1. Evaluation of methicillin-resistant Staphylococcus aureus (MRSA) bacteremia: Epidemiology, clinical characteristics, and outcomes in the older patients in a tertiary teaching hospital in Malaysia
- Author
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Kejal Hasmukharay, Soo Tein Ngoi, Nor Izzati Saedon, Kit Mun Tan, Hui Min Khor, Ai Vyrn Chin, Maw Pin Tan, Adeeba Kamarulzaman, Nuryana binti Idris, Wen Kiong Niek, Cindy Shuan Ju Teh, Shahrul Bahyah binti Kamaruzzaman, and Sasheela Sri La Sri Ponnampalavanar
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Healthcare-associated ,Hospital-acquired ,Hypoalbuminemia ,Methicillin-resistant Staphylococcus aureus (MRSA) ,Older adults ,Risk factors ,Infectious and parasitic diseases ,RC109-216 - Abstract
Abstract Background Methicillin-resistant Staphylococcus aureus (MRSA) bacteremia is a major concern in the global healthcare system. However, data from Asian regions dealing with the singularity of this infection in older persons is lacking. We aimed to identify the differences in the clinical characteristics and outcomes of MRSA bacteremia between adults aged 18–64 and ≥ 65 years. Methods A retrospective study cohort was conducted at the University Malaya Medical Centre (UMMC) on cases of MRSA bacteremia from 2012 to 2016. Patient demographic and clinical data were collected for risk factors analyses. Results New cases of MRSA bacteremia showed a trend of increase from 0.12 to 100 admissions in 2012 to 0.17 per 100 admissions in 2016 but a drop was observed in 2014 (0.07 per 100 admissions). Out of the 275 patients with MRSA bacteremia, 139 (50.5%) patients were aged ≥ 65 years old. Co-morbidities and severity at presentation were significantly higher among older adults, including diabetes mellitus (p = 0.035), hypertension (p = 0.001), and ischemic heart disease (p
- Published
- 2023
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