converted to world coordinates using the optical triangulation method. These converted world coordinates represent the height of the thorax of a person. The respiratory rate is measured by analyzing changes of the thorax surface depth. To verify system performance, the camera and the line laser are installed on the head and foot sides of a bed, respectively, facing toward the center of the bed. Twenty healthy volunteers were enrolled and underwent measurement for 100s. Evaluation results show that the optical triangulation-based image processing method demonstrates non-inferior performance to a commercial patient monitoring system with a root-mean-squared error of 0.30rpm and a maximum error of 1rpm ( p > 0.05 ), which implies the proposed non-contact system can be a useful alternative to the conventional healthcare method. [ABSTRACT FROM AUTHOR]

Background: Automatic diagnosis and brain hemorrhage segmentation in Computed Tomography (CT) may be helpful in assisting the neurosurgeon in developing treatment plans that improve the patient's chances of survival. Because medical segmentation of images is important and performing operations manually is challenging, many automated algorithms have been developed for this purpose, primarily focusing on certain image modalities. Whenever a blood vessel bursts, a dangerous medical condition known as intracranial hemorrhage (ICH) occurs. For best results, quick action is required. That being said, identifying subdural (SDH) and epidural haemorrhages (EDH) is a difficult task in this field and calls for a new, more precise detection method. Methods: This work uses a head CT scan to detect cerebral bleeding and distinguish between two types of dural hemorrhages using deep learning techniques. This paper proposes a rich segmentation approach to segment both SDH and EDH by enhancing segmentation efficiency with a better feature extraction procedure. This method incorporates Spatial attention- based CSR (convolution-SE-residual) Unet, for rich segmentation and precise feature extraction. Results: According to the study's findings, the CSR based Spatial network performs better than the other models, exhibiting impressive metrics for all assessed parameters with a mean dice coefficient of 0.970 and mean IoU of 0.718, while EDH and SDH dice scores are 0.983 and 0.969 respectively. Conclusions: The CSR Spatial network experiment results show that it can perform well regarding dice coefficient. Furthermore, Spatial Unet based on CSR may effectively model the complicated in segmentations and rich feature extraction and improve the representation learning compared to alternative deep learning techniques, of illness and medical treatment, to enhance the meticulousness in predicting the fatality. [ABSTRACT FROM AUTHOR]

Early screening methods for the thyroid gland include palpation and imaging. Although palpation is relatively simple, its effectiveness in detecting early clinical signs of the thyroid gland may be limited, especially in children, due to the shorter thyroid growth time. Therefore, this constitutes a crucial foundational work. However, accurately determining the location and size of the thyroid gland in children is a challenging task. Accuracy depends on the experience of the ultrasound operator in current clinical practice, leading to subjective results. Even among experts, there is poor agreement on thyroid identification. In addition, the effective use of ultrasound machines also relies on the experience of the ultrasound operator in current clinical practice. In order to extract sufficient texture information from pediatric thyroid ultrasound images while reducing the computational complexity and number of parameters, this paper designs a novel U-Net-based network called DC-Contrast U-Net, which aims to achieve better segmentation performance with lower complexity in medical image segmentation. The results show that compared with other U-Net-related segmentation models, the proposed DC-Contrast U-Net model achieves higher segmentation accuracy while improving the inference speed, making it a promising candidate for deployment in medical edge devices in clinical applications in the future. [ABSTRACT FROM AUTHOR]

Background: Magnetic Resonance Imaging (MRI) is extensively utilized in clinical diagnostics and medical research, yet the imaging process is often compromised by noise interference. This noise arises from various sources, leading to a reduction in image quality and subsequently hindering the accurate interpretation of image details by clinicians. Traditional denoising methods typically assume that noise follows a Gaussian distribution, thereby neglecting the more complex noise types present in MRI images, such as Rician noise. As a result, denoising remains a challenging and practical task. Method: The main research work of this paper focuses on modifying mask information based on a global mask mapper. The mask mapper samples all blind spot pixels on the denoised image and maps them to the same channel. By incorporating perceptual loss, it utilizes all available information to improve performance while avoiding identity mapping. During the denoising process, the model may mistakenly remove some useful information as noise, resulting in a loss of detail in the denoised image. To address this issue, we train a generative adversarial network (GAN) with adaptive hybrid attention to restore the detailed information in the denoised MRI images. Result: The two-stage model NRAE shows an improvement of nearly 1.4 dB in PSNR and approximately 0.1 in SSIM on clinical datasets compared to other classic models. Specifically, compared to the baseline model, PSNR is increased by about 0.6 dB, and SSIM is only 0.015 lower. From a visual perspective, NRAE more effectively restores the details in the images, resulting in richer and clearer representation of image details. Conclusion: We have developed a deep learning-based two-stage model to address noise issues in medical MRI images. This method not only successfully reduces noise signals but also effectively restores anatomical details. The current results indicate that this is a promising approach. In future work, we plan to replace the current denoising network with more advanced models to further enhance performance. [ABSTRACT FROM AUTHOR]

Breast cancer prediction and diagnosis are critical for timely and effective treatment, significantly impacting patient outcomes. Machine learning algorithms have become powerful tools for improving the prediction and diagnosis of breast cancer. The Breast Cancer Prediction and Diagnosis Model (BCPM), which utilises machine learning techniques to improve the precision and efficiency of breast cancer diagnosis and prediction, is presented in this paper. BCPM collects comprehensive and high-quality data from diverse sources, including electronic medical records, clinical trials, and public datasets. Through rigorous pre-processing, the data is cleaned, inconsistencies are addressed, and missing values are handled. Feature scaling techniques are applied to normalize the data, ensuring fair comparison and equal importance among different features. Furthermore, feature-selection algorithms are utilized to identify the most relevant features that contribute to breast cancer projection and diagnosis, optimizing the model's efficiency. The BCPM employs numerous machine learning methods, such as logistic regression, random forests, decision trees, support vector machines, and neural networks, to generate accurate models. Area under the curve (AUC), sensitivity, specificity, and accuracy are only some of the metrics used to assess a model's performance once it has been trained on a subset of data. The BCPM holds promise in improving breast cancer prediction and diagnosis, aiding in personalized treatment planning, and ultimately taming patient results. By leveraging machine learning algorithms, the BCPM contributes to ongoing efforts in combating breast cancer and saving lives. [ABSTRACT FROM AUTHOR]

Background: CT and MRI modalities are important diagnostics tools for exploring the anatomical and tissue properties, respectively of the human beings. Several advancements like HRCT, FLAIR and Propeller have advantages in diagnosing the diseases very accurately, but still have enough space for improvements due to the presence of inherent and instrument noises. In the case of CT and MRI, the quantum mottle and the Gaussian and Rayleigh noises, respectively are still present in their advanced modalities of imaging. This paper addresses the denoising problem with continuum topological derivative technique and proved its trustworthiness based on the comparative study with other traditional filtration methods such as spatial, adaptive, frequency and transformation techniques using measures like visual inspection and performance metrics. Methods: This research study focuses on identifying a novel method for denoising by testing different filters on HRCT (High-Resolution Computed Tomography) and MR (Magnetic Resonance) images. The images were acquired from the Image Art Radiological Scan Centre using the SOMATOM CT and SIGNA Explorer (operating at 1.5 Tesla) machines. To compare the performance of the proposed CTD (Continuum Topological Derivative) method, various filters were tested on both HRCT and MR images. The filters tested for comparison were Gaussian (2D convolution operator), Wiener (deconvolution operator), Laplacian and Laplacian diagonal (2nd order partial differential operator), Average, Minimum, and Median (ordinary spatial operators), PMAD (Anisotropic diffusion operator), Kuan (statistical operator), Frost (exponential convolution operator), and HAAR Wavelet (time–frequency operator). The purpose of the study was to evaluate the effectiveness of the CTD method in removing noise compared to the other filters. The performance metrics were analyzed to assess the diligence of noise removal achieved by the CTD method. The primary outcome of the study was the removal of quantum mottle noise in HRCT images, while the secondary outcome focused on removing Gaussian (foreground) and Rayleigh (background) noise in MR images. The study aimed to observe the dynamics of noise removal by examining the values of the performance metrics. In summary, this study aimed to assess the denoising ability of various filters in HRCT and MR images, with the CTD method being the proposed approach. The study evaluated the performance of each filter using specific metrics and compared the results to determine the effectiveness of the CTD method in removing noise from the images. Results: Based on the calculated performance metric values, it has been observed that the CTD method successfully removed quantum mottle noise in HRCT images and Gaussian as well as Rayleigh noise in MRI. This can be evidenced by the PSNR (Peak Signal-to-Noise Ratio) metric, which consistently exhibited values ranging from 50 to 65 for all the tested images. Additionally, the CTD method demonstrated remarkably low residual values, typically on the order of e−09, which is a distinctive characteristic across all the images. Furthermore, the performance metrics of the CTD method consistently outperformed those of the other tested methods. Consequently, the results of this study have significant implications for the quality, structural similarity, and contrast of HRCT and MR images, enabling clinicians to obtain finer details for diagnostic purposes. Conclusion: Continuum topological derivative algorithm is found to be constructive in removing prominent noises in both CT and MRI images and can serve as a potential tool for recognition of anatomical details in case of diseased and normal ones. The results obtained from this research work are highly inspiring and offer great promise in obtaining accurate diagnostic information for critical cases such as Thoracic Cavity Carina, Brain SPI Globe Lens 4th Ventricle, Brain-Middle Cerebral Artery, Brain-Middle Cerebral Artery and neoplastic lesions. These findings lay the foundation for implementing the proposed CTD technique in routine clinical diagnosis. [ABSTRACT FROM AUTHOR]

Background: Cancer pathology shows disease development and associated molecular features. It provides extensive phenotypic information that is cancer-predictive and has potential implications for planning treatment. Based on the exceptional performance of computational approaches in the field of digital pathogenic, the use of rich phenotypic information in digital pathology images has enabled us to identify low-level gliomas (LGG) from high-grade gliomas (HGG). Because the differences between the textures are so slight, utilizing just one feature or a small number of features produces poor categorization results. Methods: In this work, multiple feature extraction methods that can extract distinct features from the texture of histopathology image data are used to compare the classification outcomes. The successful feature extraction algorithms GLCM, LBP, multi-LBGLCM, GLRLM, color moment features, and RSHD have been chosen in this paper. LBP and GLCM algorithms are combined to create LBGLCM. The LBGLCM feature extraction approach is extended in this study to multiple scales using an image pyramid, which is defined by sampling the image both in space and scale. The preprocessing stage is first used to enhance the contrast of the images and remove noise and illumination effects. The feature extraction stage is then carried out to extract several important features (texture and color) from histopathology images. Third, the feature fusion and reduction step is put into practice to decrease the number of features that are processed, reducing the computation time of the suggested system. The classification stage is created at the end to categorize various brain cancer grades. We performed our analysis on the 821 whole-slide pathology images from glioma patients in the Cancer Genome Atlas (TCGA) dataset. Two types of brain cancer are included in the dataset: GBM and LGG (grades II and III). 506 GBM images and 315 LGG images are included in our analysis, guaranteeing representation of various tumor grades and histopathological features. Results: The fusion of textural and color characteristics was validated in the glioma patients using the 10-fold cross-validation technique with an accuracy equals to 95.8%, sensitivity equals to 96.4%, DSC equals to 96.7%, and specificity equals to 97.1%. The combination of the color and texture characteristics produced significantly better accuracy, which supported their synergistic significance in the predictive model. The result indicates that the textural characteristics can be an objective, accurate, and comprehensive glioma prediction when paired with conventional imagery. Conclusion: The results outperform current approaches for identifying LGG from HGG and provide competitive performance in classifying four categories of glioma in the literature. The proposed model can help stratify patients in clinical studies, choose patients for targeted therapy, and customize specific treatment schedules. [ABSTRACT FROM AUTHOR]

Medical imaging stands as a critical component in diagnosing various diseases, where traditional methods often rely on manual interpretation and conventional machine learning techniques. These approaches, while effective, come with inherent limitations such as subjectivity in interpretation and constraints in handling complex image features. This research paper proposes an integrated deep learning approach utilizing pre-trained models—VGG16, ResNet50, and InceptionV3—combined within a unified framework to improve diagnostic accuracy in medical imaging. The method focuses on lung cancer detection using images resized and converted to a uniform format to optimize performance and ensure consistency across datasets. Our proposed model leverages the strengths of each pre-trained network, achieving a high degree of feature extraction and robustness by freezing the early convolutional layers and fine-tuning the deeper layers. Additionally, techniques like SMOTE and Gaussian Blur are applied to address class imbalance, enhancing model training on underrepresented classes. The model's performance was validated on the IQ-OTH/NCCD lung cancer dataset, which was collected from the Iraq-Oncology Teaching Hospital/National Center for Cancer Diseases over a period of three months in fall 2019. The proposed model achieved an accuracy of 98.18%, with precision and recall rates notably high across all classes. This improvement highlights the potential of integrated deep learning systems in medical diagnostics, providing a more accurate, reliable, and efficient means of disease detection. [ABSTRACT FROM AUTHOR]

Polypharmacy involves an individual using many medications at the same time and is a frequent healthcare technique used to treat complex medical disorders. Nevertheless, it also presents substantial risks of negative medication responses and interactions. Identifying and addressing adverse effects caused by polypharmacy is crucial to ensure patient safety and improve healthcare results. This paper introduces a new method using Graph Convolutional Networks (GCN) to identify polypharmacy side effects. Our strategy involves developing a medicine interaction graph in which edges signify drug-drug intuitive predicated on pharmacological properties and hubs symbolize drugs. GCN is a well-suited profound learning procedure for graph-based representations of social information. It can be used to anticipate the probability of medicate unfavorable impacts and to memorize important representations of sedate intuitive. Tests were conducted on a huge dataset of patients' pharmaceutical records commented on with watched medicate unfavorable impacts in arrange to approve our strategy. Execution of the GCN show, which was prepared on a subset of this dataset, was evaluated through a disarray framework. The perplexity network shows the precision with which the show categories occasions. Our discoveries demonstrate empowering advance within the recognizable proof of antagonistic responses related with polypharmaceuticals. For cardiovascular system target drugs, GCN technique achieved an accuracy of 94.12%, precision of 86.56%, F1-Score of 88.56%, AUC of 89.74% and recall of 87.92%. For respiratory system target drugs, GCN technique achieved an accuracy of 93.38%, precision of 85.64%, F1-Score of 89.79%, AUC of 91.85% and recall of 86.35%. And for nervous system target drugs, GCN technique achieved an accuracy of 95.27%, precision of 88.36%, F1-Score of 86.49%, AUC of 88.83% and recall of 84.73%. This research provides a significant contribution to pharmacovigilance by proposing a data-driven method to detect and reduce polypharmacy side effects, thereby increasing patient safety and healthcare decision-making. [ABSTRACT FROM AUTHOR]

Background: Information complementarity can be achieved by fusing MR and CT images, and fusion images have abundant soft tissue and bone information, facilitating accurate auxiliary diagnosis and tumor target delineation. Purpose: The purpose of this study was to construct high-quality fusion images based on the MR and CT images of intracranial tumors by using the Residual-Residual Network (Res2Net) method. Methods: This paper proposes an MR and CT image fusion method based on Res2Net. The method comprises three components: feature extractor, fusion layer, and reconstructor. The feature extractor utilizes the Res2Net framework to extract multiscale features from source images. The fusion layer incorporates a fusion strategy based on spatial mean attention, adaptively adjusting fusion weights for feature maps at each position to preserve fine details from the source images. Finally, fused features are input into the feature reconstructor to reconstruct a fused image. Results: Qualitative results indicate that the proposed fusion method exhibits clear boundary contours and accurate localization of tumor regions. Quantitative results show that the method achieves average gradient, spatial frequency, entropy, and visual information fidelity for fusion metrics of 4.6771, 13.2055, 1.8663, and 0.5176, respectively. Comprehensive experimental results demonstrate that the proposed method preserves more texture details and structural information in fused images than advanced fusion algorithms, reducing spectral artifacts and information loss and performing better in terms of visual quality and objective metrics. Conclusion: The proposed method effectively combines MR and CT image information, allowing the precise localization of tumor region boundaries, assisting clinicians in clinical diagnosis. [ABSTRACT FROM AUTHOR]

The quick proliferation of pandemic diseases has been imposing many concerns on the international health infrastructure. To combat pandemic diseases in smart cities, Artificial Intelligence of Things (AIoT) technology, based on the integration of artificial intelligence (AI) with the Internet of Things (IoT), is commonly used to promote efficient control and diagnosis during the outbreak, thereby minimizing possible losses. However, the presence of multi-source institutional data remains one of the major challenges hindering the practical usage of AIoT solutions for pandemic disease diagnosis. This paper presents a novel framework that utilizes multi-site data fusion to boost the accurateness of pandemic disease diagnosis. In particular, we focus on a case study of COVID-19 lesion segmentation, a crucial task for understanding disease progression and optimizing treatment strategies. In this study, we propose a novel multi-decoder segmentation network for efficient segmentation of infections from cross-domain CT scans in smart cities. The multi-decoder segmentation network leverages data from heterogeneous domains and utilizes strong learning representations to accurately segment infections. Performance evaluation of the multi-decoder segmentation network was conducted on three publicly accessible datasets, demonstrating robust results with an average dice score of 89.9% and an average surface dice of 86.87%. To address scalability and latency issues associated with centralized cloud systems, fog computing (FC) emerges as a viable solution. FC brings resources closer to the operator, offering low latency and energy-efficient data management and processing. In this context, we propose a unique FC technique called PANDFOG to deploy the multi-decoder segmentation network on edge nodes for practical and clinical applications of automated COVID-19 pneumonia analysis. The results of this study highlight the efficacy of the multi-decoder segmentation network in accurately segmenting infections from cross-domain CT scans. Moreover, the proposed PANDFOG system demonstrates the practical deployment of the multi-decoder segmentation network on edge nodes, providing real-time access to COVID-19 segmentation findings for improved patient monitoring and clinical decision-making. [ABSTRACT FROM AUTHOR]

In response to the low real-time performance and accuracy of traditional sports injury monitoring, this article conducts research on a real-time injury monitoring system using the SVM model as an example. Video detection is performed to capture human movements, followed by human joint detection. Polynomial fitting analysis is used to extract joint motion patterns, and the average of training data is calculated as a reference point. The raw data is then normalized to adjust position and direction, and dimensionality reduction is achieved through singular value decomposition to enhance processing efficiency and model training speed. A support vector machine classifier is used to classify and identify the processed data. The experimental section monitors sports injuries and investigates the accuracy of the system's monitoring. Compared to mainstream models such as Random Forest and Naive Bayes, the SVM utilized demonstrates good performance in accuracy, sensitivity, and specificity, reaching 94.2%, 92.5%, and 96.0% respectively. [ABSTRACT FROM AUTHOR]

Cerebral infarction is a common neurological disease with high rates of morbidity, mortality, and recurrence, posing a great threat to human life and health. Cerebral infarction is the second leading cause of death in the world and the leading cause of long-term disability in humans. The results of the third national retrospective sampling survey on causes of death in 2008 showed that cerebral infarction has become the leading cause of death in China and its mortality rate is 4–5 times that of European and American countries. Therefore, this article proposed a study on the predictive value of Cmmi-MHR combined with thromboelastography parameters that was performed for acute cerebral infarction. This paper mainly proposed a high frame rate imaging technology and analyzed its algorithm. In this article, in the experimental part, an in-depth analysis of the predictive value of the Monocyte-to-high-density lipoprotein cholesterol ratio (MHR) combined with thromboelastography parameters was performed for acute cerebral infarction. The final experimental results showed that HDL (OR = 1.695%, P-trend = 0.049) had a probability of death within 90 days of hospitalization (OR = 0.81, 95% CI = 1.06–3.11, P-trend = 0.523). There were no significant differences in mortality rate after 90 days. Regardless of adjusting for confounders such as age, gender, and NIHSS score, there was no significant difference in the risk of MHR or monocyte count within 90 days of hospitalization. The conclusion indicates that the combination of Cmmi-MHR and thromboelastography parameters provides a new perspective and method for the diagnosis and treatment of cerebral infarction, and provides important support for personalized treatment and management of cerebral infarction. [ABSTRACT FROM AUTHOR]

Categorizing Artificial Intelligence of Medical Things (AIoMT) devices within the realm of standard Internet of Things (IoT) and Internet of Medical Things (IoMT) devices, particularly at the server and computational layers, poses a formidable challenge. In this paper, we present a novel methodology for categorizing AIoMT devices through the application of decentralized processing, referred to as "Federated Learning" (FL). Our approach involves deploying a system on standard IoT devices and labeled IoMT devices for training purposes and attribute extraction. Through this process, we extract and map the interconnected attributes from a global federated cum aggression server. The aim of this terminology is to extract interdependent devices via federated learning, ensuring data privacy and adherence to operational policies. Consequently, a global training dataset repository is coordinated to establish a centralized indexing and synchronization knowledge repository. The categorization process employs generic labels for devices transmitting medical data through regular communication channels. We evaluate our proposed methodology across a variety of IoT, IoMT, and AIoMT devices, demonstrating effective classification and labeling. Our technique yields a reliable categorization index for facilitating efficient access and optimization of medical devices within global servers. [ABSTRACT FROM AUTHOR]

Background: Accurate grading of semantic characteristics is helpful for radiologists to determine the probabilities of the likelihood of malignancy of a pulmonary nodule. Nevertheless, because of the complex and varied properties of pulmonary nodules, assessing semantic characteristics (SC) is a difficult task. Method: In this paper, we first analyze a set of important semantic characteristics of pulmonary nodules and extract the important SCs relating to pulmonary nodule malignancy by Pearson's correlation approach. Then, we propose three automatic SC grading models based on deep belief network (DBN) and a multi-branch convolutional neural network (CNN) classifier, MBCNN. The first DBN model takes grayscale and binary nodule images as the input, and the second DBN model takes grayscale nodule images and 72 features extracted from pulmonary nodules as the input. Results: Experimental results indicate that our algorithms can achieve satisfying results on semantic characteristic grading. Especially, the MBCNN can obtain higher semantic characteristic grading results with an average accuracy of 89.37%. Conclusions: Quantitative and automatic grading of semantic characteristics proposed in this paper can assist radiologists effectively assess the likelihood of pulmonary nodules being malignant and further promote the early expectant treatment of malignant nodules. [ABSTRACT FROM AUTHOR]

Fundus ultrasound image classification is a critical issue in the medical field. Vitreous opacity (VO) and posterior vitreous detachment (PVD) are two common eye diseases, Now, the diagnosis of these two diseases mainly relies on manual identification by doctors. This method has the disadvantages of time-consuming and manual investment, so it is very meaningful to use computer technology to assist doctors in diagnosis. This paper is the first to apply the deep learning model to VO and PVD classification tasks. Convolutional neural network (CNN) is widely used in image classification. Traditional CNN requires a large amount of training data to prevent overfitting, and it is difficult to learn the differences between two kinds of images well. In this paper, we propose an end-to-end siamese convolutional neural network with multi-attention (SVK_MA) for automatic classification of VO and PVD fundus ultrasound images. SVK_MA is a siamese-structure network in which each branch is mainly composed of pretrained VGG16 embedded with multiple attention models. Each image first is normalized, then is sent to SVK_MA to extract features from the normalized images, and finally gets the classification result. Our approach has been validated on the dataset provided by the cooperative hospital. The experimental results show that our approach achieves the accuracy of 0.940, precision of 0.941, recall of 0.940, F1 of 0.939 which are respectively increased by 2.5%, 1.9%, 3.4% and 2.5% compared with the second highest model. [ABSTRACT FROM AUTHOR]

Background: Ultrasonic echocardiography is commonly used for monitoring myocardial dysfunction. However, it has limitations such as poor quality of echocardiography images and subjective judgment of doctors. Methods: In this paper, a calculation model based on optical flow tracking of echocardiogram is proposed for the quantitative estimation motion of the segmental wall. To improve the accuracy of optical flow estimation, a method based on confidence-optimized multiresolution(COM) optical flow model is proposed to reduce the estimation errors caused by the large amplitude of myocardial motion and the presence of "shadows" and other image quality problems. In addition, motion vector decomposition and dynamic tracking of the ventricular region of interest are used to extract information regarding the myocardial segmental motion. The proposed method was validated using simulation images and 50 clinical cases (25 patients and 25 healthy volunteers) for myocardial motion analysis. Results: The results demonstrated that the proposed method could track the motion information of myocardial segments well and reduce the estimation errors of optical flow caused due to the use of low-quality echocardiogram images. Conclusions: The proposed method improves the accuracy of motion estimation for the cardiac ventricular wall. [ABSTRACT FROM AUTHOR]

Breast Cancer is a significant global health challenge, particularly affecting women with higher mortality compared with other cancer types. Timely detection of such cancer types is crucial, and recent research, employing deep learning techniques, shows promise in earlier detection. The research focuses on the early detection of such tumors using mammogram images with deep-learning models. The paper utilized four public databases where a similar amount of 986 mammograms each for three classes (normal, benign, malignant) are taken for evaluation. Herein, three deep CNN models such as VGG-11, Inception v3, and ResNet50 are employed as base classifiers. The research adopts an ensemble method where the proposed approach makes use of the modified Gompertz function for building a fuzzy ranking of the base classification models and their decision scores are integrated in an adaptive manner for constructing the final prediction of results. The classification results of the proposed fuzzy ensemble approach outperform transfer learning models and other ensemble approaches such as weighted average and Sugeno integral techniques. The proposed ResNet50 ensemble network using the modified Gompertz function-based fuzzy ranking approach provides a superior classification accuracy of 98.986%. [ABSTRACT FROM AUTHOR]

Objective: The paper aimed to improve the accuracy limitations of traditional two-dimensional ultrasound and surgical procedures in the diagnosis and management of congenital heart disease (chd), and to improve the diagnostic and therapeutic level of chd. Method: This article first collected patient data through real-time imaging and body surface probes, and then diagnosed 150 patients using three-dimensional echocardiography. In order to verify the effectiveness of the combination therapy, 60 confirmed patients were divided into a control group and an experimental group. The control group received conventional two-dimensional ultrasound and surgical treatment, while the experimental group received three-dimensional ultrasound and image guided surgical treatment. Result: In the second diagnosis, the diagnostic accuracy of type 1, type 2, and type 3 in the control group was 84.21%, 84.02%, and 83.38%, respectively. The diagnostic accuracy rates of type 1, type 2, and type 3 in the experimental group were 92.73%, 92.82%, and 92.83%, respectively. In the control group, 2 males and 1 female experienced heart failure after surgery. However, in the experimental group, 0 males and 0 females experienced heart failure after surgery. Conclusion: The combination of three-dimensional echocardiography and image guided surgery can improve diagnostic accuracy and surgical treatment effectiveness, thereby reducing risks and complications, and improving surgical success rate. [ABSTRACT FROM AUTHOR]

Pulmonary diseases are various pathological conditions that affect respiratory tissues and organs, making the exchange of gas challenging for animals inhaling and exhaling. It varies from gentle and self-limiting such as the common cold and catarrh, to life-threatening ones, such as viral pneumonia (VP), bacterial pneumonia (BP), and tuberculosis, as well as a severe acute respiratory syndrome, such as the coronavirus 2019 (COVID-19). The cost of diagnosis and treatment of pulmonary infections is on the high side, most especially in developing countries, and since radiography images (X-ray and computed tomography (CT) scan images) have proven beneficial in detecting various pulmonary infections, many machine learning (ML) models and image processing procedures have been utilized to identify these infections. The need for timely and accurate detection can be lifesaving, especially during a pandemic. This paper, therefore, suggested a deep convolutional neural network (DCNN) founded image detection model, optimized with image augmentation technique, to detect three (3) different pulmonary diseases (COVID-19, bacterial pneumonia, and viral pneumonia). The dataset containing four (4) different classes (healthy (10,325), COVID-19 (3,749), BP (883), and VP (1,478)) was utilized as training/testing data for the suggested model. The model's performance indicates high potential in detecting the three (3) classes of pulmonary diseases. The model recorded average detection accuracy of 94%, 95.4%, 99.4%, and 98.30%, and training/detection time of about 60/50 s. This result indicates the proficiency of the suggested approach when likened to the traditional texture descriptors technique of pulmonary disease recognition utilizing X-ray and CT scan images. This study introduces an innovative deep convolutional neural network model to enhance the detection of pulmonary diseases like COVID-19 and pneumonia using radiography. This model, notable for its accuracy and efficiency, promises significant advancements in medical diagnostics, particularly beneficial in developing countries due to its potential to surpass traditional diagnostic methods. [ABSTRACT FROM AUTHOR]

Background: Dynamic Contrast Enhanced Magnetic Resonance Imaging (DCE-MRI) plays an important role in the diagnosis and treatment of breast cancer. However, obtaining complete eight temporal images of DCE-MRI requires a long scanning time, which causes patients' discomfort in the scanning process. Therefore, to reduce the time, the multi temporal feature fusing neural network with Co-attention (MTFN) is proposed to generate the eighth temporal images of DCE-MRI, which enables the acquisition of DCE-MRI images without scanning. In order to reduce the time, multi-temporal feature fusion cooperative attention mechanism neural network (MTFN) is proposed to generate the eighth temporal images of DCE-MRI, which enables DCE-MRI image acquisition without scanning. Methods: In this paper, we propose multi temporal feature fusing neural network with Co-attention (MTFN) for DCE-MRI Synthesis, in which the Co-attention module can fully fuse the features of the first and third temporal image to obtain the hybrid features. The Co-attention explore long-range dependencies, not just relationships between pixels. Therefore, the hybrid features are more helpful to generate the eighth temporal images. Results: We conduct experiments on the private breast DCE-MRI dataset from hospitals and the multi modal Brain Tumor Segmentation Challenge2018 dataset (BraTs2018). Compared with existing methods, the experimental results of our method show the improvement and our method can generate more realistic images. In the meanwhile, we also use synthetic images to classify the molecular typing of breast cancer that the accuracy on the original eighth time-series images and the generated images are 89.53% and 92.46%, which have been improved by about 3%, and the classification results verify the practicability of the synthetic images. Conclusions: The results of subjective evaluation and objective image quality evaluation indicators show the effectiveness of our method, which can obtain comprehensive and useful information. The improvement of classification accuracy proves that the images generated by our method are practical. [ABSTRACT FROM AUTHOR]

Background: One challenge to train deep convolutional neural network (CNNs) models with whole slide images (WSIs) is providing the required large number of costly, manually annotated image regions. Strategies to alleviate the scarcity of annotated data include: using transfer learning, data augmentation and training the models with less expensive image-level annotations (weakly-supervised learning). However, it is not clear how to combine the use of transfer learning in a CNN model when different data sources are available for training or how to leverage from the combination of large amounts of weakly annotated images with a set of local region annotations. This paper aims to evaluate CNN training strategies based on transfer learning to leverage the combination of weak and strong annotations in heterogeneous data sources. The trade-off between classification performance and annotation effort is explored by evaluating a CNN that learns from strong labels (region annotations) and is later fine-tuned on a dataset with less expensive weak (image-level) labels. Results: As expected, the model performance on strongly annotated data steadily increases as the percentage of strong annotations that are used increases, reaching a performance comparable to pathologists ( κ = 0.691 ± 0.02 ). Nevertheless, the performance sharply decreases when applied for the WSI classification scenario with κ = 0.307 ± 0.133 . Moreover, it only provides a lower performance regardless of the number of annotations used. The model performance increases when fine-tuning the model for the task of Gleason scoring with the weak WSI labels κ = 0.528 ± 0.05 . Conclusion: Combining weak and strong supervision improves strong supervision in classification of Gleason patterns using tissue microarrays (TMA) and WSI regions. Our results contribute very good strategies for training CNN models combining few annotated data and heterogeneous data sources. The performance increases in the controlled TMA scenario with the number of annotations used to train the model. Nevertheless, the performance is hindered when the trained TMA model is applied directly to the more challenging WSI classification problem. This demonstrates that a good pre-trained model for prostate cancer TMA image classification may lead to the best downstream model if fine-tuned on the WSI target dataset. We have made available the source code repository for reproducing the experiments in the paper: https://github.com/ilmaro8/Digital_Pathology_Transfer_Learning [ABSTRACT FROM AUTHOR]

Background: Medical image segmentation is an important processing step in most of medical image analysis. Thus, high accuracy and robustness are required for them. The current deep neural network based medical segmentation methods have good effect on image with balanced foreground and background, but it will loss the characteristics of small targets on image with imbalanced foreground and background after multiple convolutions. Methods: In order to retain the features of small targets in the deep network, we proposed a new medical image segmentation model based on the U-Net with squeeze-and-excitation and attention modules which form a spiral closed path,callled as Spiral Squeeze-and-Excitation and Attention NET (SEA-NET) in this paper. The segmentation model used squeeze-and-extraction modules to adjust the channel information to enhance the useful information and used attention modules to adjust the spatial information of the feature map to highlight the target area for small target segmentation when up-sampling. The deep semantic information is integrated into the shallow feature map by the attention model. Therefore, the deep semantic information cannot be scattered by continuous up-sampling. We used cross entropy loss + Tversky loss function for fast convergence and well processing the imbalanced data sets. Our proposed SEA-NET was tested on the brain MRI dataset LPBA40 and peripheral blood smear images. Conclusions: On brain MRI data, the average value of the Dice coefficient we obtained reached 98.1 % . On the peripheral blood smear dataset, our proposed model has a good segmentation effect on adhesion cells. Results: The experimental results proved that the proposed SEA-Net performed better than U-Net, U-Net++, etc. in medical image segmentation. [ABSTRACT FROM AUTHOR]

In this paper, we propose an attention-enhanced architecture for improved pneumonia detection in chest X-ray images. A unique attention mechanism is integrated with ResNet to highlight salient features crucial for pneumonia detection. Rigorous evaluation demonstrates that our attention mechanism significantly enhances pneumonia detection accuracy, achieving a satisfactory result of 96% accuracy. To address the issue of imbalanced training samples, we integrate an enhanced focal loss into our architecture. This approach assigns higher weights to minority classes during training, effectively mitigating data imbalance. Our model's performance significantly improves, surpassing that of traditional approaches such as the pretrained ResNet-50 model. Our attention-enhanced architecture thus presents a powerful solution for pneumonia detection in chest X-ray images, achieving an accuracy of 98%. By integrating enhanced focal loss, our approach effectively addresses imbalanced training sample. Comparative analysis underscores the positive impact of our model's spatial and channel attention modules. Overall, our study advances pneumonia detection in medical imaging and underscores the potential of attention-enhanced architectures for improved diagnostic accuracy and patient outcomes. Our findings offer valuable insights into image diagnosis and pneumonia prevention, contributing to future research in medical imaging and machine learning. [ABSTRACT FROM AUTHOR]

Background: Soft tissue sarcoma is a rare and highly heterogeneous tumor in clinical practice. Pathological grading of the soft tissue sarcoma is a key factor in patient prognosis and treatment planning while the clinical data of soft tissue sarcoma are imbalanced. In this paper, we propose an effective solution to find the optimal imbalance machine learning model for predicting the classification of soft tissue sarcoma data. Methods: In this paper, a large number of features are first obtained based on T 1 WI images using the radiomics methods.Then, we explore the methods of feature selection, sampling and classification, get 17 imbalance machine learning models based on the above features and performed extensive experiments to classify imbalanced soft tissue sarcoma data. Meanwhile, we used another dataset splitting method as well, which could improve the classification performance and verify the validity of the models. Results: The experimental results show that the combination of extremely randomized trees (ERT) classification algorithm using SMOTETomek and the recursive feature elimination technique (RFE) performs best compared to other methods. The accuracy of RFE+STT+ERT is 81.57% , which is close to the accuracy of biopsy, and the accuracy is 95.69% when using another dataset splitting method. Conclusion: Preoperative predicting pathological grade of soft tissue sarcoma in an accurate and noninvasive manner is essential. Our proposed machine learning method (RFE+STT+ERT) can make a positive contribution to solving the imbalanced data classification problem, which can favorably support the development of personalized treatment plans for soft tissue sarcoma patients. [ABSTRACT FROM AUTHOR]

Background: Corona Virus Disease 2019 (COVID-19) first appeared in December 2019, and spread rapidly around the world. COVID-19 is a pneumonia caused by novel coronavirus infection in 2019. COVID-19 is highly infectious and transmissible. By 7 May 2021, the total number of cumulative number of deaths is 3,259,033. In order to diagnose the infected person in time to prevent the spread of the virus, the diagnosis method for COVID-19 is extremely important. To solve the above problems, this paper introduces a Multi-Level Enhanced Sensation module (MLES), and proposes a new convolutional neural network model, MLES-Net, based on this module. Methods: Attention has the ability to automatically focus on the key points in various information, and Attention can realize parallelism, which can replace some recurrent neural networks to a certain extent and improve the efficiency of the model. We used the correlation between global and local features to generate the attention mask. First, the feature map was divided into multiple groups, and the initial attention mask was obtained by the dot product of each feature group and the feature after the global pooling. Then the attention masks were normalized. At the same time, there were two scaling and translating parameters in each group so that the normalize operation could be restored. Then, the final attention mask was obtained through the sigmoid function, and the feature of each location in the original feature group was scaled. Meanwhile, we use different classifiers on the network models with different network layers. Results: The network uses three classifiers, FC module (fully connected layer), GAP module (global average pooling layer) and GAPFC module (global average pooling layer and fully connected layer), to improve recognition efficiency. GAPFC as a classifier can obtain the best comprehensive effect by comparing the number of parameters, the amount of calculation and the detection accuracy. The experimental results show that the MLES-Net56-GAPFC achieves the best overall accuracy rate (95.27%) and the best recognition rate for COVID-19 category (100%). Conclusions: MLES-Net56-GAPFC has good classification ability for the characteristics of high similarity between categories of COVID-19 X-Ray images and low intra-category variability. Considering the factors such as accuracy rate, number of network model parameters and calculation amount, we believe that the MLES-Net56-GAPFC network model has better practicability. [ABSTRACT FROM AUTHOR]

Medical images such as CT and X-ray have been widely used for the detection of several chest infections and lung diseases. However, these images are susceptible to different types of noise, and it is hard to remove these noises due to their complex distribution. The presence of such noise significantly deteriorates the quality of the images and significantly affects the diagnosis performance. Hence, the design of an effective de-noising technique is highly essential to remove the noise from chest CT and X-ray images prior to further processing. Deep learning methods, mainly, CNN have shown tremendous progress on de-noising tasks. However, existing CNN based models estimate the noise from the final layers, which may not carry adequate details of the image. To tackle this issue, in this paper a deep multi-level semantic fusion network is proposed, called DMF-Net for the removal of noise from chest CT and X-ray images. The DMF-Net mainly comprises of a dilated convolutional feature extraction block, a cascaded feature learning block (CFLB) and a noise fusion block (NFB) followed by a prominent feature extraction block. The CFLB cascades the features from different levels (convolutional layers) which are later fed to NFB to attain correct noise prediction. Finally, the Prominent Feature Extraction Block(PFEB) produces the clean image. To validate the proposed de-noising technique, a separate and a mixed dataset containing high-resolution CT and X-ray images with specific and blind noise are used. Experimental results indicate the effectiveness of the DMF-Net compared to other state-of-the-art methods in the context of peak signal-to-noise ratio (PSNR) and structural similarity measurement (SSIM) while drastically cutting down on the processing power needed. [ABSTRACT FROM AUTHOR]

Background: Brain extraction is an essential prerequisite for the automated diagnosis of intracranial lesions and determines, to a certain extent, the accuracy of subsequent lesion recognition, location, and segmentation. Segmentation using a fully convolutional neural network (FCN) yields high accuracy but a relatively slow extraction speed. Methods: This paper proposes an integrated algorithm, FABEM, to address the above issues. This method first uses threshold segmentation, closed operation, convolutional neural network (CNN), and image filling to generate a specific mask. Then, it detects the number of connected regions of the mask. If the number of connected regions equals 1, the extraction is done by directly multiplying with the original image. Otherwise, the mask was further segmented using the region growth method for original images with single-region brain distribution. Conversely, for images with multi-region brain distribution, Deeplabv3 + is used to adjust the mask. Finally, the mask is multiplied with the original image to complete the extraction. Results: The algorithm and 5 FCN models were tested on 24 datasets containing different lesions, and the algorithm's performance showed MPA = 0.9968, MIoU = 0.9936, and MBF = 0.9963, comparable to the Deeplabv3+. Still, its extraction speed is much faster than the Deeplabv3+. It can complete the brain extraction of a head CT image in about 0.43 s, about 3.8 times that of the Deeplabv3+. Conclusion: Thus, this method can achieve accurate brain extraction from head CT images faster, creating a good basis for subsequent brain volume measurement and feature extraction of intracranial lesions. [ABSTRACT FROM AUTHOR]

Background: With the rapid spread of COVID-19 worldwide, quick screening for possible COVID-19 patients has become the focus of international researchers. Recently, many deep learning-based Computed Tomography (CT) image/X-ray image fast screening models for potential COVID-19 patients have been proposed. However, the existing models still have two main problems. First, most of the existing supervised models are based on pre-trained model parameters. The pre-training model needs to be constructed on a dataset with features similar to those in COVID-19 X-ray images, which limits the construction and use of the model. Second, the number of categories based on the X-ray dataset of COVID-19 and other pneumonia patients is usually imbalanced. In addition, the quality is difficult to distinguish, leading to non-ideal results with the existing model in the multi-class classification COVID-19 recognition task. Moreover, no researchers have proposed a COVID-19 X-ray image learning model based on unsupervised meta-learning. Methods: This paper first constructed an unsupervised meta-learning model for fast screening of COVID-19 patients (UMLF-COVID). This model does not require a pre-trained model, which solves the limitation problem of model construction, and the proposed unsupervised meta-learning framework solves the problem of sample imbalance and sample quality. Results: The UMLF-COVID model is tested on two real datasets, each of which builds a three-category and four-category model. And the experimental results show that the accuracy of the UMLF-COVID model is 3–10% higher than that of the existing models. Conclusion: In summary, we believe that the UMLF-COVID model is a good complement to COVID-19 X-ray fast screening models. [ABSTRACT FROM AUTHOR]