1. Influenza A/H1N1 septic shock in a patient with systemic lupus erythematosus. A case report
- Author
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Alexandros Sarantopoulos, Ritsa Tsioka, Panagiota Boura, Eleni Mouloudi, and Konstantinos Tselios
- Subjects
Oseltamivir ,Influenza A/H1N1 ,Anti-Inflammatory Agents ,Case Report ,medicine.disease_cause ,Antiviral Agents ,Virus ,lcsh:Infectious and parasitic diseases ,chemistry.chemical_compound ,Influenza A Virus, H1N1 Subtype ,systemic lupus erythematosus ,Influenza, Human ,Pandemic ,medicine ,Influenza A virus ,Humans ,Lupus Erythematosus, Systemic ,Vasoconstrictor Agents ,lcsh:RC109-216 ,skin and connective tissue diseases ,Lupus erythematosus ,Respiratory distress ,Septic shock ,business.industry ,Middle Aged ,medicine.disease ,Shock, Septic ,Anti-Bacterial Agents ,Infectious Diseases ,chemistry ,Shock (circulatory) ,Immunology ,septic shock ,Female ,Radiography, Thoracic ,Steroids ,medicine.symptom ,Tomography, X-Ray Computed ,business - Abstract
Background Immunocompromised patients, such as systemic lupus erythematosus (SLE) sufferers have an increased risk of mortality, following influenza infection. In the recent pandemic, influenza A H1NI virus caused 18449 deaths, mainly because of adult respiratory distress syndrome or bacterial co-infections. Case Presentation In this case report, an SLE patient with viral-induced septic shock, without overt pulmonary involvement, is discussed. The patient was administered oseltamivir and supportive treatment, including wide-spectrum antibiotics, vasopressors and steroids, according to the guidelines proposed for bacterial sepsis and septic shock. She finally survived and experienced a lupus flare soon after intensive care unit (ICU) discharge. Conclusions To our knowledge, this is the first case to report severe septic shock from influenza A/H1N1 virus, without overt pulmonary involvement.
- Published
- 2011
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